Page last updated: 2024-10-25

clioquinol and Depressive Disorder, Major

clioquinol has been researched along with Depressive Disorder, Major in 1 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research Excerpts

ExcerptRelevanceReference
"The prevalence of major depressive disorder in SMON patients was estimated by structured interview and using Beck's depression inventory (BDI) questionnaires."1.35Depression in patients with subacute myelo-optico-neuropathy (SMON). ( Fujimura, H; Funakawa, I; Hayashi, K; Hayashi, M; Kaido, M; Konishi, T; Ueno, S; Yoshida, S, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Konishi, T1
Hayashi, K1
Hayashi, M1
Ueno, S1
Yoshida, S1
Fujimura, H1
Funakawa, I1
Kaido, M1

Other Studies

1 other study available for clioquinol and Depressive Disorder, Major

ArticleYear
Depression in patients with subacute myelo-optico-neuropathy (SMON).
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:24

    Topics: Aged; Aged, 80 and over; Clioquinol; Depressive Disorder, Major; Female; Humans; Male; Middle Aged;

2008