Compounds > clodronic acid
Page last updated: 2024-08-22

clodronic acid and Insulin Resistance

clodronic acid has been researched along with Insulin Resistance in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's9 (81.82)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Hasuzawa, N; Kabashima, M; Nomura, M; Tatsushima, K; Tokubuchi, R1
Bader, JE; Carson, MS; Enos, RT; McGuinness, OP; Murphy, EA; Robinson, CM; Sougiannis, AT; Velázquez, KT1
Cheon, HG; Choi, HE; Jeon, EJ; Kim, DY; Lee, NH1
Cani, PD; Horsmans, Y; Lanthier, N; Lebrun, V; Leclercq, IA; Molendi-Coste, O; Sempoux, C; Stärkel, P; van Rooijen, N1
Bu, L; Gao, M; Liu, D; Qu, S1
Goto, T; Kawada, T; Kuwata, H; Maruno, K; Nitta, T; Sakamoto, T; Takahashi, N; Tomita, K; Yeh, YS1
Chen, X; Leong, J; Liu, W; Luo, P; Sears, ML; Woodland, DC1
Clementi, AH; Gaudy, AM; Mooney, RA; Pierce, RH; van Rooijen, N1
Cani, PD; Horsmans, Y; Lanthier, N; Leclercq, IA; Molendi-Coste, O; van Rooijen, N2
Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Tsai, TH; Yang, YY1

Reviews

1 review(s) available for clodronic acid and Insulin Resistance

ArticleYear
[VNUT Is a Therapeutic Target for Type 2 Diabetes and NASH].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2021, Volume: 141, Issue:4

    Topics: Adenosine Triphosphate; Animals; Clodronic Acid; Diabetes Mellitus, Type 2; Drug Discovery; Humans; Insulin Resistance; Insulin Secretion; Mice, Knockout; Molecular Targeted Therapy; Non-alcoholic Fatty Liver Disease; Nucleotide Transport Proteins; Secretory Vesicles

2021

Other Studies

10 other study(ies) available for clodronic acid and Insulin Resistance

ArticleYear
Repeated clodronate-liposome treatment results in neutrophilia and is not effective in limiting obesity-linked metabolic impairments.
    American journal of physiology. Endocrinology and metabolism, 2019, 03-01, Volume: 316, Issue:3

    Topics: Adipose Tissue; Animals; Body Weight; Clodronic Acid; Cytokines; Diet, Fat-Restricted; Diet, High-Fat; Energy Intake; Insulin Resistance; Lipid Metabolism; Liposomes; Liver; Macrophages; Male; Mice; Neutrophils; Non-alcoholic Fatty Liver Disease; Obesity; RNA, Messenger

2019
Telmisartan induces browning of fully differentiated white adipocytes via M2 macrophage polarization.
    Scientific reports, 2019, 02-04, Volume: 9, Issue:1

    Topics: Adipocytes, Brown; Adipocytes, White; Adipose Tissue, White; Angiotensin II Type 1 Receptor Blockers; Animals; Catecholamines; Cell Differentiation; Clodronic Acid; Culture Media, Conditioned; Humans; Insulin Resistance; Macrophage Activation; Macrophages; Male; Mice; Obesity; PPAR gamma; RAW 264.7 Cells; Receptors, Cytoplasmic and Nuclear; Telmisartan

2019
Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice.
    Clinical science (London, England : 1979), 2013, Volume: 125, Issue:11

    Topics: Alcohol Drinking; Animals; Blood Glucose; Clodronic Acid; Fatty Liver; Female; Glucose; Homeostasis; Hydroxides; Insulin Resistance; Kupffer Cells; Macrophage Activation; Mice; Mice, Inbred C57BL; Oxidative Stress; Peroxisome Proliferators; PPAR alpha; Pyrimidines

2013
Intraperitoneal injection of clodronate liposomes eliminates visceral adipose macrophages and blocks high-fat diet-induced weight gain and development of insulin resistance.
    The AAPS journal, 2013, Volume: 15, Issue:4

    Topics: Animals; Clodronic Acid; Diet, High-Fat; Injections, Intraperitoneal; Insulin Resistance; Intra-Abdominal Fat; Liposomes; Macrophages; Mice; Mice, Inbred C57BL; Weight Gain

2013
Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice.
    American journal of physiology. Endocrinology and metabolism, 2016, 04-15, Volume: 310, Issue:8

    Topics: Adipocytes, Beige; Adipocytes, Brown; Adipose Tissue; Animals; Cell Differentiation; Clodronic Acid; Cold Temperature; Diet, High-Fat; Energy Metabolism; Immunoblotting; Immunohistochemistry; Insulin Resistance; Liposomes; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thermogenesis; Tumor Necrosis Factor-alpha; Uncoupling Protein 1

2016
Short-term high-fat feeding induces islet macrophage infiltration and β-cell replication independently of insulin resistance in mice.
    American journal of physiology. Endocrinology and metabolism, 2016, 10-01, Volume: 311, Issue:4

    Topics: Adipose Tissue; Animals; Blood Glucose; Cell Division; Clodronic Acid; Diet, High-Fat; Epididymis; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Macrophages; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Oxidative Stress

2016
Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling.
    Biochimica et biophysica acta, 2009, Volume: 1792, Issue:11

    Topics: Adipose Tissue; Animals; Bone Density Conservation Agents; Clodronic Acid; Diet; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Inflammation Mediators; Insulin; Insulin Resistance; Interleukin-10; Interleukin-6; Kupffer Cells; Liposomes; Macrophages; Male; Mice; Obesity; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Insulin; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Triglycerides

2009
Kupffer cell activation is a causal factor for hepatic insulin resistance.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:1

    Topics: Adipose Tissue; Animals; Clodronic Acid; Dietary Fats; Drug Delivery Systems; Fatty Liver; Glucose Clamp Technique; Hepatitis; Hyperinsulinism; Injections, Intravenous; Insulin; Insulin Resistance; Kupffer Cells; Liposomes; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; Signal Transduction

2010
Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:12

    Topics: Adipose Tissue; Adiposity; Animals; Clodronic Acid; Diet, High-Fat; Fatty Liver; Inflammation; Insulin Resistance; Kupffer Cells; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity

2011
Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis.
    Clinical science (London, England : 1979), 2012, Volume: 123, Issue:12

    Topics: Analysis of Variance; Animals; Arachidonic Acid; Benzofurans; Choline; Clodronic Acid; Diet, High-Fat; DNA Primers; Fatty Acids, Unsaturated; Fatty Liver; Gadolinium; Hemodynamics; Hypertension, Portal; Insulin Resistance; Kupffer Cells; Leptin; Methionine; Methoxamine; Microcirculation; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Receptors, Thromboxane A2, Prostaglandin H2; RNA, Messenger; Sulfonylurea Compounds; Thiobarbituric Acid Reactive Substances; Thromboxane A2

2012