Page last updated: 2024-10-25

clioquinol and Pneumonia

clioquinol has been researched along with Pneumonia in 2 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multidrug-resistance exceeding 80% and 40%, respectively."5.72Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model. ( Bohlmann, L; Brazel, EB; Cunningham, BA; De Oliveira, DMP; Eijkelkamp, BA; El-Deeb, IM; Ganio, K; Iverson, AR; Keller, B; Maher, MJ; McDevitt, CA; McEwan, AG; Neville, SL; Rosch, JW; Sikanyika, M; Tan, A; Udagedara, SR; von Itzstein, M; Walker, MJ, 2022)
"Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multidrug-resistance exceeding 80% and 40%, respectively."1.72Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model. ( Bohlmann, L; Brazel, EB; Cunningham, BA; De Oliveira, DMP; Eijkelkamp, BA; El-Deeb, IM; Ganio, K; Iverson, AR; Keller, B; Maher, MJ; McDevitt, CA; McEwan, AG; Neville, SL; Rosch, JW; Sikanyika, M; Tan, A; Udagedara, SR; von Itzstein, M; Walker, MJ, 2022)
" fumigatus In vitro both chelators had an indifferent effect when employed in combination with caspofungin."1.43Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin. ( Atrouni, A; Calera, JA; Cavaillon, JM; d'Enfert, C; Ibrahim-Granet, O; Laskaris, P; Latgé, JP; Munier-Lehmann, H, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Brazel, EB1
Tan, A1
Neville, SL1
Iverson, AR1
Udagedara, SR1
Cunningham, BA1
Sikanyika, M1
De Oliveira, DMP1
Keller, B1
Bohlmann, L1
El-Deeb, IM1
Ganio, K1
Eijkelkamp, BA1
McEwan, AG1
von Itzstein, M1
Maher, MJ1
Walker, MJ1
Rosch, JW1
McDevitt, CA1
Laskaris, P1
Atrouni, A1
Calera, JA1
d'Enfert, C1
Munier-Lehmann, H1
Cavaillon, JM1
Latgé, JP1
Ibrahim-Granet, O1

Other Studies

2 other studies available for clioquinol and Pneumonia

ArticleYear
Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model.
    Cell reports, 2022, 01-11, Volume: 38, Issue:2

    Topics: Ampicillin; Ampicillin Resistance; Animals; Anti-Bacterial Agents; Clioquinol; Disease Models, Anima

2022
Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:10

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Caspofungin; Chelating Agents; Cli

2016