clioquinol has been researched along with Allodynia in 1 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We also demonstrate that CQ-evoked mechanical hyperalgesia and cold allodynia require TRPA1 in vivo." | 1.35 | Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+. ( Andersson, DA; Bevan, S; Gentry, C; Moss, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersson, DA | 1 |
| Gentry, C | 1 |
| Moss, S | 1 |
| Bevan, S | 1 |
1 other study available for clioquinol and Allodynia
| Article | Year |
|---|---|
Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.
Topics: Animals; Antifungal Agents; Antiparasitic Agents; Cells, Cultured; Chelating Agents; Clioquinol; Gan | 2009 |