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clioquinol and Brain Disorders

clioquinol has been researched along with Brain Disorders in 7 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Research Excerpts

ExcerptRelevanceReference
"They resemble transient global amnesia (TGA) of the classic type, but the episodes last longer (1-3 days), they are often accompanied by a variety of mental disturbances, and the onset and end are less well defined than in the classic type."6.37Transient global amnesia due to clioquinol. ( Kaeser, HE, 1984)
"They resemble transient global amnesia (TGA) of the classic type, but the episodes last longer (1-3 days), they are often accompanied by a variety of mental disturbances, and the onset and end are less well defined than in the classic type."2.37Transient global amnesia due to clioquinol. ( Kaeser, HE, 1984)
" The onset of all manifestations (except toxic encephalopathy) was usually subacute, with subsequent partial recovery."1.26Neurotoxicity of halogenated hydroxyquinolines: clinical analysis of cases reported outside Japan. ( Baumgartner, G; Gawel, MJ; Kaeser, HE; Pallis, CA; Rose, FC; Schaumburg, HH; Thomas, PK; Wadia, NH, 1979)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pollera, C1
Lucchini, B1
Formentin, E1
Bareggi, S1
Poli, G1
Ponti, W1
Kaeser, HE2
Buchanan, DS1
Krinke, G1
Schaumburg, HH2
Spencer, PS1
Thomann, P1
Hess, R1
Baumgartner, G1
Gawel, MJ1
Pallis, CA1
Rose, FC1
Thomas, PK1
Wadia, NH1
Ferrier, TM1
Eadie, MJ1

Reviews

1 review available for clioquinol and Brain Disorders

ArticleYear
Transient global amnesia due to clioquinol.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 100

    Topics: Acute Disease; Adult; Aged; Amnesia; Amnesia, Retrograde; Brain Diseases; Clioquinol; Confusion; Fem

1984

Other Studies

6 other studies available for clioquinol and Brain Disorders

ArticleYear
Evaluation of anti-prionic activity of clioquinol in an in vivo model (Mesocricetus auratus).
    Veterinary research communications, 2005, Volume: 29 Suppl 2

    Topics: Animals; Anti-Infective Agents; Brain Diseases; Central Nervous System; Clioquinol; Cricetinae; Dise

2005
Idiosyncratic neurotoxicity: clioquinol and bismuth.
    Lancet (London, England), 1980, Apr-19, Volume: 1, Issue:8173

    Topics: Austria; Bismuth; Brain Diseases; Clioquinol; Dose-Response Relationship, Drug; France; Humans; Japa

1980
Iatrogenic causes of neurologic disorders: part 1. Affect, convulsions, and encephalopathies.
    Geriatrics, 1978, Volume: 33, Issue:8

    Topics: Affective Symptoms; Aged; Antiparkinson Agents; Brain Diseases; Clioquinol; Cognition Disorders; Hum

1978
Clioquinol and 2,5-hexanedione induce different types of distal axonopathy in the dog.
    Acta neuropathologica, 1979, Volume: 47, Issue:3

    Topics: Animals; Axons; Brain; Brain Diseases; Clioquinol; Dogs; Ketones; Methyl n-Butyl Ketone; Microscopy,

1979
Neurotoxicity of halogenated hydroxyquinolines: clinical analysis of cases reported outside Japan.
    Journal of neurology, neurosurgery, and psychiatry, 1979, Volume: 42, Issue:12

    Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Child, Preschool; Clioquinol; Dose-Response Relation

1979
Clioquinol encephalopathy.
    The Medical journal of Australia, 1973, Dec-01, Volume: 2, Issue:22

    Topics: Adult; Brain Diseases; Clioquinol; Cognition Disorders; Female; Headache; Humans; Male; Memory Disor

1973