Page last updated: 2024-10-25

clobenpropit and Aura

clobenpropit has been researched along with Aura in 1 studies

clobenpropit: histamine H3 receptor antagonist
clobenpropit : An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.

Research Excerpts

ExcerptRelevanceReference
"To investigate the mechanisms of histamine on chronic epilepsy induced by pentylenetetrazole (PTZ)."7.72[Mechanisms of the effect of brain histamine on chronic epilepsy induced by pentylenetetrazole]. ( Chen, Z; Hu, WW; Jin, CL; Shen, HQ; Zhang, LS; Zhao, MH, 2004)
"To investigate the mechanisms of histamine on chronic epilepsy induced by pentylenetetrazole (PTZ)."3.72[Mechanisms of the effect of brain histamine on chronic epilepsy induced by pentylenetetrazole]. ( Chen, Z; Hu, WW; Jin, CL; Shen, HQ; Zhang, LS; Zhao, MH, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, LS1
Shen, HQ1
Jin, CL1
Hu, WW1
Zhao, MH1
Chen, Z1

Other Studies

1 other study available for clobenpropit and Aura

ArticleYear
[Mechanisms of the effect of brain histamine on chronic epilepsy induced by pentylenetetrazole].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2004, Volume: 33, Issue:3

    Topics: Animals; Brain; Chronic Disease; Dose-Response Relationship, Drug; Epilepsy; Histamine; Histidine; I

2004