clioquinol has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 2 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lei, P | 1 |
| Ayton, S | 1 |
| Appukuttan, AT | 1 |
| Volitakis, I | 2 |
| Adlard, PA | 2 |
| Finkelstein, DI | 2 |
| Bush, AI | 2 |
| Billings, JL | 1 |
| Hare, DJ | 1 |
| Nurjono, M | 1 |
| Cherny, RA | 1 |
2 other studies available for clioquinol and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Clioquinol; Dementia; Disease Models, Animal; Dopami | 2015 |
Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse.
Topics: Animals; Animals, Newborn; Clioquinol; Disease Models, Animal; Humans; Iron; Iron Chelating Agents; | 2016 |