clobazam has been researched along with Seizures, Febrile in 6 studies
Clobazam: A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
clobazam : 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substituted by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics.
Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)
Excerpt | Relevance | Reference |
---|---|---|
"Febrile seizures are the most common type of seizure among children that can be prevented by using prophylactic drugs like Clobazam and Diazepam." | 1.40 | Intermittent prophylaxis of recurrent febrile seizures with clobazam versus diazepam. ( Ahmed, AU; Banu, LA; Begum, SA; Haque, MA; Hoque, MR; Karim, MM; Momen, A; Parveen, F; Quddush, MR; Saha, SK; Sattar, S, 2014) |
"Clobazam was administered orally during the febrile episode according to the child's weight: up to 5 kg, 5 mg/day; from 5 to 10 kg, 10 mg/day; from 11 to 15 kg, 15 mg/day, and over 15 kg, 20 mg/day." | 1.30 | Treatment of febrile seizures with intermittent clobazam. ( Diament, A; Gherpelli, JL; Heise, CO; Machado-Haertel, LR; Manreza, ML; Pedreira, CC, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (33.33) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 2 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sattar, S | 1 |
Saha, SK | 1 |
Parveen, F | 1 |
Banu, LA | 1 |
Momen, A | 1 |
Ahmed, AU | 1 |
Quddush, MR | 1 |
Karim, MM | 1 |
Begum, SA | 1 |
Haque, MA | 1 |
Hoque, MR | 1 |
Khosroshahi, N | 1 |
Faramarzi, F | 1 |
Salamati, P | 1 |
Haghighi, SM | 1 |
Kamrani, K | 1 |
Rose, W | 1 |
Kirubakaran, C | 1 |
Scott, JX | 1 |
Guran, P | 1 |
Blanc, A | 1 |
Manreza, ML | 1 |
Gherpelli, JL | 1 |
Machado-Haertel, LR | 1 |
Pedreira, CC | 1 |
Heise, CO | 1 |
Diament, A | 1 |
Tondi, M | 1 |
Carboni, F | 1 |
Deriu, A | 1 |
Manca, S | 1 |
Mastropaolo, C | 1 |
2 trials available for clobazam and Seizures, Febrile
Article | Year |
---|---|
Diazepam versus clobazam for intermittent prophylaxis of febrile seizures.
Topics: Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Diazepam; Female; Humans; Infant; Male | 2011 |
Intermittent clobazam therapy in febrile seizures.
Topics: Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Double-Blind Method; Female; Humans; I | 2005 |
4 other studies available for clobazam and Seizures, Febrile
Article | Year |
---|---|
Intermittent prophylaxis of recurrent febrile seizures with clobazam versus diazepam.
Topics: Age Factors; Anticonvulsants; Ataxia; Bangladesh; Benzodiazepines; Chi-Square Distribution; Child, P | 2014 |
[Study of an anxiolytic drug in infancy: clobazam].
Topics: Anti-Anxiety Agents; Anxiety; Benzodiazepines; Clobazam; Dose-Response Relationship, Drug; Drug Admi | 1977 |
Treatment of febrile seizures with intermittent clobazam.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Child; Child, Preschool; C | 1997 |
Intermittent therapy with clobazam for simple febrile convulsions.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Child; Clobazam; Drug Admi | 1987 |