clenbuterol has been researched along with Obstructive Lung Diseases in 27 studies
Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a single-blind placebo-controlled trial in 12 patients with advanced chronic obstructive pulmonary disease (COPD) we compared the effects of nebulized salbutamol (1 mg), clenbuterol (30 micrograms) and placebo (4 ml of normal saline) on spirometric indices (FVC, FEV1), maximal expiratory flows (Vmax50 and Vmax25), the distance walked in 6 min (6MD), assessment of breathlessness by visual analogue scale (VAS), and estimates by the patients of perceived exertion (RPE)." | 5.06 | Effects of beta-agonists on breathlessness and exercise tolerance in patients with chronic obstructive pulmonary disease. ( Galavotti, V; Papiris, S; Sturani, C, 1986) |
| "The acute bronchodilator effect of the beta 2-adrenoceptor agonist terbutaline was tested single-blind cross-over in out-patients with chronic obstructive airways disease (intrinsic asthma)." | 5.04 | [Lung function studies with the bronchodilator terbutaline]. ( Bonelli, J; Hitzenberger, G; Kaik, G; Laggner, A; Magometschnigg, D, 1979) |
| " with clenbuterol (as Ventipulmin Syrup), beginning with the lowest dosage of 0." | 2.67 | Clinical efficacy and safety of clenbuterol HCl when administered to effect in horses with chronic obstructive pulmonary disease (COPD). ( Aviad, AD; Erichsen, DF; Kennedy, TJ; Schultz, RH, 1994) |
| "Mabuterol was found to have a good, clinically useful, bronchodilating effect and to possess excellent tolerability at doses of 40-60 micrograms." | 2.65 | Pilot clinical trial with a new beta 2-sympathomimetic bronchodilator, mabuterol. ( Baines, A; Scholz, HJ; Ulmer, WT, 1984) |
| "Ambroxol was effective in only 1 of 5 tested lung areas and did not prove to enhance whole lung clearance significantly." | 2.65 | Effects of a beta adrenergic drug and a secretolytic agent on regional mucociliary clearance in patients with COLD. ( Dorow, P; Felix, R; Weiss, T, 1981) |
| "Clenbuterol is a beta-2-sympathicomimetic, from a series of substituted phenylethanolamines, and it is characterised by good absorption and prolonged action after systemic administration." | 2.65 | Dose response relationship of clenbuterol (NAB 365) as a solution for inhalation. ( Herzog, H; Perruchoud, A; Tschan, M, 1979) |
| "Oral clenbuterol was effective in only seven of 15 cases." | 1.29 | Obstructive pulmonary disease in 18 horses at summer pasture. ( Mair, TS, 1996) |
| " The characteristics of the oral route are easy usage, precise dosage and assured effects." | 1.27 | Oral beta 2-selective adrenergic bronchodilators. ( Daniotti, S; Dottorini, M; Grassi, V; Schiassi, M; Tantucci, C, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (59.26) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laan, TT | 2 |
| Bull, S | 2 |
| Pirie, RS | 1 |
| Fink-Gremmels, J | 2 |
| van Nieuwstadt, RA | 1 |
| van den Hoven, R | 1 |
| Duvigneau, JC | 1 |
| Hartl, RT | 1 |
| Gemeiner, M | 1 |
| Ulmer, WT | 1 |
| Scholz, HJ | 1 |
| Baines, A | 1 |
| Jaffé, G | 1 |
| Grimshaw, JJ | 1 |
| Breuer, D | 1 |
| Becker, M | 1 |
| Baronti, A | 1 |
| Grieco, A | 1 |
| Vibelli, C | 1 |
| Weiss, T | 1 |
| Dorow, P | 1 |
| Felix, R | 1 |
| Nolte, D | 1 |
| Derksen, FJ | 1 |
| Erichsen, DF | 1 |
| Aviad, AD | 1 |
| Schultz, RH | 1 |
| Kennedy, TJ | 1 |
| Mair, TS | 1 |
| Törneke, K | 1 |
| Ingvast Larsson, C | 1 |
| Appelgren, LE | 1 |
| Harkins, JD | 1 |
| Robinson, NE | 1 |
| Woods, WE | 1 |
| Lehner, AF | 1 |
| Smith, MD | 1 |
| Gates, RS | 1 |
| Fisher, M | 1 |
| Tobin, T | 1 |
| Rensch, H | 1 |
| Renovanz, HD | 1 |
| Flohr, E | 1 |
| Bischoff, KO | 1 |
| Montero Benzo, R | 1 |
| Salas Font, A | 1 |
| Tschan, M | 1 |
| Perruchoud, A | 1 |
| Herzog, H | 1 |
| Kaik, G | 1 |
| Bonelli, J | 1 |
| Hitzenberger, G | 1 |
| Laggner, A | 1 |
| Magometschnigg, D | 1 |
| Traub-Dargatz, JL | 1 |
| McKinnon, AO | 1 |
| Thrall, MA | 1 |
| Jones, RL | 1 |
| Bruyninckx, W | 1 |
| Blancquaert, AM | 1 |
| Dargatz, DA | 1 |
| Fiaccadori, E | 1 |
| Coffrini, E | 1 |
| Ronda, N | 1 |
| Vezzani, A | 1 |
| Cacciani, G | 1 |
| Fracchia, C | 1 |
| Rampulla, C | 1 |
| Borghetti, A | 1 |
| Hackett, IJ | 1 |
| Turgut, K | 1 |
| Sasse, HH | 1 |
| Grassi, V | 1 |
| Daniotti, S | 1 |
| Schiassi, M | 2 |
| Dottorini, M | 1 |
| Tantucci, C | 1 |
| Capretti, A | 1 |
| Dantes, M | 1 |
| De Gasperi, R | 1 |
| D'Ambrosio, V | 1 |
| Bertoli, L | 1 |
| Graziina, A | 1 |
| Lo Cicero, S | 1 |
| Motelli, R | 1 |
| Papiris, S | 1 |
| Galavotti, V | 1 |
| Sturani, C | 1 |
1 review available for clenbuterol and Obstructive Lung Diseases
| Article | Year |
|---|---|
[Clenbuterol: review of a new broncholytic agent].
Topics: Bronchi; Chronic Disease; Clenbuterol; Ethanolamines; Humans; Lung Diseases, Obstructive | 1977 |
11 trials available for clenbuterol and Obstructive Lung Diseases
| Article | Year |
|---|---|
Clenbuterol affects the expression of messenger RNA for interleukin 10 in peripheral leukocytes from horses challenged intrabronchially with lipopolysaccharides.
Topics: Animals; Bronchodilator Agents; Clenbuterol; Gene Expression Regulation; Horse Diseases; Horses; Int | 2006 |
Pilot clinical trial with a new beta 2-sympathomimetic bronchodilator, mabuterol.
Topics: Adrenergic beta-Agonists; Adult; Aged; Airway Resistance; Blood Pressure; Bronchodilator Agents; Cle | 1984 |
Clenbuterol and salbutamol in the symptomatic treatment of patients with reversible airways obstruction.
Topics: Adolescent; Adult; Aged; Albuterol; Clenbuterol; Clinical Trials as Topic; Drug Administration Sched | 1983 |
Oral NAB 365 (clenbuterol) and terbutaline in chronic obstructive lung disease: a double-blind, two-week study.
Topics: Aged; Blood Gas Analysis; Bronchodilator Agents; Clenbuterol; Clinical Trials as Topic; Double-Blind | 1980 |
Effects of a beta adrenergic drug and a secretolytic agent on regional mucociliary clearance in patients with COLD.
Topics: Albumins; Ambroxol; Bromhexine; Cilia; Clenbuterol; Clinical Trials as Topic; Double-Blind Method; E | 1981 |
Clinical efficacy and safety of clenbuterol HCl when administered to effect in horses with chronic obstructive pulmonary disease (COPD).
Topics: Animals; Bronchodilator Agents; Clenbuterol; Dose-Response Relationship, Drug; Female; Horse Disease | 1994 |
[Comparative studies on the oral therapy of obstructive respiratory tract diseases with clenbuterol, fenoterol and depot-orciprenaline (double-blind study)].
Topics: Administration, Oral; Bronchodilator Agents; Clenbuterol; Clinical Trials as Topic; Delayed-Action P | 1978 |
[A study of the alveolar-arterial oxygen gradients and intrapulmonary shunt under the action of NAB-365, a new exogenous catecholamine of selective beta-2 action (author's transl)].
Topics: Clenbuterol; Clinical Trials as Topic; Drug Evaluation; Ethanolamines; Female; Humans; Lung; Lung Di | 1979 |
Dose response relationship of clenbuterol (NAB 365) as a solution for inhalation.
Topics: Adult; Aerosols; Airway Resistance; Bronchitis; Clenbuterol; Clinical Trials as Topic; Dose-Response | 1979 |
[Lung function studies with the bronchodilator terbutaline].
Topics: Adult; Aged; Airway Resistance; Asthma; Atropine; Clenbuterol; Drug Combinations; Ethylenediamines; | 1979 |
Effects of beta-agonists on breathlessness and exercise tolerance in patients with chronic obstructive pulmonary disease.
Topics: Aged; Albuterol; Clenbuterol; Clinical Trials as Topic; Dyspnea; Ethanolamines; Forced Expiratory Vo | 1986 |
15 other studies available for clenbuterol and Obstructive Lung Diseases
| Article | Year |
|---|---|
The anti-inflammatory effects of IV administered clenbuterol in horses with recurrent airway obstruction.
Topics: Animals; Antigens, Fungal; Aspergillus fumigatus; Bronchoalveolar Lavage Fluid; Bronchodilator Agent | 2006 |
The effect of aerosolized and intravenously administered clenbuterol and aerosolized fluticasone propionate on horses challenged with Aspergillus fumigatus antigen.
Topics: Administration, Inhalation; Androstadienes; Animals; Antigens, Fungal; Aspergillus fumigatus; Bronch | 2006 |
[Acetylcysteine (Fluimucil) in the treatment of COPD of the horse].
Topics: Acetylcysteine; Administration, Oral; Animals; Clenbuterol; Drug Therapy, Combination; Female; Horse | 1983 |
[New developments in the field of bronchospasmolytics].
Topics: Albuterol; Aminophylline; Bronchial Spasm; Bronchodilator Agents; Clenbuterol; Fenoterol; Glucocorti | 1980 |
Anecdotes and clinical trials: the story of clenbuterol.
Topics: Anecdotes as Topic; Animals; Bronchodilator Agents; Clenbuterol; Clinical Trials as Topic; Horse Dis | 1994 |
Obstructive pulmonary disease in 18 horses at summer pasture.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Bronchodilato | 1996 |
A comparison between clenbuterol, salbutamol and terbutaline in relation to receptor binding and in vitro relaxation of equine tracheal muscle.
Topics: Albuterol; Animals; Binding, Competitive; Bronchodilator Agents; Clenbuterol; Dose-Response Relation | 1998 |
Intratracheal clenbuterol in the horse: its pharmacological efficacy and analytical detection.
Topics: Administration, Inhalation; Animals; Bronchodilator Agents; Clenbuterol; Enzyme-Linked Immunosorbent | 2000 |
Evaluation of clinical signs of disease, bronchoalveolar and tracheal wash analysis, and arterial blood gas tensions in 13 horses with chronic obstructive pulmonary disease treated with prednisone, methyl sulfonmethane, and clenbuterol hydrochloride.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Carbon Dioxide; Clen | 1992 |
Hypophosphatemia in course of chronic obstructive pulmonary disease. Prevalence, mechanisms, and relationships with skeletal muscle phosphorus content.
Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Clenbuterol; Female; Furosemide; Humans; Kidney; Lun | 1990 |
Oil seed rape and equine respiratory disease.
Topics: Animals; Brassica; Clenbuterol; Horse Diseases; Horses; Lung Diseases, Obstructive | 1990 |
Influence of clenbuterol on mucociliary transport in healthy horses and horses with chronic obstructive pulmonary disease.
Topics: Animals; Clenbuterol; Ethanolamines; Female; Horse Diseases; Horses; Lung Diseases, Obstructive; Mal | 1989 |
Oral beta 2-selective adrenergic bronchodilators.
Topics: Administration, Oral; Adrenergic beta-Agonists; Aged; Asthma; Bronchodilator Agents; Child; Clenbute | 1986 |
[Changes in blood potassium induced by the abuse of 3 beta 2-agonist drugs].
Topics: Administration, Inhalation; Aged; Albuterol; Clenbuterol; Ethanolamines; Female; Fenoterol; Humans; | 1987 |
Effects of clenbuterol on pulmonary circulation and on oxygen delivery in chronic airflow obstruction.
Topics: Aged; Clenbuterol; Ethanolamines; Hemodynamics; Humans; Lung Diseases, Obstructive; Male; Middle Age | 1986 |