Page last updated: 2024-10-25

clioquinol and Allodynia

clioquinol has been researched along with Allodynia in 1 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Research Excerpts

ExcerptRelevanceReference
"We also demonstrate that CQ-evoked mechanical hyperalgesia and cold allodynia require TRPA1 in vivo."1.35Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+. ( Andersson, DA; Bevan, S; Gentry, C; Moss, S, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersson, DA1
Gentry, C1
Moss, S1
Bevan, S1

Other Studies

1 other study available for clioquinol and Allodynia

ArticleYear
Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, May-19, Volume: 106, Issue:20

    Topics: Animals; Antifungal Agents; Antiparasitic Agents; Cells, Cultured; Chelating Agents; Clioquinol; Gan

2009