clioquinol has been researched along with Cancer of Prostate in 4 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clioquinol treatment caused cytoplasmic XIAP to rapidly relocate to the nucleus in multiple human transformed (hyperplasic and carcinoma) prostate lines." | 1.37 | Clioquinol induces cytoplasmic clearance of the X-linked inhibitor of apoptosis protein (XIAP): therapeutic indication for prostate cancer. ( Cater, MA; Haupt, Y, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barrea, RA | 2 |
| Chen, D | 2 |
| Irving, TC | 1 |
| Dou, QP | 2 |
| Yu, H | 1 |
| Lou, JR | 1 |
| Ding, WQ | 1 |
| Cater, MA | 1 |
| Haupt, Y | 1 |
| Cui, QC | 1 |
| Yang, H | 1 |
| Sarkar, FH | 1 |
| Sheng, S | 1 |
| Yan, B | 1 |
| Reddy, GP | 1 |
4 other studies available for clioquinol and Cancer of Prostate
| Article | Year |
|---|---|
Synchrotron X-ray imaging reveals a correlation of tumor copper speciation with Clioquinol's anticancer activity.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Clioquinol; Copper; Diagnostic Imaging; Male; Mice | 2009 |
Clioquinol independently targets NF-kappaB and lysosome pathways in human cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Membrane Permeability; Clioquinol; Humans; Leupeptins; | 2010 |
Clioquinol induces cytoplasmic clearance of the X-linked inhibitor of apoptosis protein (XIAP): therapeutic indication for prostate cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Clioquinol; Humans; Male; P | 2011 |
Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts.
Topics: Androgen Receptor Antagonists; Animals; Apoptosis; Cell Line, Tumor; Clioquinol; Copper; Humans; Mal | 2007 |