clioquinol has been researched along with Dementia in 4 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study investigates the anti-amnesic potential of clioquinol (5-chloro-7-iodoquinolin-8-ol) in cognitive deficits associated with experimental dementia induced by Cu-Ch." | 7.81 | Memory restorative ability of clioquinol in copper-cholesterol-induced experimental dementia in mice. ( Aggarwal, N; Mehra, R; Sodhi, RK, 2015) |
| "The present study investigates the anti-amnesic potential of clioquinol (5-chloro-7-iodoquinolin-8-ol) in cognitive deficits associated with experimental dementia induced by Cu-Ch." | 3.81 | Memory restorative ability of clioquinol in copper-cholesterol-induced experimental dementia in mice. ( Aggarwal, N; Mehra, R; Sodhi, RK, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lei, P | 1 |
| Ayton, S | 1 |
| Appukuttan, AT | 1 |
| Volitakis, I | 1 |
| Adlard, PA | 1 |
| Finkelstein, DI | 1 |
| Bush, AI | 1 |
| Mehra, R | 1 |
| Sodhi, RK | 1 |
| Aggarwal, N | 1 |
| Saito, Y | 1 |
| Sakai, K | 1 |
| Konagaya, M | 1 |
| Yoshioka, M | 1 |
| Nakanishi, T | 1 |
1 review available for clioquinol and Dementia
| Article | Year |
|---|---|
[Oxidative precipitation of transthyretin--a clue to elucidate amyloidosis].
Topics: Amyloidosis; Chemical Precipitation; Clioquinol; Dementia; Humans; Oxidation-Reduction; Prealbumin | 2008 |
3 other studies available for clioquinol and Dementia
| Article | Year |
|---|---|
Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Clioquinol; Dementia; Disease Models, Animal; Dopami | 2015 |
Memory restorative ability of clioquinol in copper-cholesterol-induced experimental dementia in mice.
Topics: Acetylcholinesterase; Animals; Anticholesteremic Agents; Antioxidants; Behavior, Animal; Biomarkers; | 2015 |
The prevalence of dementia in subacute myelo-optico-neuropathy (SMON) patients who underwent medical checkups.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Infective Agents; Clioquinol; Dementia; Female; Hum | 2016 |