Page last updated: 2024-10-25

clioquinol and Focal Neurologic Deficits

clioquinol has been researched along with Focal Neurologic Deficits in 7 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KUSUI, K1
YATAKA, I1
OKAMOTO, M1
NISHIKAWA, T1
KAMIDE, M1
Osterman, PO1
Selby, G1
Nelson, E1
Cambier, J1
Masson, M1
Berkman, N1
Dairou, R1
Oakley, GP1
Terry, SI1

Other Studies

7 other studies available for clioquinol and Focal Neurologic Deficits

ArticleYear
[Clinical observations on ulcerative colitis, with special reference to 3 cases showing severe nervous symptoms during the course of the disease].
    Naika. Internal medicine, 1963, Volume: 11

    Topics: Biological Products; Chloramphenicol; Clioquinol; Colitis; Colitis, Ulcerative; Humans; Neurologic M

1963
Myelopathy after clioquinol treatment.
    Lancet (London, England), 1971, Sep-04, Volume: 2, Issue:7723

    Topics: Abdomen; Adult; Clioquinol; Humans; Male; Myelitis; Nervous System Diseases; Neurologic Manifestatio

1971
Subacute myelo-optic neuropathy in Australia.
    Lancet (London, England), 1972, Jan-15, Volume: 1, Issue:7742

    Topics: Abdomen; Aged; Australia; Clioquinol; Diarrhea; Female; Humans; Male; Middle Aged; Myelitis; Neurolo

1972
Subacute myelo-optico-neuropathy (SMON).
    Annals of internal medicine, 1972, Volume: 77, Issue:3

    Topics: Abdomen; Clioquinol; Humans; Japan; Myelitis; Neurologic Manifestations; Optic Neuritis; Pain

1972
[Sensory neuropathy and optic neuritis after prolonged absorption of chloroidoquinone].
    La Nouvelle presse medicale, 1972, Aug-26, Volume: 1, Issue:30

    Topics: Aged; Clioquinol; Extremities; Female; Humans; Neuritis; Neurologic Manifestations; Optic Neuritis;

1972
The neurotoxicity of the halogenated hydroxyquinolines. A commentary.
    JAMA, 1973, Jul-23, Volume: 225, Issue:4

    Topics: Abdomen; Anti-Infective Agents; Central Nervous System; Chlorquinaldol; Clioquinol; Disease Outbreak

1973
Transient dysaesthesiae and persistent leucocytosis after clioquinol therapy.
    British medical journal, 1971, Sep-25, Volume: 3, Issue:5777

    Topics: Adult; Anti-Infective Agents, Local; Arm; Ascaris; Blood Cell Count; Clioquinol; Diarrhea; Face; Fec

1971