Page last updated: 2024-10-25

clioquinol and Precancerous Conditions

clioquinol has been researched along with Precancerous Conditions in 2 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research Excerpts

ExcerptRelevanceReference
" In the current study, we investigate whether clioquinol (CQ), an analog of 8-hydroxyquinoline and an Alzheimer's disease drug, and pyrrolidine dithiocarbamate (PDTC), a known copper-binding compound and antioxidant, can interact with copper to form cancer-specific proteasome inhibitors and apoptosis inducers in human breast cancer cells."7.73Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells. ( Chen, D; Cui, QC; Daniel, KG; Dou, QP; Miller, FR; Orlu, S, 2005)
" In the current study, we investigate whether clioquinol (CQ), an analog of 8-hydroxyquinoline and an Alzheimer's disease drug, and pyrrolidine dithiocarbamate (PDTC), a known copper-binding compound and antioxidant, can interact with copper to form cancer-specific proteasome inhibitors and apoptosis inducers in human breast cancer cells."3.73Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells. ( Chen, D; Cui, QC; Daniel, KG; Dou, QP; Miller, FR; Orlu, S, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daniel, KG1
Chen, D1
Orlu, S1
Cui, QC1
Miller, FR1
Dou, QP1
Katz, H1
Redding, KG1

Other Studies

2 other studies available for clioquinol and Precancerous Conditions

ArticleYear
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.
    Breast cancer research : BCR, 2005, Volume: 7, Issue:6

    Topics: Anti-Infective Agents, Local; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Prol

2005
Therapeutic challenge of premalignant and malignant skin lesions.
    Geriatrics, 1975, Volume: 30, Issue:3

    Topics: Acetates; Adrenal Cortex Hormones; Adult; Aged; Balanitis; Bowen's Disease; Clioquinol; Cryosurgery;

1975
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