clobenpropit has been researched along with Body Weight in 2 studies
clobenpropit: histamine H3 receptor antagonist
clobenpropit : An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leptin is a key signal linking peripheral adiposity levels to the regulation of energy homeostasis in the brain." | 5.35 | Comparison of the effect of an H(3)-inverse agonist on energy intake and hypothalamic histamine release in normal mice and leptin resistant mice with high fat diet-induced obesity. ( Hatano, K; Ishizuka, T; Murotani, T; Yamatodani, A, 2008) |
| "Leptin is a key signal linking peripheral adiposity levels to the regulation of energy homeostasis in the brain." | 1.35 | Comparison of the effect of an H(3)-inverse agonist on energy intake and hypothalamic histamine release in normal mice and leptin resistant mice with high fat diet-induced obesity. ( Hatano, K; Ishizuka, T; Murotani, T; Yamatodani, A, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Szczepańska, K | 1 |
| Pockes, S | 1 |
| Podlewska, S | 1 |
| Höring, C | 1 |
| Mika, K | 1 |
| Latacz, G | 1 |
| Bednarski, M | 1 |
| Siwek, A | 1 |
| Karcz, T | 1 |
| Nagl, M | 1 |
| Bresinsky, M | 1 |
| Mönnich, D | 1 |
| Seibel, U | 1 |
| Kuder, KJ | 1 |
| Kotańska, M | 1 |
| Stark, H | 1 |
| Elz, S | 1 |
| Kieć-Kononowicz, K | 1 |
| Ishizuka, T | 1 |
| Hatano, K | 1 |
| Murotani, T | 1 |
| Yamatodani, A | 1 |
2 other studies available for clobenpropit and Body Weight
| Article | Year |
|---|---|
Structural modifications in the distal, regulatory region of histamine H
Topics: Animals; Anti-Obesity Agents; Body Weight; Dose-Response Relationship, Drug; Female; Histamine H3 An | 2021 |
Comparison of the effect of an H(3)-inverse agonist on energy intake and hypothalamic histamine release in normal mice and leptin resistant mice with high fat diet-induced obesity.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chromatography, High Pressure Liquid; | 2008 |