Page last updated: 2024-08-22

clodronic acid and Bone Loss, Perimenopausal

clodronic acid has been researched along with Bone Loss, Perimenopausal in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (27.27)18.2507
2000's17 (51.52)29.6817
2010's7 (21.21)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adami, S; Dartizio, C; Fracassi, E; Gatti, D; Idolazzi, L; Ionescu, C; Kunnathully, V; Rossini, M; Troplini, S; Viapiana, O1
Baraldi, E; Cremonesi, G; Frediani, B1
Jalava, T; Johansson, H; Kanis, JA; Kayan, K; McCloskey, EV; Oden, A; Pande, K; Vasireddy, S1
Johansson, H; Kanis, JA; Kayan, K; McCloskey, EV; Oden, A; Orgee, J; Pande, K; Vasireddy, S1
Kessenich, C1
Calcagnile, F; Muratore, M; Quarta, E; Quarta, L1
Alhava, E; Härmä, K; Honkanen, R; Jurvelin, J; Kiviniemi, V; Komulainen, M; Kröger, H; Saarikoski, S; Tuppurainen, M1
Frediani, B1
Calcagnile, F; Grimaldi, A; Muratore, M; Quarta, E; Quarta, L1
Baraldi, E; Cremonesi, G; Leuratti, C; Mariotti, F; Radicioni, M1
Ala-Kaila, K; Aranko, SM; Blåfield, H; Koivunoro, K; Kormano, M; Laitinen, K; Mäkinen, L; Patronen, A; Perttilä, J; Puolijoki, H; Pylkkänen, L; Rekiaro, M; Sairanen, S; Salmi, J; Seppänen, J; Väisänen, K; Välimäki, MJ; Vesterinen, K1
Fietta, P; Lodigiani, L; Manganelli, P1
Calcagnile, F; Carlo Isaia, G; Cosentino, L; D'Amelio, P; Muratore, M; Quarta, E; Tamone, C; Tinelli, F1
Adami, S; Crepaldi, G; Filipponi, P; Sartori, L1
Adams, J; Aropuu, S; Beneton, M; Davies, M; Francis, RM; Jalava, T; Kanis, JA; Kayan, K; Kenraali, J; McCloskey, E; Pylkkänen, L; Robinson, J; Selby, P1
Alessi, MA; Barbagallo, M; Belvedere, M; Bevilacqua, M; Costanza, G; Dominguez, LJ; Ferlisi, A; Galioto, A; Putignano, E1
Langdahl, B; Mosekilde, L; Vestergaard, P1
Alagöl, F; Bayraktaroglu, T; Boztepe, H; Tanakol, R; Yarman, S1
Alva, D; Cesareo, R; Contini, S; De Rosa, B; Iozzino, M; Lauria, A; Mallardo, L; Napolitano, C; Orsini, A; Reda, G1
Boldrini, S; Cini, L; Cristallini, S; Fedeli, L; Filipponi, P; Massoni, C; Palumbo, R; Pedetti, M1
Hanhijärvi, H; Hyvönen, PM; Karhi, T; Kosma, VM; Liimola-Luoma, L1
Crepaldi, G; D'Angelo, A; Dalle Carbonare, L; Giannini, S; Passeri, G; Sartori, L1
Beneton, MN; Kanis, JA; McCloskey, EV1
Licata, AA1
Arnala, I; Heikkinen, JE; Laitinen, K; Selander, KS; Väänänen, HK1
Gennari, C; Reginster, JY1
Adami, S; Braga, V; Gatti, D; Gerardi, D; Rossini, M; Zamberlan, N1
Cheng, WC; Chieng, PU; Hsu, SH; Tsai, KS; Yang, RS1
del Puente, A; Ferrara, G; Itto, E; Oriente, P; Scognamiglio, A1
Borean, A; De Prà, M; Farina, G; Nalin, P; Rizzotti, P1
Watts, NB1
Fini, M; Gnudi, S; Lisi, L; Malavolta, N1
Biberoğlu, K; Noyan, V; Tiraş, MB; Yildiz, A1

Reviews

9 review(s) available for clodronic acid and Bone Loss, Perimenopausal

ArticleYear
Effect of clodronate treatment on risk of fracture: a systematic review and meta-analysis.
    Calcified tissue international, 2014, Volume: 95, Issue:4

    Topics: Bone Density Conservation Agents; Clodronic Acid; Female; Fracture Healing; Fractures, Bone; Humans; Male; Osteoporosis; Osteoporosis, Postmenopausal; Probability; Prospective Studies; Randomized Controlled Trials as Topic

2014
Clinical utility of clodronate in the prevention and management of osteoporosis in patients intolerant of oral bisphosphonates.
    Drug design, development and therapy, 2011, Volume: 5

    Topics: Clodronic Acid; Diphosphonates; Female; Humans; Male; Osteoporosis; Osteoporosis, Postmenopausal

2011
Injectable bisphosphonates in the treatment of postmenopausal osteoporosis.
    Aging clinical and experimental research, 2003, Volume: 15, Issue:4

    Topics: Anti-Inflammatory Agents; Clodronic Acid; Diphosphonates; Female; Humans; Ibandronic Acid; Imidazoles; Infusions, Intravenous; Middle Aged; Osteoporosis, Postmenopausal; Pamidronate; Zoledronic Acid

2003
Fracture prevention in postmenopausal women.
    Clinical evidence, 2006, Issue:15

    Topics: Aged; Alendronate; Bone Density Conservation Agents; Calcitonin; Calcium; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Spontaneous; Hormone Replacement Therapy; Humans; Ibandronic Acid; Osteoporosis, Postmenopausal; Pamidronate; Parathyroid Hormone; Risedronic Acid; Selective Estrogen Receptor Modulators; Vitamin D

2006
Evidence based medicine and effective interventions of pharmacological therapy for the prevention of osteoporotic fractures.
    Minerva endocrinologica, 2007, Volume: 32, Issue:4

    Topics: Alendronate; Bone Density Conservation Agents; Bone Resorption; Calcitonin; Clodronic Acid; Diphosphonates; Etidronic Acid; Evidence-Based Medicine; Female; Fractures, Bone; Humans; Ibandronic Acid; Organometallic Compounds; Osteoporosis, Postmenopausal; Risedronic Acid; Selective Estrogen Receptor Modulators; Teriparatide; Thiophenes; Vitamin D

2007
Clodronate and osteoporosis.
    Maturitas, 1996, Volume: 23 Suppl

    Topics: Administration, Oral; Aged; Bone Density; Clodronic Acid; Female; Humans; Infusions, Intravenous; Long-Term Care; Osteoporosis, Postmenopausal; Treatment Outcome

1996
Bisphosphonate therapy.
    The American journal of the medical sciences, 1997, Volume: 313, Issue:1

    Topics: Alendronate; Animals; Bone Density; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Osteoclasts; Osteoporosis; Osteoporosis, Postmenopausal; Pamidronate; Risedronic Acid

1997
Bisphosphonates and osteoporosis treatment in Italy.
    Aging (Milan, Italy), 1998, Volume: 10, Issue:4

    Topics: Aged; Alendronate; Bone and Bones; Bone Density; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Italy; Middle Aged; Osteoporosis; Osteoporosis, Postmenopausal; Safety

1998
Treatment of osteoporosis with bisphosphonates.
    Rheumatic diseases clinics of North America, 2001, Volume: 27, Issue:1

    Topics: Aged; Alendronate; Bone and Bones; Bone Density; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Middle Aged; Osteoporosis, Postmenopausal; Pamidronate; Risedronic Acid

2001

Trials

19 trial(s) available for clodronic acid and Bone Loss, Perimenopausal

ArticleYear
Distinct effect of zoledronate and clodronate on circulating levels of DKK1 and sclerostin in women with postmenopausal osteoporosis.
    Bone, 2014, Volume: 67

    Topics: Adaptor Proteins, Signal Transducing; Aged; Bone Density Conservation Agents; Bone Morphogenetic Proteins; Clodronic Acid; Diphosphonates; Female; Genetic Markers; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Middle Aged; Osteoporosis, Postmenopausal; Zoledronic Acid

2014
Ten-year fracture probability identifies women who will benefit from clodronate therapy--additional results from a double-blind, placebo-controlled randomised study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:5

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Algorithms; Bone Density; Bone Density Conservation Agents; Clodronic Acid; Double-Blind Method; Female; Fractures, Bone; Hip Joint; Humans; Osteoporosis, Postmenopausal; Probability; Risk Assessment; Risk Factors; Treatment Outcome; United Kingdom

2009
Can fall risk be incorporated into fracture risk assessment algorithms: a pilot study of responsiveness to clodronate.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:12

    Topics: Accidental Falls; Aged; Aged, 80 and over; Algorithms; Bone Density; Bone Density Conservation Agents; Clodronic Acid; Epidemiologic Methods; Female; Femur Neck; Humans; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Prognosis; Treatment Outcome

2009
"Twice-a-month" clodronate 200 mg IM: a new dosing regimen and improved therapy adherence in the treatment of postmenopausal osteoporosis.
    Advances in therapy, 2010, Volume: 27, Issue:5

    Topics: Aged; Bone Density; Bone Density Conservation Agents; Bone Resorption; Clodronic Acid; Drug Administration Schedule; Female; Femur; Humans; Lumbar Vertebrae; Medication Adherence; Middle Aged; Osteoporosis, Postmenopausal; Pain

2010
Effects of continuous combined hormone replacement therapy and clodronate on bone mineral density in osteoporotic postmenopausal women: a 5-year follow-up.
    Maturitas, 2010, Volume: 66, Issue:4

    Topics: Alkaline Phosphatase; Bone Density; Bone Density Conservation Agents; Clodronic Acid; Drug Therapy, Combination; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Femur; Finland; Follow-Up Studies; Humans; Lumbar Vertebrae; Middle Aged; Norethindrone; Norethindrone Acetate; Osteoporosis, Postmenopausal; Postmenopause; Prospective Studies

2010
Effects of two administration schemes of intramuscular clodronic acid on bone mineral density: a randomized, open-label, parallel-group study.
    Clinical drug investigation, 2011, Volume: 31, Issue:1

    Topics: Aged; Aged, 80 and over; Bone Density; Bone Density Conservation Agents; Clodronic Acid; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Middle Aged; Osteoporosis, Postmenopausal

2011
Pharmacokinetic and tolerability of i.m. disodium clodronate 200 mg/lidocaine 1%, given twice monthly, in comparison with i.m. disodium clodronate 100 mg/lidocaine 1%, given weekly, in healthy postmenopausal female patients.
    International journal of clinical pharmacology and therapeutics, 2013, Volume: 51, Issue:4

    Topics: Bone Density Conservation Agents; Clodronic Acid; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Injections, Intramuscular; Lidocaine; Middle Aged; Osteoporosis, Postmenopausal; Postmenopause; Therapeutic Equivalency

2013
Prevention of bone loss by clodronate in early postmenopausal women with vertebral osteopenia: a dose-finding study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2002, Volume: 13, Issue:12

    Topics: Absorptiometry, Photon; Bone Density; Bone Diseases, Metabolic; Clodronic Acid; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Hip Joint; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Spinal Diseases

2002
Effect of raloxifene and clodronate on bone density in postmenopausal osteoporotic women.
    International journal of tissue reactions, 2003, Volume: 25, Issue:2

    Topics: Absorptiometry, Photon; Aged; Biomarkers; Bone Density; Bone Remodeling; Bone Resorption; Cholecalciferol; Clodronic Acid; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2003
Clodronate reduces vertebral fracture risk in women with postmenopausal or secondary osteoporosis: results of a double-blind, placebo-controlled 3-year study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2004, Volume: 19, Issue:5

    Topics: Aged; Alkaline Phosphatase; Antimetabolites; Bone Density; Clodronic Acid; Collagen; Collagen Type I; Double-Blind Method; Female; Humans; Middle Aged; Osteoporosis; Osteoporosis, Postmenopausal; Peptides; Prospective Studies; Risk Factors; Spinal Fractures

2004
Intermittent intramuscular clodronate therapy: a valuable option for older osteoporotic women.
    Age and ageing, 2005, Volume: 34, Issue:6

    Topics: Aged; Back Pain; Bone Density; Bone Density Conservation Agents; Calcium; Clodronic Acid; Drug Administration Schedule; Drug Therapy, Combination; Female; Femur; Humans; Injections, Intramuscular; Lumbar Vertebrae; Osteoporosis, Postmenopausal; Pain Measurement; Treatment Outcome; Vitamin D

2005
Clodronic acid in the treatment of postmenopausal osteoporosis.
    Clinical drug investigation, 2007, Volume: 27, Issue:6

    Topics: Aged; Bone Density; Bone Density Conservation Agents; Calcium; Clodronic Acid; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Prospective Studies; Vitamin D; Vitamins

2007
Cyclical clodronate is effective in preventing postmenopausal bone loss: a comparative study with transcutaneous hormone replacement therapy.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:5

    Topics: Absorptiometry, Photon; Administration, Cutaneous; Adult; Analysis of Variance; Biomarkers; Bone Density; Bone Development; Clodronic Acid; Estradiol; Estrogen Replacement Therapy; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Lumbar Vertebrae; Medroxyprogesterone; Middle Aged; Osteoporosis, Postmenopausal; Skin Absorption

1995
Continuous and cyclical clodronate therapies and bone density in postmenopausal bone loss.
    Obstetrics and gynecology, 1996, Volume: 88, Issue:3

    Topics: Absorptiometry, Photon; Aged; Bone Density; Bone Remodeling; Calcium; Clodronic Acid; Drug Administration Schedule; Female; Femur; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Time Factors

1996
Short-term intravenous bisphosphonates in prevention of postmenopausal bone loss.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:1

    Topics: Absorptiometry, Photon; Bone Density; Calcitriol; Calcium; Clodronic Acid; Collagen; Collagen Type I; Creatinine; Dose-Response Relationship, Drug; Double-Blind Method; Etidronic Acid; Female; Femur Neck; Follow-Up Studies; Humans; Hydroxyproline; Injections, Intravenous; Longitudinal Studies; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Peptide Fragments; Peptides; Procollagen; Prospective Studies

1997
Intramuscular clodronate therapy in postmenopausal osteoporosis.
    Bone, 1999, Volume: 24, Issue:2

    Topics: Aged; Bone Density; Clodronic Acid; Female; Humans; Injections, Intramuscular; Middle Aged; Osteoporosis, Postmenopausal; Pain; Patient Compliance; Time Factors

1999
The effectiveness of cyclic and continuous oral clodronate therapy on bone density and markers in osteopenic postmenopausal women.
    Calcified tissue international, 1999, Volume: 64, Issue:5

    Topics: Absorptiometry, Photon; Administration, Oral; Aged; Biomarkers; Bone and Bones; Bone Density; Bone Resorption; Clodronic Acid; Collagen; Collagen Type I; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Femur Neck; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Peptide Fragments; Peptides; Procollagen; Treatment Outcome

1999
Intramuscular clodronate in nonresponders to oral alendronate therapy for osteoporosis.
    The Journal of rheumatology, 2000, Volume: 27, Issue:8

    Topics: Absorptiometry, Photon; Administration, Oral; Aged; Alendronate; Alkaline Phosphatase; Analgesics, Non-Narcotic; Bone Density; Case-Control Studies; Clodronic Acid; Female; Femur Neck; Humans; Injections, Intramuscular; Middle Aged; Osteoporosis, Postmenopausal; Treatment Outcome

2000
Comparison of different treatment modalities for postmenopausal patients with osteopenia: hormone replacement therapy, calcitonin and clodronate.
    Climacteric : the journal of the International Menopause Society, 2000, Volume: 3, Issue:2

    Topics: Adult; Alkaline Phosphatase; Bone Density; Calcitonin; Calcium; Clodronic Acid; Drug Therapy, Combination; Estrogen Replacement Therapy; Female; Femur; Humans; Lumbar Vertebrae; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal; Phosphorus; Treatment Outcome

2000

Other Studies

5 other study(ies) available for clodronic acid and Bone Loss, Perimenopausal

ArticleYear
Postmenopausal osteoporosis. The role of intravenous bisphosphonates.
    Advance for nurse practitioners, 2008, Volume: 16, Issue:11

    Topics: Bone Density Conservation Agents; Clodronic Acid; Female; Fractures, Bone; Humans; Male; Middle Aged; Osteoporosis, Postmenopausal; Patient Compliance; United States

2008
Clodronate induced uveitis.
    Annals of the rheumatic diseases, 2003, Volume: 62, Issue:4

    Topics: Aged; Antimetabolites; Clodronic Acid; Female; Humans; Osteoporosis, Postmenopausal; Uveitis, Anterior

2003
The influence of dichloromethylene bisphosphonate on the healing of a long bone fracture, composition of bone mineral and histology of bone in the rat.
    Pharmacology & toxicology, 1994, Volume: 75, Issue:6

    Topics: Animals; Body Weight; Bone Density; Calcium; Clodronic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Female; Femoral Fractures; Femur; Fluorides; Fracture Healing; Humans; Injections, Subcutaneous; Magnesium; Osteocalcin; Osteoporosis, Postmenopausal; Phosphorus; Rats; Rats, Sprague-Dawley

1994
Levels of C-telopeptide fragments of collagen type I enable the monitoring and early adjustment of clodronate therapy in patients with postmenopausal osteoporosis.
    Clinical chemistry and laboratory medicine, 2000, Volume: 38, Issue:6

    Topics: Aged; Analgesics, Non-Narcotic; Clodronic Acid; Collagen; Drug Monitoring; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Peptide Fragments

2000
Effect of intramuscular clodronate on bone mass and metabolism in osteoporotic women.
    International journal of tissue reactions, 2001, Volume: 23, Issue:1

    Topics: Aged; Analgesics, Non-Narcotic; Bone Density; Calcium; Clodronic Acid; Female; Femur Neck; Follow-Up Studies; Humans; Hydroxyproline; Injections, Intramuscular; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Parathyroid Hormone; Phosphates

2001