clioquinol has been researched along with Amaurosis in 6 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Those patients with complete or near complete blindness were profoundly handicapped so that the ratio of patients with a life-long institutionalization was high compared to the groups with less severe visual disturbance." | 1.31 | [Analysis of SMON at 30 years after its outbreak ending: special reference to those patients with blindness]. ( Iwashita, H; Konagaya, M; Matsuoka, Y; Nakae, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cahoon, L | 1 |
| Konagaya, M | 2 |
| Matsuoka, Y | 2 |
| Nakae, K | 1 |
| Iwashita, H | 2 |
| Matsumoto, A | 1 |
| Takase, S | 1 |
| Mizutani, T | 1 |
| Sobue, G | 1 |
| Konishi, T | 1 |
| Hayabara, T | 1 |
| Ujihira, T | 1 |
| Miyata, K | 1 |
| Garcia-Perez, A | 1 |
| Castro, C | 1 |
| Franco, A | 1 |
| Escribano, R | 1 |
1 trial available for clioquinol and Amaurosis
| Article | Year |
|---|---|
Blindness and neuropathy from diiodohydroxyquin-like drugs. Committee on drugs.
Topics: Acrodermatitis; Amebiasis; Blindness; Child; Chlorquinaldol; Clioquinol; Diarrhea; Dose-Response Rel | 1974 |
5 other studies available for clioquinol and Amaurosis
| Article | Year |
|---|---|
The curious case of clioquinol.
Topics: Alzheimer Disease; Anti-Infective Agents, Local; Blindness; Clioquinol; Humans; Japan; Memory; Memor | 2009 |
[Analysis of SMON at 30 years after its outbreak ending: special reference to those patients with blindness].
Topics: Adult; Aged; Blindness; Clioquinol; Disease Outbreaks; Female; Follow-Up Studies; Humans; Japan; Mal | 2002 |
Clinical analysis of longstanding subacute myelo-optico-neuropathy: sequelae of clioquinol at 32 years after its ban.
Topics: Aged; Aged, 80 and over; Amebicides; Autonomic Nervous System Diseases; Blindness; Clioquinol; Cohor | 2004 |
American Academy of Pediatrics Committee on Drugs: Clioquinol (iodochlorhydroxyquin, vioform) and iodoquinol (diiodohydroxyquin): blindness and neuropathy.
Topics: Blindness; Child, Preschool; Clioquinol; Diaper Rash; Humans; Infant; Infant, Newborn; Iodoquinol; N | 1990 |
A case of optic atrophy possibly induced by quinoline in acrodermatitis enteropathica.
Topics: Acrodermatitis; Alopecia; Blindness; Body Height; Body Weight; Child, Preschool; Clioquinol; Diarrhe | 1974 |