clioquinol has been researched along with Allergic Encephalomyelitis in 1 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Excerpt | Relevance | Reference |
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"The present study aimed to evaluate the therapeutic potential of clioquinol (CQ), a metal chelator, on multiple sclerosis pathogenesis." | 7.79 | Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model. ( Choi, BY; Chung, TN; Jang, BG; Kim, JH; Seo, JN; Sohn, M; Suh, SW; Wu, G, 2013) |
"The present study aimed to evaluate the therapeutic potential of clioquinol (CQ), a metal chelator, on multiple sclerosis pathogenesis." | 3.79 | Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model. ( Choi, BY; Chung, TN; Jang, BG; Kim, JH; Seo, JN; Sohn, M; Suh, SW; Wu, G, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Choi, BY | 1 |
Jang, BG | 1 |
Kim, JH | 1 |
Seo, JN | 1 |
Wu, G | 1 |
Sohn, M | 1 |
Chung, TN | 1 |
Suh, SW | 1 |
1 other study available for clioquinol and Allergic Encephalomyelitis
Article | Year |
---|---|
Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model.
Topics: Animals; Axons; Behavior, Animal; Blotting, Western; Chelating Agents; Clioquinol; Copper; Disease M | 2013 |