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clobazam and Seizures, Febrile

clobazam has been researched along with Seizures, Febrile in 6 studies

Clobazam: A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
clobazam : 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substituted by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics.

Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

Research Excerpts

ExcerptRelevanceReference
"Febrile seizures are the most common type of seizure among children that can be prevented by using prophylactic drugs like Clobazam and Diazepam."1.40Intermittent prophylaxis of recurrent febrile seizures with clobazam versus diazepam. ( Ahmed, AU; Banu, LA; Begum, SA; Haque, MA; Hoque, MR; Karim, MM; Momen, A; Parveen, F; Quddush, MR; Saha, SK; Sattar, S, 2014)
"Clobazam was administered orally during the febrile episode according to the child's weight: up to 5 kg, 5 mg/day; from 5 to 10 kg, 10 mg/day; from 11 to 15 kg, 15 mg/day, and over 15 kg, 20 mg/day."1.30Treatment of febrile seizures with intermittent clobazam. ( Diament, A; Gherpelli, JL; Heise, CO; Machado-Haertel, LR; Manreza, ML; Pedreira, CC, 1997)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sattar, S1
Saha, SK1
Parveen, F1
Banu, LA1
Momen, A1
Ahmed, AU1
Quddush, MR1
Karim, MM1
Begum, SA1
Haque, MA1
Hoque, MR1
Khosroshahi, N1
Faramarzi, F1
Salamati, P1
Haghighi, SM1
Kamrani, K1
Rose, W1
Kirubakaran, C1
Scott, JX1
Guran, P1
Blanc, A1
Manreza, ML1
Gherpelli, JL1
Machado-Haertel, LR1
Pedreira, CC1
Heise, CO1
Diament, A1
Tondi, M1
Carboni, F1
Deriu, A1
Manca, S1
Mastropaolo, C1

Trials

2 trials available for clobazam and Seizures, Febrile

ArticleYear
Diazepam versus clobazam for intermittent prophylaxis of febrile seizures.
    Indian journal of pediatrics, 2011, Volume: 78, Issue:1

    Topics: Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Diazepam; Female; Humans; Infant; Male

2011
Intermittent clobazam therapy in febrile seizures.
    Indian journal of pediatrics, 2005, Volume: 72, Issue:1

    Topics: Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Double-Blind Method; Female; Humans; I

2005

Other Studies

4 other studies available for clobazam and Seizures, Febrile

ArticleYear
Intermittent prophylaxis of recurrent febrile seizures with clobazam versus diazepam.
    Mymensingh medical journal : MMJ, 2014, Volume: 23, Issue:4

    Topics: Age Factors; Anticonvulsants; Ataxia; Bangladesh; Benzodiazepines; Chi-Square Distribution; Child, P

2014
[Study of an anxiolytic drug in infancy: clobazam].
    Annales de pediatrie, 1977, Volume: 24, Issue:5

    Topics: Anti-Anxiety Agents; Anxiety; Benzodiazepines; Clobazam; Dose-Response Relationship, Drug; Drug Admi

1977
Treatment of febrile seizures with intermittent clobazam.
    Arquivos de neuro-psiquiatria, 1997, Volume: 55, Issue:4

    Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Child; Child, Preschool; C

1997
Intermittent therapy with clobazam for simple febrile convulsions.
    Developmental medicine and child neurology, 1987, Volume: 29, Issue:6

    Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Child; Clobazam; Drug Admi

1987