clobazam has been researched along with Genetic Predisposition in 3 studies
Clobazam: A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
clobazam : 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substituted by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Citraro, R | 1 |
| De Sarro, C | 1 |
| Leo, A | 1 |
| Donato di Paola, E | 1 |
| Palma, E | 1 |
| Russo, E | 1 |
| De Sarro, G | 1 |
| Cao, D | 1 |
| Ohtani, H | 1 |
| Ogiwara, I | 1 |
| Ohtani, S | 1 |
| Takahashi, Y | 1 |
| Yamakawa, K | 1 |
| Inoue, Y | 1 |
| Kosaki, K | 1 |
| Tamura, K | 1 |
| Sato, R | 1 |
| Samejima, H | 1 |
| Tanigawara, Y | 1 |
| Takahashi, T | 1 |
3 other studies available for clobazam and Genetic Predisposition
| Article | Year |
|---|---|
Perampanel chronic treatment does not induce tolerance and decreases tolerance to clobazam in genetically epilepsy prone rats.
Topics: Acoustic Stimulation; Administration, Oral; Animals; Anticonvulsants; Brain; Clobazam; Dose-Response | 2018 |
Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.
Topics: Age Factors; Animals; Anticonvulsants; Benzodiazepines; Clobazam; Dioxolanes; Disease Models, Animal | 2012 |
A major influence of CYP2C19 genotype on the steady-state concentration of N-desmethylclobazam.
Topics: Adolescent; Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Child; Child, Pr | 2004 |