clobenpropit has been researched along with Colorectal Neoplasms in 1 studies
clobenpropit: histamine H3 receptor antagonist
clobenpropit : An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, Z | 1 |
| Yao, W | 1 |
| Xiong, Y | 1 |
| Li, J | 1 |
| Liu, L | 1 |
| Shi, L | 1 |
| Zhang, W | 1 |
| Zhang, C | 1 |
| Nie, L | 1 |
| Wan, J | 1 |
1 other study available for clobenpropit and Colorectal Neoplasms
| Article | Year |
|---|---|
Attenuated expression of HRH4 in colorectal carcinomas: a potential influence on tumor growth and progression.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell | 2011 |