clioquinol has been researched along with Chronic Disease in 19 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Primary: to compare one-off administration of boric acid powder with courses of 1% acetic acid and ciprofloxacin eardrops in treating active chronic otitis media." | 5.16 | A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings. ( Loock, JW, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (78.95) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Jong, MJ | 1 |
| Korterink, JJ | 1 |
| Benninga, MA | 1 |
| Hilbink, M | 1 |
| Widdershoven, J | 1 |
| Deckers-Kocken, JM | 1 |
| Loock, JW | 1 |
| RITTINGHAUS, FW | 1 |
| Yamanaka, Y | 1 |
| Asahina, M | 1 |
| Akaogi, Y | 1 |
| Koyama, Y | 1 |
| Hattori, T | 1 |
| Minder, HP | 1 |
| Merritt, AM | 1 |
| Chalupa, W | 1 |
| Datsun, TA | 1 |
| Tateishi, J | 1 |
| Otsuki, S | 1 |
| Rivara, G | 1 |
| Barile, M | 1 |
| Guarrera, M | 1 |
| Karnaukhov, VK | 1 |
| Gjone, E | 1 |
| Brodnig, V | 1 |
| Manahan, FF | 1 |
| Papuziński, M | 1 |
| Zalewski, T | 1 |
| Pedersen, KK | 1 |
| Christiansen, N | 1 |
| Men'shikov, FK | 1 |
| Khar'kovskiĭ, NN | 1 |
| Morozov, KA | 1 |
| Valenkevich, LN | 1 |
2 trials available for clioquinol and Chronic Disease
| Article | Year |
|---|---|
A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings.
Topics: Acetic Acid; Administration, Topical; Adult; Analysis of Variance; Anti-Infective Agents; Audiometry | 2012 |
Effects of a vioform-entobex preparation (Mexaform) on patients with chronic constipation.
Topics: Adolescent; Adult; Chronic Disease; Clinical Trials as Topic; Clioquinol; Constipation; Female; Huma | 1967 |
17 other studies available for clioquinol and Chronic Disease
| Article | Year |
|---|---|
Dientamoeba fragilis and chronic abdominal pain in children: a case-control study.
Topics: Abdominal Pain; Adolescent; Antiprotozoal Agents; Case-Control Studies; Child; Chronic Disease; Clio | 2014 |
CHRONIC otitis externa.
Topics: Chronic Disease; Clioquinol; Humans; Otitis Externa; Quinolines; Uricosuric Agents | 1953 |
[CONTRIBUTION TO THE THERAPY OF CHRONIC INTESTINAL DISORDERS].
Topics: Chronic Disease; Clioquinol; Constipation; Defecation; Flatulence; Humans; Intestinal Diseases; Inte | 1963 |
Diminished skin vasodilator response to local heating in patients with long-standingsubacute myelo-optico-neuropathy.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Autonomic Dysreflexia; Autonomic Nervous System Dise | 2007 |
In vitro fermentation of feces from normal and chronically diarrheal horses.
Topics: Amino Acids, Essential; Animals; Chronic Disease; Clioquinol; Diarrhea; Fatty Acids, Volatile; Feces | 1980 |
[Use of nerobol and mexase in combination with mineral water from Morshin health resort in chronic colitis].
Topics: Adolescent; Adult; Aged; Bromelains; Chronic Disease; Clioquinol; Colitis; Dehydrocholic Acid; Drug | 1976 |
Experimental reproduction of SMON in animals by prolonged administration of clioquinol: clinico-pathological findings.
Topics: Acute Disease; Animals; Cats; Chronic Disease; Clioquinol; Dogs; Haplorhini; Kidney; Liver; Male; Mi | 1975 |
Photosensitivity in a patient with contact allergic dermatitis from clioquinol.
Topics: Chronic Disease; Clioquinol; Dermatitis, Contact; Humans; Male; Middle Aged; Patch Tests; Photosensi | 1991 |
[Experience in the treatment of nonspecific ulcerative colitis].
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Bacterial Agents; Child; Child | 1973 |
[Chronic obstipation and other intestinal disorders in women and their therapy].
Topics: Adolescent; Adult; Aged; Chronic Disease; Clioquinol; Constipation; Diagnosis, Differential; Female; | 1968 |
Diarrhoea in horses with particular reference to a chronic diarrhoea syndrome.
Topics: Animals; Anti-Bacterial Agents; Australia; Balantidium; Chronic Disease; Clioquinol; Diarrhea; Esche | 1970 |
[Acrodermatitis enteropathica].
Topics: Acrodermatitis; Alopecia; Child; Child, Preschool; Chronic Disease; Clioquinol; Diarrhea; Female; Fo | 1971 |
[Acute and chronic clioquinol intoxication].
Topics: Acute Disease; Adult; Chronic Disease; Clioquinol; Female; Humans; Optic Neuritis | 1972 |
[Use of the preparation Mekcase in chronic enterocolitis].
Topics: Adult; Bromelains; Chronic Disease; Clioquinol; Colitis; Drug Combinations; Enteritis; Female; Gastr | 1972 |
[Therapeutic effectiveness of mexaform, mexase and festal in chronic enterocolitis].
Topics: Bromelains; Chronic Disease; Clioquinol; Colitis; Dehydrocholic Acid; Drug Combinations; Drug Therap | 1974 |
Warning on diiodohydroxyquin.
Topics: Abdomen; Acrodermatitis; Adult; Age Factors; Amebiasis; Child, Preschool; Chronic Disease; Clioquino | 1974 |
Management of patients with vaginal infections. An invitational symposium.
Topics: Adult; Candidiasis, Vulvovaginal; Child; Chronic Disease; Clioquinol; Estrogens, Conjugated (USP); F | 1972 |