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clenbuterol and Muscle Relaxation

clenbuterol has been researched along with Muscle Relaxation in 21 studies

Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" Spontaneous detrusor muscle contractions were unaffected by glibenclamide (K(ATP) channel blocker) but were reduced when pinacidil (K(ATP) channel opener) concentrations exceeded 10(-5) M."3.70K(ATP) channels mediate the beta(2)-adrenoceptor agonist-induced relaxation of rat detrusor muscle. ( Elliott, RA; Hudman, D; Norman, RI, 2000)
"We examined the effects of four beta 2-agonists, clenbuterol, metaproterenol, procaterol, and albuterol, on the contractility of fatigued canine diaphragm."3.68Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo. ( Miyashita, A; Numata, H; Okubo, T; Suzuki, M; Suzuki, S, 1993)
"(+)-Clenbuterol was at least 1,000 times less potent in this respect."1.27Steric aspects of agonism and antagonism at beta-adrenoceptors: experiments with the enantiomers of clenbuterol. ( Waldeck, B; Widmark, E, 1985)
"Clenbuterol was a potent partial beta adrenoceptor agonist in both tissues based on the following observations: 1."1.26Analysis of the beta 1 and beta 2 adrenoceptor interactions of the partial agonist, clenbuterol (NAB365), in the rat jugular vein and atria. ( Bemis, KG; Cohen, ML; Wiley, KS, 1982)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's8 (38.10)18.2507
2000's7 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uchida, H1
Shishido, K1
Nomiya, M1
Yamaguchi, O1
Yamanishi, T1
Yasuda, K1
Kitahara, S1
Nakai, H1
Yoshida, K1
Iizuka, H1
Badawi, JK1
Seja, T1
Uecelehan, H1
Honeck, P1
Kwon, ST1
Bross, S1
Langbein, S1
van der Heijden, PJ1
van Amsterdam, JG1
Zaagsma, J1
Osada, E1
Sakaya, S1
Sanai, K1
Seri, K1
Cohen, ML1
Wiley, KS1
Bemis, KG1
Schilt, R1
Hooijerink, H1
Huf, FA1
Zuiderveld, OP1
Bast, A1
Numata, H1
Suzuki, S1
Miyashita, A1
Suzuki, M1
Okubo, T1
Bramuglia, GF3
Kazanietz, MG2
Pezman, E1
Enero, MA2
Lezama, EJ1
Konkar, AA1
Salazar-Bookaman, MM1
Miller, DD1
Feller, DR1
Törneke, K1
Ingvast Larsson, C1
Appelgren, LE1
Petrou, M1
Clarke, S1
Morrison, K1
Bowles, C1
Dunn, M1
Yacoub, M1
Rubio, MC2
Hudman, D1
Elliott, RA1
Norman, RI1
Horinouchi, T1
Koike, K1
Ingvast-Larsson, C1
Lagente, V1
Lefort, J1
Vargaftig, BB1
Waldeck, B1
Widmark, E1
Streller, I1

Other Studies

21 other studies available for clenbuterol and Muscle Relaxation

ArticleYear
Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via beta-adrenoceptors.
    European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Animals; Benzocycloheptenes; Clenbut

2005
Effects of 138-355, a beta3-adrenoceptor selective agonist, on relaxation of the human detrusor muscle in vitro.
    Neurourology and urodynamics, 2006, Volume: 25, Issue:7

    Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albutero

2006
Relaxation of human detrusor muscle by selective beta-2 and beta-3 agonists and endogenous catecholamines.
    Urology, 2007, Volume: 69, Issue:4

    Topics: Adrenergic beta-Agonists; Aged; Catecholamines; Clenbuterol; Dose-Response Relationship, Drug; Ethan

2007
Desensitization of smooth muscle and mast cell beta-adrenoceptors in the airways of the guinea pig.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Clenbuterol; Dose-Response Relationship, Drug; Fenote

1984
Pharmacological studies of mabuterol, a new selective beta 2-stimulant. III: Effects on the central nervous system, striated muscle and carbohydrate and lipid metabolism.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:11A

    Topics: Adrenergic beta-Agonists; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Carbohydrate Metab

1984
Analysis of the beta 1 and beta 2 adrenoceptor interactions of the partial agonist, clenbuterol (NAB365), in the rat jugular vein and atria.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 320, Issue:2

    Topics: Animals; Clenbuterol; Ethanolamines; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Jugular

1982
Screening of cattle urine samples for the presence of beta-agonists with a functional test: some preliminary results.
    The Analyst, 1994, Volume: 119, Issue:12

    Topics: Adrenergic beta-Agonists; Animals; Cattle; Chromatography, Ion Exchange; Clenbuterol; Guinea Pigs; I

1994
Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo.
    Respiration physiology, 1993, Volume: 94, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Pressure; Clenbuterol; Diaphragm; Dogs; Dose-Res

1993
Beta-adrenoceptor desensitization by/clenbuterol in rat uterus.
    General pharmacology, 1993, Volume: 24, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Estradiol; Female; In Vitr

1993
Pharmacological study of atypical beta-adrenoceptors in rat esophageal smooth muscle.
    European journal of pharmacology, 1996, Jul-11, Volume: 308, Issue:1

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta

1996
A comparison between clenbuterol, salbutamol and terbutaline in relation to receptor binding and in vitro relaxation of equine tracheal muscle.
    Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:5

    Topics: Albuterol; Animals; Binding, Competitive; Bronchodilator Agents; Clenbuterol; Dose-Response Relation

1998
Clenbuterol increases stroke power and contractile speed of skeletal muscle for cardiac assist.
    Circulation, 1999, Feb-09, Volume: 99, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Body Weight; Clenbuterol; Drug Evaluation, Preclinical; Electric

1999
Effects of clenbuterol treatment on the relaxant response in rat uterus.
    Pharmacological research, 2000, Volume: 41, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clenbuterol; Cyclic AMP; Dihydroalpr

2000
K(ATP) channels mediate the beta(2)-adrenoceptor agonist-induced relaxation of rat detrusor muscle.
    European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1

    Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Cycli

2000
Effects of optical isomers of clenbuterol on the relaxant response in rat uterus.
    Pharmacological research, 2001, Volume: 43, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Dose-Response Relationship, Drug; Female; Muscle Rel

2001
Functional properties of atypical beta-adrenoceptors on the guinea pig duodenum.
    European journal of pharmacology, 2001, Mar-23, Volume: 416, Issue:1-2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alprenolol; Animals; Bupranolol; C

2001
Decreased beta-adrenoceptor-mediated vasodilation in aorta from aged rats: possible involvement of a stimulatory GTP-binding protein.
    European journal of pharmacology, 1991, Jun-06, Volume: 198, Issue:2-3

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Aorta; Clenbuterol; Colforsin; Cycli

1991
Relaxant effects of theophylline and clenbuterol on tracheal smooth muscle from horse and rat in vitro.
    Journal of veterinary pharmacology and therapeutics, 1991, Volume: 14, Issue:3

    Topics: Animals; Carbachol; Clenbuterol; Horses; Male; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Inbred

1991
Pulmonary anti-anaphylactic activity of clenbuterol tested on actively and passively sensitized guinea-pigs.
    European journal of pharmacology, 1985, Dec-17, Volume: 119, Issue:3

    Topics: Acetylcholine; Anaphylaxis; Animals; Bronchi; Clenbuterol; Ethanolamines; Female; Guinea Pigs; Hista

1985
Steric aspects of agonism and antagonism at beta-adrenoceptors: experiments with the enantiomers of clenbuterol.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:3

    Topics: Animals; Carbachol; Clenbuterol; Ethanolamines; Guinea Pigs; Heart Ventricles; In Vitro Techniques;

1985
Uterine relaxation by clenbuterol and fenoterol in conscious rats.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A

    Topics: Administration, Oral; Animals; Clenbuterol; Dose-Response Relationship, Drug; Ethanolamines; Female;

1985