clobenpropit has been researched along with Encephalopathy, Toxic in 1 studies
clobenpropit: histamine H3 receptor antagonist
clobenpropit : An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Badenhorst, HE | 1 |
Maharaj, DS | 1 |
Malan, SF | 1 |
Daya, S | 1 |
van Dyk, S | 1 |
1 other study available for clobenpropit and Encephalopathy, Toxic
Article | Year |
---|---|
Histamine-3 receptor antagonists reduce superoxide anion generation and lipid peroxidation in rat brain homogenates.
Topics: Animals; Antioxidants; Aspirin; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; His | 2005 |