Page last updated: 2024-10-25

clobazam and Genetic Predisposition

clobazam has been researched along with Genetic Predisposition in 3 studies

Clobazam: A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
clobazam : 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substituted by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Citraro, R1
De Sarro, C1
Leo, A1
Donato di Paola, E1
Palma, E1
Russo, E1
De Sarro, G1
Cao, D1
Ohtani, H1
Ogiwara, I1
Ohtani, S1
Takahashi, Y1
Yamakawa, K1
Inoue, Y1
Kosaki, K1
Tamura, K1
Sato, R1
Samejima, H1
Tanigawara, Y1
Takahashi, T1

Other Studies

3 other studies available for clobazam and Genetic Predisposition

ArticleYear
Perampanel chronic treatment does not induce tolerance and decreases tolerance to clobazam in genetically epilepsy prone rats.
    Epilepsy research, 2018, Volume: 146

    Topics: Acoustic Stimulation; Administration, Oral; Animals; Anticonvulsants; Brain; Clobazam; Dose-Response

2018
Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.
    Epilepsia, 2012, Volume: 53, Issue:7

    Topics: Age Factors; Animals; Anticonvulsants; Benzodiazepines; Clobazam; Dioxolanes; Disease Models, Animal

2012
A major influence of CYP2C19 genotype on the steady-state concentration of N-desmethylclobazam.
    Brain & development, 2004, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Child; Child, Pr

2004