clioquinol has been researched along with Bone Loss, Osteoclastic in 1 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients of Alzheimer's disease (AD) frequently have lower bone mineral density and higher rate of hip fracture." | 1.42 | Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer's Disease. ( Cui, S; Guo, JP; Pan, JX; Xia, WF; Xiong, L; Xiong, WC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, JP | 1 |
| Pan, JX | 1 |
| Xiong, L | 1 |
| Xia, WF | 1 |
| Cui, S | 1 |
| Xiong, WC | 1 |
1 other study available for clioquinol and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Bone Resorption; Cation Transport Proteins; Cell Differentiation; Cells, | 2015 |