clobenpropit has been researched along with Rhinitis, Allergic, Perennial in 1 studies
clobenpropit: histamine H3 receptor antagonist
clobenpropit : An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
Rhinitis, Allergic, Perennial: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yokota, E | 1 |
| Kuyama, S | 1 |
| Ogawa, M | 1 |
| Kamei, C | 1 |
1 other study available for clobenpropit and Rhinitis, Allergic, Perennial
| Article | Year |
|---|---|
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Hista | 2008 |