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clenbuterol and Insulin Sensitivity

clenbuterol has been researched along with Insulin Sensitivity in 11 studies

Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.

Research Excerpts

ExcerptRelevanceReference
"The present study was conducted to determine the effect of chronic administration of the long-acting beta(2)-adrenergic agonist clenbuterol on rats that are genetically prone to insulin resistance and impaired glucose tolerance."7.71Effects of clenbuterol on insulin resistance in conscious obese Zucker rats. ( Ding, Z; Fogt, D; Hancock, J; Ivy, JL; Lee, M; Pan, SJ, 2001)
"This study compared the effects of aerobic exercise training and chronic administration of the selective beta 2-adrenergic agonist clenbuterol on whole body and skeletal muscle insulin resistance in obese (fa/fa) Zucker rats."7.68Exercise training and clenbuterol reduce insulin resistance of obese Zucker rats. ( Banks, EA; Brozinick, JT; Cortez, MY; Ivy, JL; Torgan, CE; Wilcox, RE, 1993)
"Clenbuterol was given as 2 intramuscular injections with an interval of about 12 h."5.30Clenbuterol-induced insulin resistance in calves measured by hyperinsulinemic, euglycemic clamp technique. ( Hänni, A; Jacobsson, SO; Luthman, J; Sternbauer, K, 1998)
"C57Bl/6N mice with diet-induced obesity were treated both acutely and for up to 42 days with a wide range of clenbuterol dosages and treatment durations."3.96Treatment with a β-2-adrenoceptor agonist stimulates glucose uptake in skeletal muscle and improves glucose homeostasis, insulin resistance and hepatic steatosis in mice with diet-induced obesity. ( Åslund, A; Bengtsson, T; Berlin, R; Dehvari, N; Forsberg, E; Halleskog, C; Hoeks, J; Kalinovich, A; Olsen, J; Östenson, CG; Rinde, M; Sandström, A; Schaart, G; van Beek, S; Zacharewicz, E, 2020)
"The present study was conducted to determine the effect of chronic administration of the long-acting beta(2)-adrenergic agonist clenbuterol on rats that are genetically prone to insulin resistance and impaired glucose tolerance."3.71Effects of clenbuterol on insulin resistance in conscious obese Zucker rats. ( Ding, Z; Fogt, D; Hancock, J; Ivy, JL; Lee, M; Pan, SJ, 2001)
"A possible mechanism by which chronic clenbuterol treatment causes multiple physiological changes in skeletal muscle that leads to reduced insulin resistance in the obese Zucker rat (falfa) was investigated."3.71Attenuation of insulin resistance by chronic beta2-adrenergic agonist treatment possible muscle specific contributions. ( Castle, A; Ivy, JL; Kuo, CH; Yaspelkis, BB, 2001)
"The effects of aerobic exercise training, chronic administration of the selective beta 2-adrenergic agonist clenbuterol, and the combination of these two treatments on muscle insulin resistance were compared in female obese (fa/fa) Zucker rats."3.68Interaction of aerobic exercise training and clenbuterol: effects on insulin-resistant muscle. ( Brozinick, JT; Etgen, GJ; Ivy, JL; Torgan, CE; Wilcox, RE, 1993)
"This study compared the effects of aerobic exercise training and chronic administration of the selective beta 2-adrenergic agonist clenbuterol on whole body and skeletal muscle insulin resistance in obese (fa/fa) Zucker rats."3.68Exercise training and clenbuterol reduce insulin resistance of obese Zucker rats. ( Banks, EA; Brozinick, JT; Cortez, MY; Ivy, JL; Torgan, CE; Wilcox, RE, 1993)
"Previous studies in fetuses with intrauterine growth restriction (IUGR) have shown that adrenergic dysregulation was associated with low insulin concentrations and greater insulin sensitivity."1.51Postnatal β2 adrenergic treatment improves insulin sensitivity in lambs with IUGR but not persistent defects in pancreatic islets or skeletal muscle. ( Allen, RE; Anderson, MJ; Antolic, AT; Camacho, LE; Davis, MA; Goyal, R; Hay, WW; Kelly, AC; Limesand, SW; Papas, KK; Steyn, LV; Yates, DT, 2019)
"Clenbuterol was given as 2 intramuscular injections with an interval of about 12 h."1.30Clenbuterol-induced insulin resistance in calves measured by hyperinsulinemic, euglycemic clamp technique. ( Hänni, A; Jacobsson, SO; Luthman, J; Sternbauer, K, 1998)
"Clenbuterol treatment did, however, increase citrate synthase activity and GLUT-4 protein in soleus."1.29Fiber type-specific effects of clenbuterol and exercise training on insulin-resistant muscle. ( Etgen, GJ; Ivy, JL; Kang, HY; Torgan, CE, 1995)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (45.45)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Meister, J2
Bone, DBJ2
Knudsen, JR2
Barella, LF2
Liu, L1
Lee, R1
Gavrilova, O2
Chen, M2
Weinstein, LS2
Kleinert, M2
Jensen, TE2
Wess, J2
Velenosi, TJ1
Akhmedov, D1
Lee, RJ1
Cohen, AH1
Cui, Y1
Karsenty, G1
Berdeaux, R1
Richter, EA1
Yates, DT1
Camacho, LE1
Kelly, AC1
Steyn, LV1
Davis, MA1
Antolic, AT1
Anderson, MJ1
Goyal, R1
Allen, RE1
Papas, KK1
Hay, WW1
Limesand, SW1
Kalinovich, A1
Dehvari, N1
Åslund, A1
van Beek, S1
Halleskog, C1
Olsen, J1
Forsberg, E1
Zacharewicz, E1
Schaart, G1
Rinde, M1
Sandström, A1
Berlin, R1
Östenson, CG1
Hoeks, J1
Bengtsson, T1
Torgan, CE3
Etgen, GJ2
Kang, HY1
Ivy, JL5
Kim, J1
Shigetomi, S1
Tanaka, K1
Yamada, ZO1
Hashimoto, S1
Fukuchi, S1
Brozinick, JT2
Wilcox, RE2
Banks, EA1
Cortez, MY1
Sternbauer, K1
Luthman, J1
Hänni, A1
Jacobsson, SO1
Pan, SJ1
Hancock, J1
Ding, Z1
Fogt, D1
Lee, M1
Castle, A1
Yaspelkis, BB1
Kuo, CH1

Other Studies

11 other studies available for clenbuterol and Insulin Sensitivity

ArticleYear
In vivo metabolic effects after acute activation of skeletal muscle G
    Molecular metabolism, 2022, Volume: 55

    Topics: Animals; Clenbuterol; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; GTP-Binding P

2022
Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells.
    Nature communications, 2022, 01-10, Volume: 13, Issue:1

    Topics: Animals; Biochemical Phenomena; Cellular Reprogramming; Clenbuterol; Female; Glucose; Homeostasis; H

2022
Postnatal β2 adrenergic treatment improves insulin sensitivity in lambs with IUGR but not persistent defects in pancreatic islets or skeletal muscle.
    The Journal of physiology, 2019, Volume: 597, Issue:24

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Atenolol; Cell

2019
Treatment with a β-2-adrenoceptor agonist stimulates glucose uptake in skeletal muscle and improves glucose homeostasis, insulin resistance and hepatic steatosis in mice with diet-induced obesity.
    Diabetologia, 2020, Volume: 63, Issue:8

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Clenbuterol; Fatty Liver; Glucose; Homeostasis; Insuli

2020
Fiber type-specific effects of clenbuterol and exercise training on insulin-resistant muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 79, Issue:1

    Topics: Animals; Citrate (si)-Synthase; Clenbuterol; Deoxyglucose; Female; Glucose Transporter Type 4; Insul

1995
[The role of beta 2-adrenoceptor on the pathogenesis of insulin resistance in essential hypertension].
    Nihon Naibunpi Gakkai zasshi, 1994, Jun-20, Volume: 70, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Aged; Blood Glucose; Blood Pressure; Clenbuterol; Humans; Hypertens

1994
Interaction of aerobic exercise training and clenbuterol: effects on insulin-resistant muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:4

    Topics: Aerobiosis; Animals; Body Weight; Citrate (si)-Synthase; Clenbuterol; Enzymes; Female; Glucose; Hind

1993
Exercise training and clenbuterol reduce insulin resistance of obese Zucker rats.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1

    Topics: 3-O-Methylglucose; Animals; Biological Transport; Body Weight; Citrate (si)-Synthase; Clenbuterol; D

1993
Clenbuterol-induced insulin resistance in calves measured by hyperinsulinemic, euglycemic clamp technique.
    Acta veterinaria Scandinavica, 1998, Volume: 39, Issue:2

    Topics: Animals; Blood Glucose; Bronchodilator Agents; Cattle; Cattle Diseases; Clenbuterol; Glucose; Glucos

1998
Effects of clenbuterol on insulin resistance in conscious obese Zucker rats.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Blood Glucose; Body Weight; Clenbuterol; Female; Glucose; Glycoge

2001
Attenuation of insulin resistance by chronic beta2-adrenergic agonist treatment possible muscle specific contributions.
    Life sciences, 2001, Jun-22, Volume: 69, Issue:5

    Topics: 3-O-Methylglucose; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Biologica

2001