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clioquinol and Allergic Encephalomyelitis

clioquinol has been researched along with Allergic Encephalomyelitis in 1 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Research Excerpts

ExcerptRelevanceReference
"The present study aimed to evaluate the therapeutic potential of clioquinol (CQ), a metal chelator, on multiple sclerosis pathogenesis."7.79Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model. ( Choi, BY; Chung, TN; Jang, BG; Kim, JH; Seo, JN; Sohn, M; Suh, SW; Wu, G, 2013)
"The present study aimed to evaluate the therapeutic potential of clioquinol (CQ), a metal chelator, on multiple sclerosis pathogenesis."3.79Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model. ( Choi, BY; Chung, TN; Jang, BG; Kim, JH; Seo, JN; Sohn, M; Suh, SW; Wu, G, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, BY1
Jang, BG1
Kim, JH1
Seo, JN1
Wu, G1
Sohn, M1
Chung, TN1
Suh, SW1

Other Studies

1 other study available for clioquinol and Allergic Encephalomyelitis

ArticleYear
Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model.
    Neurobiology of disease, 2013, Volume: 54

    Topics: Animals; Axons; Behavior, Animal; Blotting, Western; Chelating Agents; Clioquinol; Copper; Disease M

2013