clioquinol has been researched along with Pneumonia in 2 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Pneumonia: Infection of the lung often accompanied by inflammation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multidrug-resistance exceeding 80% and 40%, respectively." | 5.72 | Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model. ( Bohlmann, L; Brazel, EB; Cunningham, BA; De Oliveira, DMP; Eijkelkamp, BA; El-Deeb, IM; Ganio, K; Iverson, AR; Keller, B; Maher, MJ; McDevitt, CA; McEwan, AG; Neville, SL; Rosch, JW; Sikanyika, M; Tan, A; Udagedara, SR; von Itzstein, M; Walker, MJ, 2022) |
| "Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multidrug-resistance exceeding 80% and 40%, respectively." | 1.72 | Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model. ( Bohlmann, L; Brazel, EB; Cunningham, BA; De Oliveira, DMP; Eijkelkamp, BA; El-Deeb, IM; Ganio, K; Iverson, AR; Keller, B; Maher, MJ; McDevitt, CA; McEwan, AG; Neville, SL; Rosch, JW; Sikanyika, M; Tan, A; Udagedara, SR; von Itzstein, M; Walker, MJ, 2022) |
| " fumigatus In vitro both chelators had an indifferent effect when employed in combination with caspofungin." | 1.43 | Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin. ( Atrouni, A; Calera, JA; Cavaillon, JM; d'Enfert, C; Ibrahim-Granet, O; Laskaris, P; Latgé, JP; Munier-Lehmann, H, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brazel, EB | 1 |
| Tan, A | 1 |
| Neville, SL | 1 |
| Iverson, AR | 1 |
| Udagedara, SR | 1 |
| Cunningham, BA | 1 |
| Sikanyika, M | 1 |
| De Oliveira, DMP | 1 |
| Keller, B | 1 |
| Bohlmann, L | 1 |
| El-Deeb, IM | 1 |
| Ganio, K | 1 |
| Eijkelkamp, BA | 1 |
| McEwan, AG | 1 |
| von Itzstein, M | 1 |
| Maher, MJ | 1 |
| Walker, MJ | 1 |
| Rosch, JW | 1 |
| McDevitt, CA | 1 |
| Laskaris, P | 1 |
| Atrouni, A | 1 |
| Calera, JA | 1 |
| d'Enfert, C | 1 |
| Munier-Lehmann, H | 1 |
| Cavaillon, JM | 1 |
| Latgé, JP | 1 |
| Ibrahim-Granet, O | 1 |
2 other studies available for clioquinol and Pneumonia
| Article | Year |
|---|---|
Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model.
Topics: Ampicillin; Ampicillin Resistance; Animals; Anti-Bacterial Agents; Clioquinol; Disease Models, Anima | 2022 |
Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Caspofungin; Chelating Agents; Cli | 2016 |