clobenpropit has been researched along with Skin Neoplasms in 1 studies
clobenpropit: histamine H3 receptor antagonist
clobenpropit : An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
Skin Neoplasms: Tumors or cancer of the SKIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have previously reported that histamine at micromolar concentrations reduces the proliferation of melanoma cell lines." | 7.77 | Role of H4 receptor in histamine-mediated responses in human melanoma. ( Bergoc, RM; Cricco, GP; Croci, M; Martinel Lamas, DJ; Massari, NA; Medina, VA; Rivera, ES; Sambuco, L, 2011) |
| "We have previously reported that histamine at micromolar concentrations reduces the proliferation of melanoma cell lines." | 3.77 | Role of H4 receptor in histamine-mediated responses in human melanoma. ( Bergoc, RM; Cricco, GP; Croci, M; Martinel Lamas, DJ; Massari, NA; Medina, VA; Rivera, ES; Sambuco, L, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Massari, NA | 1 |
| Medina, VA | 1 |
| Martinel Lamas, DJ | 1 |
| Cricco, GP | 1 |
| Croci, M | 1 |
| Sambuco, L | 1 |
| Bergoc, RM | 1 |
| Rivera, ES | 1 |
1 other study available for clobenpropit and Skin Neoplasms
| Article | Year |
|---|---|
Role of H4 receptor in histamine-mediated responses in human melanoma.
Topics: Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Guanidines; Histamine; Humans; Imidaz | 2011 |