clenbuterol has been researched along with Motor Neuron Disease in 2 studies
Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with clenbuterol, a beta(2)-adrenoceptor agonist that can enhance regeneration of motor neuron axons, opposed the development of motor deficits in parallel with a reduced proportion of motor neurons with eccentric nuclei consistent with improved synaptic function." | 1.32 | Clenbuterol retards loss of motor function in motor neuron degeneration mice. ( Etlinger, JD; Peng, H; Zeman, RJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zeman, RJ | 1 |
| Peng, H | 1 |
| Etlinger, JD | 1 |
| Puls, I | 1 |
| Beck, M | 1 |
| Giess, R | 1 |
| Magnus, T | 1 |
| Ochs, G | 1 |
| Toyka, KV | 1 |
1 review available for clenbuterol and Motor Neuron Disease
| Article | Year |
|---|---|
[Clenbuterol in amyotrophic lateral sclerosis. No indication for a positive effect].
Topics: Adrenergic beta-Agonists; Clenbuterol; Humans; Motor Neuron Disease; Neurologic Examination; Treatme | 1999 |
1 other study available for clenbuterol and Motor Neuron Disease
| Article | Year |
|---|---|
Clenbuterol retards loss of motor function in motor neuron degeneration mice.
Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Diagnostic Techniques, Neurological; Disease Models, | 2004 |