clioquinol has been researched along with Depressive Disorder, Major in 1 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
Excerpt | Relevance | Reference |
---|---|---|
"The prevalence of major depressive disorder in SMON patients was estimated by structured interview and using Beck's depression inventory (BDI) questionnaires." | 1.35 | Depression in patients with subacute myelo-optico-neuropathy (SMON). ( Fujimura, H; Funakawa, I; Hayashi, K; Hayashi, M; Kaido, M; Konishi, T; Ueno, S; Yoshida, S, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Konishi, T | 1 |
Hayashi, K | 1 |
Hayashi, M | 1 |
Ueno, S | 1 |
Yoshida, S | 1 |
Fujimura, H | 1 |
Funakawa, I | 1 |
Kaido, M | 1 |
1 other study available for clioquinol and Depressive Disorder, Major
Article | Year |
---|---|
Depression in patients with subacute myelo-optico-neuropathy (SMON).
Topics: Aged; Aged, 80 and over; Clioquinol; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; | 2008 |