clioquinol has been researched along with Brain Injuries in 2 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, BY | 1 |
| Kim, JH | 1 |
| Kim, HJ | 1 |
| Lee, BE | 1 |
| Kim, IY | 1 |
| Sohn, M | 1 |
| Suh, SW | 1 |
| Tateishi, J | 1 |
1 review available for clioquinol and Brain Injuries
| Article | Year |
|---|---|
Subacute myelo-optico-neuropathy: clioquinol intoxication in humans and animals.
Topics: Animals; Brain Injuries; Clioquinol; Diagnosis, Differential; Disease Models, Animal; Humans; Japan; | 2000 |
1 other study available for clioquinol and Brain Injuries
| Article | Year |
|---|---|
Zinc chelation reduces traumatic brain injury-induced neurogenesis in the subgranular zone of the hippocampal dentate gyrus.
Topics: Animals; Brain Injuries; Clioquinol; Dentate Gyrus; Doublecortin Protein; Hippocampus; Immunohistoch | 2014 |