clioquinol has been researched along with Central Nervous System Disease in 5 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baumgartner, G | 1 |
| Gilland, O | 1 |
| Kaeser, HE | 2 |
| Pallis, CA | 2 |
| Rose, FC | 2 |
| Schaumburg, HH | 2 |
| Thomas, PK | 2 |
| Wadia, NH | 2 |
| Spencer, PS | 1 |
| Le Quesne, PM | 1 |
| Tateishi, J | 1 |
| Kuroda, S | 1 |
| Saito, A | 1 |
| Otsuki, S | 1 |
1 review available for clioquinol and Central Nervous System Disease
| Article | Year |
|---|---|
Neurotoxic substances.
Topics: Acrylamides; Animals; Cats; Central Nervous System Diseases; Clioquinol; Environmental Exposure; Hex | 1975 |
4 other studies available for clioquinol and Central Nervous System Disease
| Article | Year |
|---|---|
Neurotoxicity of halogenated hydroxyquinolines.
Topics: Central Nervous System; Central Nervous System Diseases; Clioquinol; Humans; Hydroxyquinolines | 1984 |
Central distal axonopathy syndromes: newly recognized models of naturally occurring human degenerative disease.
Topics: Animals; Axons; Central Nervous System Diseases; Clioquinol; Disease Models, Animal; Dogs; Humans; L | 1984 |
Clioquinol and related drugs.
Topics: Central Nervous System Diseases; Clioquinol; Hydroxyquinolines; Male | 1979 |
Experimental myelo-optic neuropathy induced by clioquinol.
Topics: Animals; Ataxia; Autopsy; Axons; Brain; Cats; Central Nervous System Diseases; Clioquinol; Demyelina | 1973 |