clinoptilolite and Neuroendocrine-Tumors

Patients with neuroendocrine tumors (NETs) of the gastrointestinal tract suffer frequently from chronic diarrhea. A well characterized medical advice containing zeolite (Detoxsan. To overcome the therapy-refractory diarrhea of patients with NETs by the zeolite containing medical advice Detoxsan. A total of 20 patients (12 female and 8 male) suffering from diarrhea either by its frequency or from watery stool caused by NETs were included. In each patient, the diagnosis had been confirmed by histology and somatostatin receptors expression proven by positron emission tomography/computed tomography using Ga-68-labeled somatostatin analogs. All patients received standard-of-care pharmacotherapy and were additionally given Detoxsan. All patients enrolled in this pilot study did not only suffer from NETs, but also from comorbidities and treatment-resistant diarrhea. There was insufficient control of diarrhea, most probably due to the secretion of hormones like serotonin produced by the slowly growing and highly differentiated NETs. All patients only took Detoxsan. Detoxsan

Topics: Adsorption; Adult; Aged; Aged, 80 and over; Aluminum Silicates; Carcinoid Tumor; Comorbidity; Diarrhea; Female; Gallium Radioisotopes; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Neuroendocrine Tumors; Pilot Projects; Powders; Somatostatin; Treatment Outcome; Zeolites