clobazam has been researched along with Body Weight in 4 studies
Clobazam: A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
clobazam : 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substituted by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clobazam (CLB) is a 1,5-benzodiazepine with antiepileptic properties." | 5.40 | Effects of CYP2C19 and P450 oxidoreductase polymorphisms on the population pharmacokinetics of clobazam and N-desmethylclobazam in japanese patients with epilepsy. ( Ishitsu, T; Kaneko, S; Nagata, R; Nakagawa, K; Nakashima, H; Nishimura, M; Ogusu, N; Saruwatari, J; Seo, T; Shimomasuda, M; Tanikawa, K; Tsuda, Y; Yasui-Furukori, N, 2014) |
| "The alterations observed in body composition with valproic acid in contrast to other AEDs like levetiracetam, carbamazepine and phenytoin could affect treatment response in epilepsy especially in subjects with already altered body composition status like obese and thin frail patients, which needs to be established by prospective studies (CTRI/2013/05/003701)." | 3.83 | Comparison of body composition in persons with epilepsy on conventional & new antiepileptic drugs. ( Gupta, YK; Kakkar, AK; Sarangi, SC; Tripathi, M, 2016) |
| "Thirty-five children with epilepsy were included in a prospective population pharmacokinetic study (using NONMEM(®) software)." | 1.42 | Pharmacokinetics of clobazam and N-desmethylclobazam in children with dravet syndrome receiving concomitant stiripentol and valproic Acid. ( Chhun, S; Chiron, C; Dulac, O; Jullien, V; Pons, G; Rey, E; Tod, M, 2015) |
| "Clobazam (CLB) is a 1,5-benzodiazepine with antiepileptic properties." | 1.40 | Effects of CYP2C19 and P450 oxidoreductase polymorphisms on the population pharmacokinetics of clobazam and N-desmethylclobazam in japanese patients with epilepsy. ( Ishitsu, T; Kaneko, S; Nagata, R; Nakagawa, K; Nakashima, H; Nishimura, M; Ogusu, N; Saruwatari, J; Seo, T; Shimomasuda, M; Tanikawa, K; Tsuda, Y; Yasui-Furukori, N, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galappatthy, P | 1 |
| Liyanage, CK | 1 |
| Lucas, MN | 1 |
| Jayasekara, DTLM | 1 |
| Abhayaratna, SA | 1 |
| Weeraratne, C | 1 |
| De Abrew, K | 1 |
| Gunaratne, PS | 1 |
| Gamage, R | 1 |
| Wijeyaratne, CN | 1 |
| Saruwatari, J | 1 |
| Ogusu, N | 1 |
| Shimomasuda, M | 1 |
| Nakashima, H | 1 |
| Seo, T | 1 |
| Tanikawa, K | 1 |
| Tsuda, Y | 1 |
| Nishimura, M | 1 |
| Nagata, R | 1 |
| Yasui-Furukori, N | 1 |
| Kaneko, S | 1 |
| Ishitsu, T | 1 |
| Nakagawa, K | 1 |
| Jullien, V | 1 |
| Chhun, S | 1 |
| Rey, E | 1 |
| Dulac, O | 1 |
| Tod, M | 1 |
| Chiron, C | 1 |
| Pons, G | 1 |
| Sarangi, SC | 1 |
| Tripathi, M | 1 |
| Kakkar, AK | 1 |
| Gupta, YK | 1 |
4 other studies available for clobazam and Body Weight
| Article | Year |
|---|---|
Obstetric outcomes and effects on babies born to women treated for epilepsy during pregnancy in a resource limited setting: a comparative cohort study.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anticonvulsants; Body Height; Body Weight; Carbamazepine; | 2018 |
Effects of CYP2C19 and P450 oxidoreductase polymorphisms on the population pharmacokinetics of clobazam and N-desmethylclobazam in japanese patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Body Weight; Child; Child, Preschool; Clobazam; | 2014 |
Pharmacokinetics of clobazam and N-desmethylclobazam in children with dravet syndrome receiving concomitant stiripentol and valproic Acid.
Topics: Anticonvulsants; Benzodiazepines; Body Weight; Child; Child, Preschool; Clobazam; Dioxolanes; Drug I | 2015 |
Comparison of body composition in persons with epilepsy on conventional & new antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Body Composition; Body Water; Body Weight; Carbamazepine; C | 2016 |