clinoptilolite and Abdominal-Pain

Irritable bowel syndrome (IBS) is a highly prevalent gastrointestinal disorder with poor response to treatment. IBS with predominant diarrhea (IBS-D) is accompanied by abdominal pain as well as high stool frequency and urgency. Purified clinoptilolite-tuff (PCT), which is approved by the Food and Drug Administration for use as a dietary supplement with the brand name G-PUR. To assess whether symptoms of IBS-D can be ameliorated by oral treatment with PCT.. In this randomized, placebo-controlled, double-blind pilot study, 30 patients with IBS-D diagnosis based on Rome IV criteria were enrolled. Following a 4-wk run-in phase, 14 patients were randomized to receive a 12-wk treatment with G-PUR. The proportions of SGA of Relief responders after 12 wk were comparable in both groups, namely 21% in the G-PUR. In this randomized, double-blind, placebo-controlled study, the PCT product, G-PUR

Topics: Abdominal Pain; Diarrhea; Double-Blind Method; Humans; Irritable Bowel Syndrome; Pilot Projects; Treatment Outcome