clioquinol has been researched along with Allergic Encephalomyelitis in 1 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study aimed to evaluate the therapeutic potential of clioquinol (CQ), a metal chelator, on multiple sclerosis pathogenesis." | 7.79 | Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model. ( Choi, BY; Chung, TN; Jang, BG; Kim, JH; Seo, JN; Sohn, M; Suh, SW; Wu, G, 2013) |
| "The present study aimed to evaluate the therapeutic potential of clioquinol (CQ), a metal chelator, on multiple sclerosis pathogenesis." | 3.79 | Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model. ( Choi, BY; Chung, TN; Jang, BG; Kim, JH; Seo, JN; Sohn, M; Suh, SW; Wu, G, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, BY | 1 |
| Jang, BG | 1 |
| Kim, JH | 1 |
| Seo, JN | 1 |
| Wu, G | 1 |
| Sohn, M | 1 |
| Chung, TN | 1 |
| Suh, SW | 1 |
1 other study available for clioquinol and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model.
Topics: Animals; Axons; Behavior, Animal; Blotting, Western; Chelating Agents; Clioquinol; Copper; Disease M | 2013 |