clobenpropit has been researched along with Mesenteric Vascular Occlusion in 1 studies
clobenpropit: histamine H3 receptor antagonist
clobenpropit : An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
Mesenteric Vascular Occlusion: Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with clobenpropit was without any effect on control MBF and AP but significantly reduced most of RH responses." | 1.32 | Histamine H3 receptors modulate reactive hyperemia in rat gut. ( Biernat, J; Brzozowski, T; Konturek, SJ; Obuchowicz, R; Pawlik, MW; Pawlik, WW; Sendur, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pawlik, WW | 1 |
| Obuchowicz, R | 1 |
| Pawlik, MW | 1 |
| Sendur, R | 1 |
| Biernat, J | 1 |
| Brzozowski, T | 1 |
| Konturek, SJ | 1 |
1 other study available for clobenpropit and Mesenteric Vascular Occlusion
| Article | Year |
|---|---|
Histamine H3 receptors modulate reactive hyperemia in rat gut.
Topics: Animals; Blood Pressure; Female; Histamine Agonists; Histamine Antagonists; Hyperemia; Imidazoles; I | 2004 |