clioquinol has been researched along with Ache in 33 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fourthly, there was no dose-response relationship." | 2.35 | Subacute myelo-optic neuropathy and clioquinol. An epidemiological case-history for diagnosis. ( Meade, TW, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansson, O | 1 |
| Herxheimer, A | 1 |
| Massons Cirera, J | 1 |
| Zunzunegui Costas, J | 1 |
| Titus Alvareda, F | 1 |
| Mamoli, B | 1 |
| Thaler, A | 2 |
| Heilig, P | 2 |
| Siakos, G | 1 |
| de Pinto, O | 1 |
| Burley, D | 1 |
| Meade, TW | 1 |
| Shimada, Y | 1 |
| Tsuji, T | 1 |
| Igata, A | 1 |
| Steinitz, H | 1 |
| Osterman, PO | 1 |
| Selby, G | 2 |
| Spillane, JD | 1 |
| Tateishi, J | 2 |
| Kuroda, S | 1 |
| Saito, A | 1 |
| Otsuki, S | 1 |
| Zeiller, P | 1 |
| Sensch, KH | 1 |
| Dahme, E | 1 |
| Nakae, K | 1 |
| Yamamoto, S | 1 |
| Shigematsu, I | 1 |
| Kono, R | 1 |
| Loewenstein, MS | 1 |
| Balows, A | 1 |
| Gangarosa, EJ | 1 |
| Aoyama, H | 1 |
| Oira, M | 1 |
| Ota, T | 1 |
| Yoshioka, S | 1 |
| Yoshida, T | 1 |
| Tagliavini, R | 1 |
| Lucchelli, PE | 1 |
| Colombi, A | 1 |
| Kean, BH | 1 |
| Roe, WP | 1 |
| Nelson, E | 1 |
| Pannekoek, JH | 1 |
| Bron, HL | 1 |
| Korten, JJ | 1 |
| Pinckers, AJ | 1 |
| Majoor, CL | 1 |
| van Beeck, JA | 1 |
| Scholten, JB | 1 |
| Jones, EL | 1 |
| Searle, CE | 1 |
| Smith, WT | 1 |
| Dimov, D | 1 |
| Grenier, B | 1 |
| Rolland, JC | 1 |
| Kiffer, A | 1 |
| Maupas, P | 1 |
| Oakley, GP | 1 |
| Wadia, NH | 1 |
| Papuziński, M | 1 |
| Wilmowska-Pietruszyńska, A | 1 |
| Gendre, JP | 1 |
| Barbanel, C | 1 |
| Degos, JD | 1 |
| Le Quintrec, Y | 1 |
| Inoue, N | 1 |
| Kuroiwa, Y | 1 |
| Ikeda, M | 1 |
| Yasukouchi, T | 1 |
1 review available for clioquinol and Ache
| Article | Year |
|---|---|
Subacute myelo-optic neuropathy and clioquinol. An epidemiological case-history for diagnosis.
Topics: Abdomen; Clioquinol; Environmental Pollution; Epidemiologic Methods; Female; Humans; Japan; Male; My | 1975 |
32 other studies available for clioquinol and Ache
| Article | Year |
|---|---|
Neurotoxicity of oxyquinolines.
Topics: Abdomen; Clioquinol; Humans; Myelitis; Optic Neuritis; Pain; Syndrome | 1980 |
[A case of myelo-optic neuropathy preceded by abdominal symptoms].
Topics: Abdomen; Clioquinol; Humans; Hydroxyquinolines; Male; Middle Aged; Optic Atrophy; Pain; Spinal Cord | 1983 |
[Subacute myelo-optic-neuropathy (S.M.O.N.) following treatment with clioquinol (author's transl)].
Topics: Abdomen, Acute; Aged; Clioquinol; Colostomy; Electromyography; Extremities; Female; Humans; Male; My | 1975 |
Clioquinol: time to act.
Topics: Abdomen; Clioquinol; Diarrhea; Humans; Myelitis; Optic Neuritis; Pain | 1977 |
Halogenated oxyquinoline derivatives and neurological syndromes.
Topics: Abdomen; Administration, Oral; Adult; Aged; Clioquinol; Feces; Female; Fluorescent Antibody Techniqu | 1971 |
Myelopathy after clioquinol treatment.
Topics: Abdomen; Adult; Clioquinol; Humans; Male; Myelitis; Nervous System Diseases; Neurologic Manifestatio | 1971 |
Subacute myelo-optic neuropathy in Australia.
Topics: Abdomen; Aged; Australia; Clioquinol; Diarrhea; Female; Humans; Male; Middle Aged; Myelitis; Neurolo | 1972 |
S.M.O.N.
Topics: Abdomen; Adult; Clioquinol; Diarrhea; Female; Humans; Myelitis; Optic Neuritis; Pain; Paresthesia | 1972 |
Neurotoxicity of clioquinol in laboratory animals.
Topics: Abdomen; Administration, Oral; Animals; Cats; Clioquinol; Dogs; Myelitis; Optic Neuritis; Pain | 1972 |
S.M.O.N.: different effects of dichloroquine and iodochloroquine in cats and mice.
Topics: Abdomen; Animals; Cats; Chlorine; Clioquinol; Mice; Myelitis; Optic Neuritis; Pain; Quinolines | 1973 |
Relation between subacute myelo-optic neuropathy (S.M.O.N.) and clioquinol: nationwide survey.
Topics: Abdomen; Adolescent; Adult; Aged; Child; Clioquinol; Dose-Response Relationship, Drug; Female; Human | 1973 |
Turista at an international congress in Mexico.
Topics: Abdomen; Adult; Climate; Clioquinol; Congresses as Topic; Diarrhea; Female; Food Supply; Gastroenter | 1973 |
[Epidemiological studies on subacute myelo-optico neuropathy (SMON) in the town of Yubara, Japan. 3].
Topics: Abdomen; Clioquinol; Female; Humans; Male; Myelitis; Optic Neuritis; Pain | 1970 |
[Analgesic effect of a corticosteroid for local use].
Topics: Antipyrine; Burns; Clioquinol; Ear Diseases; Female; Flumethasone; Fluorine; Glucocorticoids; Glycol | 1971 |
Subacute myelo-optic neuropathy: a probable case in the United States.
Topics: Adult; Clioquinol; Diarrhea; Gait; Giardiasis; Humans; Intestinal Diseases, Parasitic; Male; Neuromu | 1972 |
Going abroad.
Topics: Abdomen; Clioquinol; Diarrhea; Humans; Myelitis; Optic Neuritis; Pain | 1972 |
Subacute myelo-optico-neuropathy (SMON).
Topics: Abdomen; Clioquinol; Humans; Japan; Myelitis; Neurologic Manifestations; Optic Neuritis; Pain | 1972 |
[Neurotoxic symptoms following clioquinol (Enterovioform)].
Topics: Abdomen; Animals; Clioquinol; Humans; Intestinal Diseases; Myelitis; Optic Neuritis; Pain | 1972 |
[Subacute myelo-optico-neuropathy following use of large amounts of iodochlorhydroxyquinoline (Enterovioform)].
Topics: Abdomen; Adult; Aged; Clioquinol; Diarrhea; Female; Humans; Myelitis; Optic Neuritis; Pain | 1972 |
[Polyneuropathy following long-term use of clioquinol (Enterovioform)].
Topics: Abdomen; Aged; Clioquinol; Diarrhea; Humans; Male; Myelitis; Optic Neuritis; Pain | 1972 |
Peripheral neuropathy in rats fed with clioquinol.
Topics: Abdomen; Animals; Anti-Infective Agents, Local; Clioquinol; Humans; Myelitis; Optic Neuritis; Pain; | 1972 |
[Subacute myelo-optic neuropathy--toxic reaction or viral disease?].
Topics: Abdomen; Aged; Child; Clioquinol; Female; Humans; Myelitis; Optic Neuritis; Pain; Virus Diseases | 1972 |
[Subacute myeloradiculoneuritis and chloroiodoxyquinolein: poisoning or virus disease?].
Topics: Abdomen; Acute Disease; Aged; Child; Clioquinol; Diarrhea, Infantile; Drug Combinations; Enterovirus | 1973 |
Subacute myelo-optico-neuropathy (SMON)--neurotoxicity of clioquinols.
Topics: Abdomen; Aged; Clioquinol; Diarrhea; Enteritis; Female; Humans; Intestinal Absorption; Male; Middle | 1973 |
The neurotoxicity of the halogenated hydroxyquinolines. A commentary.
Topics: Abdomen; Anti-Infective Agents; Central Nervous System; Chlorquinaldol; Clioquinol; Disease Outbreak | 1973 |
Is there SMON in India?
Topics: Abdomen; Adult; Clioquinol; Female; Humans; India; Male; Middle Aged; Myelitis; Optic Neuritis; Pain | 1973 |
Comparative study of neurotoxicity of clioquinol, ethambutol, isoniazid and chloramphenicol in dogs.
Topics: Abdomen; Administration, Oral; Animals; Axons; Chloramphenicol; Clioquinol; Dogs; Ethambutol; Isonia | 1974 |
Warning on diiodohydroxyquin.
Topics: Abdomen; Acrodermatitis; Adult; Age Factors; Amebiasis; Child, Preschool; Chronic Disease; Clioquino | 1974 |
[Subacute myelo-optico neuropathy (author's transl)].
Topics: Abdomen; Aged; Clioquinol; Color Perception; Colostomy; Dose-Response Relationship, Drug; Humans; My | 1974 |
[Neurological complications in the course of treatment of acrodermatitis enteropathica with oxyquinoline derivatives].
Topics: Abdomen; Acrodermatitis; Child; Child, Preschool; Clioquinol; Female; Humans; Infant; Myelitis; Opti | 1974 |
[Serious sensory-motor neuropathy. A case of renal failure following clioquinol absorption].
Topics: Abdomen; Autopsy; Clioquinol; Demyelinating Diseases; Drug Tolerance; Electromyography; Humans; Kidn | 1974 |
[Analysis of the effects of chinoform on subacute myelo-optico-neuropathy (SMON)--application of linear regression analysis by logistic transformation].
Topics: Abdomen; Adolescent; Clioquinol; Dose-Response Relationship, Drug; Humans; Myelitis; Optic Neuritis; | 1974 |