clobenpropit has been researched along with Hemorrhagic Shock in 1 studies
clobenpropit: histamine H3 receptor antagonist
clobenpropit : An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The main causes of hemorrhagic shock involve: (1) forces causing injury; and (2) diseases that can cause hemorrhage." | 1.48 | Cardiovascular effects of H3 histamine receptor inverse agonist/ H4 histamine receptor agonist, clobenpropit, in hemorrhage-shocked rats. ( Biskupek-Wanot, A; Jasikowska, K; Niewiadomska, E; Wanot, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wanot, B | 1 |
| Jasikowska, K | 1 |
| Niewiadomska, E | 1 |
| Biskupek-Wanot, A | 1 |
1 other study available for clobenpropit and Hemorrhagic Shock
| Article | Year |
|---|---|
Cardiovascular effects of H3 histamine receptor inverse agonist/ H4 histamine receptor agonist, clobenpropit, in hemorrhage-shocked rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Histamine Agonists; Imidazoles; Male; Rat | 2018 |