Page last updated: 2024-10-25

clioquinol and Bacterial Disease

clioquinol has been researched along with Bacterial Disease in 3 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Research Excerpts

ExcerptRelevanceReference
" In the first trial, long-term residents of Mexico with acute fecal leukocyte-positive diarrhea were randomized to receive trimethoprim/sulfamethoxazole (TMP/SMX), clioquinol or a placebo."5.07Antimicrobial therapy of bacterial diarrhea in adult residents of Mexico--lack of an effect. ( de la Cabada, FJ; DuPont, HL; Gyr, K; Mathewson, JJ, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stickler, GB1
de la Cabada, FJ1
DuPont, HL1
Gyr, K1
Mathewson, JJ1
Carpenter, CL1
Jolly, HW1
McCormick, GE1
Schneiderman, RN1
Thompson, JG1

Trials

2 trials available for clioquinol and Bacterial Disease

ArticleYear
Antimicrobial therapy of bacterial diarrhea in adult residents of Mexico--lack of an effect.
    Digestion, 1992, Volume: 53, Issue:3-4

    Topics: Adult; Bacterial Infections; Clioquinol; Diarrhea; Double-Blind Method; Enoxacin; Female; Humans; Ma

1992
Combined steroid-antiinfective topical therapy in common dermatoses: a double-blind, multi-center study of iodochlorhydroxyquin-hydrocortisone in 277 patients.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Infections; Child; Child, Preschool

1973

Other Studies

1 other study available for clioquinol and Bacterial Disease

ArticleYear
Simple therapy for simple diseases, here as well as abroad.
    Clinical pediatrics, 1975, Volume: 14, Issue:12

    Topics: Anti-Bacterial Agents; Bacterial Infections; Child; Clioquinol; Diarrhea; Drug Therapy; Drug-Related

1975