clioquinol has been researched along with Breast Neoplasms in 2 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the current study, we investigate whether clioquinol (CQ), an analog of 8-hydroxyquinoline and an Alzheimer's disease drug, and pyrrolidine dithiocarbamate (PDTC), a known copper-binding compound and antioxidant, can interact with copper to form cancer-specific proteasome inhibitors and apoptosis inducers in human breast cancer cells." | 7.73 | Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells. ( Chen, D; Cui, QC; Daniel, KG; Dou, QP; Miller, FR; Orlu, S, 2005) |
| " This study investigated the effects of clioquinol on cyclin D1 gene expression in breast cancer cells." | 3.77 | Clioquinol suppresses cyclin D1 gene expression through transcriptional and post-transcriptional mechanisms. ( Benbrook, DM; Ding, WQ; Yu, H; Zheng, J, 2011) |
| " In the current study, we investigate whether clioquinol (CQ), an analog of 8-hydroxyquinoline and an Alzheimer's disease drug, and pyrrolidine dithiocarbamate (PDTC), a known copper-binding compound and antioxidant, can interact with copper to form cancer-specific proteasome inhibitors and apoptosis inducers in human breast cancer cells." | 3.73 | Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells. ( Chen, D; Cui, QC; Daniel, KG; Dou, QP; Miller, FR; Orlu, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, J | 1 |
| Benbrook, DM | 1 |
| Yu, H | 1 |
| Ding, WQ | 1 |
| Daniel, KG | 1 |
| Chen, D | 1 |
| Orlu, S | 1 |
| Cui, QC | 1 |
| Miller, FR | 1 |
| Dou, QP | 1 |
2 other studies available for clioquinol and Breast Neoplasms
| Article | Year |
|---|---|
Clioquinol suppresses cyclin D1 gene expression through transcriptional and post-transcriptional mechanisms.
Topics: 3' Untranslated Regions; Antineoplastic Agents; Base Sequence; Breast Neoplasms; Cell Line, Tumor; C | 2011 |
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.
Topics: Anti-Infective Agents, Local; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Prol | 2005 |