Page last updated: 2024-10-25

clenbuterol and Hypertrophy

clenbuterol has been researched along with Hypertrophy in 42 studies

Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
"Clenbuterol, a β₂-adrenergic agonist, increases the hypertrophy of skeletal muscle."7.78IGF and myostatin pathways are respectively induced during the earlier and the later stages of skeletal muscle hypertrophy induced by clenbuterol, a β₂-adrenergic agonist. ( Abo, T; Hamada, Y; Iida, RH; Kaneko, S; Suga, T; Yamada, H; Yamane, A, 2012)
"Analyses were performed to evaluate the roles of the beta1- and beta2-adrenergic receptors in the skeletal muscle hypertrophy and anti-atrophy response to the beta-adrenergic agonist, clenbuterol."7.71Skeletal muscle hypertrophy and anti-atrophy effects of clenbuterol are mediated by the beta2-adrenergic receptor. ( Cody, DB; Hinkle, RT; Hodge, KMB; Isfort, RJ; Kobilka, BK; Sheldon, RJ, 2002)
" The beta 2-adrenoceptor agonist clenbuterol was used to investigate its potential to selectively induce skeletal muscle hypertrophy, particularly the latissimus dorsi muscle (LDM), independent of adverse effects on cardiac muscle."7.69Clenbuterol induces hypertrophy of the latissimus dorsi muscle and heart in the rat with molecular and phenotypic changes. ( Boheler, KR; Petrou, M; Wynne, DG; Yacoub, MH, 1995)
" When rats were fed with clenbuterol for 7 days skeletal muscle mass increased by 21% in the tonic soleus and phasic plantaris muscles and a 16% hypertrophy of the heart was also induced."7.68Effects of the cyclo-oxygenase inhibitor, fenbufen, on clenbuterol-induced hypertrophy of cardiac and skeletal muscle of rats. ( Bain, P; Delday, MI; Maltin, CA; McMillan, DN; Noble, BS; Palmer, RM, 1990)
"05%) diet in rats had no effect in inducing muscle hypertrophy and in changing contractile properties, although it had some similar effects of clenbuterol on muscle gene expression."4.12Effects of long-term treatment with dietary theobromine on rat skeletal muscles. ( Inaoka, PT; Madokoro, S; Ohno-Shosaku, T; Sugimoto, N; Tanaka, S; Yamazaki, T, 2022)
"Clenbuterol (CB), a selective β2-adrenergic receptor (AR) agonist, induces muscle hypertrophy and counteracts muscle atrophy."3.83Role of phosphodiesterase 4 expression in the Epac1 signaling-dependent skeletal muscle hypertrophic action of clenbuterol. ( Cai, W; Fujita, T; Ishikawa, Y; Ito, A; Jin, H; Kawamura, N; Mototani, Y; Nariyama, M; Ohnuki, Y; Okumura, S; Saeki, Y; Shiozawa, K; Suita, K; Umeki, D; Yagisawa, Y, 2016)
"Clenbuterol is a β2 -adrenergic receptor agonist known to induce skeletal muscle hypertrophy and a slow-to-fast phenotypic shift."3.81Chronic clenbuterol treatment compromises force production without directly altering skeletal muscle contractile machinery. ( Bonnieu, A; Candau, RB; Cazorla, O; Chopard, A; Douillard, A; Galbès, O; Lacampagne, A; Lionne, C; Philippe, AG; Py, G; Ramonatxo, C; Sanchez, AM; Sirvent, P, 2015)
" We reported that clenbuterol (CB) induced masseter muscle hypertrophy and slow-to-fast myosin heavy chain (MHC) isoform transition through direct muscle β2-adrenergic receptor stimulation."3.81Protective Effects of Clenbuterol against Dexamethasone-Induced Masseter Muscle Atrophy and Myosin Heavy Chain Transition. ( Fujita, T; Mototani, Y; Nakamura, Y; Ohnuki, Y; Okumura, S; Saeki, Y; Shiozawa, K; Suita, K; Umeki, D, 2015)
"Chronic administration of clenbuterol (CB), a lipophilic β₂-adrenoceptor (β₂-AR) agonist, induces skeletal muscle hypertrophy and slow-to-fast fiber-type transitions in mammalian species, but the mechanism and pathophysiological roles of these changes have not been explored."3.79Role of masseter muscle β₂-adrenergic signaling in regulation of muscle activity, myosin heavy chain transition, and hypertrophy. ( Cai, W; Fujita, T; Jin, HL; Kawai, N; Mototani, Y; Ohnuki, Y; Okumura, S; Saeki, Y; Shiozawa, K; Tanaka, E; Umeki, D, 2013)
"In this study we investigated the combined effect of myostatin (MSTN) suppression and β-agonist (clenbuterol) administration on muscle hypertrophy and the phosphorylation of muscle 4E-BP1 and p70S6k, two downstream effectors of the Akt/mTOR anabolic pathway."3.77The muscle-hypertrophic effect of clenbuterol is additive to the hypertrophic effect of myostatin suppression. ( Kim, KH; Kim, YS; Yang, J, 2011)
"Our data reveal that clenbuterol-induced skeletal muscle hypertrophy is unable to mimic the beneficial clinical effects of increased musculature derived through targeted strength training in humans, in a rodent model of MNX-induced OA."3.76Beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle does not modulate disease severity in the rodent meniscectomy model of osteoarthritis. ( Bardsley, R; Doherty, M; Jones, SW; Maciewicz, RA; Parr, T; Tonge, DP, 2010)
"Clenbuterol, a beta-adrenoceptor agonist, has been reported to induce skeletal muscle hypertrophy."3.74Ultrastructural findings for the mitochondrial subpopulation of mice skeletal muscle after adrenergic stimulation by clenbuterol. ( Sharma, S; Sundal, S, 2007)
"Certain beta(2)-adrenoceptor agonists, such as clenbuterol, are known to elicit a muscle-specific anabolism or hypertrophy in both normal and catabolic muscle in a wide variety of species."3.74Clenbuterol increases muscle fiber size and GATA-2 protein in rat skeletal muscle in utero. ( Delday, MI; Downie, D; Maltin, CA; Sneddon, AA, 2008)
"Clenbuterol (Clen), a beta(2)-agonist, is known to produce skeletal and myocardial hypertrophy."3.73Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle. ( Karbowska, J; Kochan, Z; Latif, N; Malik, A; Smolenski, RT; Soppa, GK; Terracciano, CM; Yacoub, MH; Yuen, AH, 2005)
" The regulatory mechanism for the hypertrophy of skeletal muscles induced by clenbuterol is unclear."3.73Transforming growth factor betas are upregulated in the rat masseter muscle hypertrophied by clenbuterol, a beta2 adrenergic agonist. ( Akutsu, S; Shimada, A; Yamane, A, 2006)
"Global evaluation of gene expression after administration of clenbuterol identified changes in gene expression and overrepresented functional categories of genes that may regulate BA-induced muscle hypertrophy."3.73Changes in skeletal muscle gene expression following clenbuterol administration. ( McDaneld, TG; McIntyre, LM; Spurlock, DM, 2006)
" We studied changes in MLC2 phosphorylation in rats receiving three treatment conditions causing slow-to-fast transitions: 1) atrophy induced by 14 days of hindlimb suspension (HS), 2) hypertrophy induced by 14 days of clenbuterol administration (CB), and 3) 14 days of combined treatment (CB-HS)."3.72Increased phosphorylation of myosin light chain associated with slow-to-fast transition in rat soleus. ( Bozzo, C; Mounier, Y; Reggiani, C; Stevens, L; Toniolo, L, 2003)
"The relationship between myogenin or MyoD expression and hypertrophy of the rat soleus produced either by clenbuterol and 3,3', 5-triiodo-L-thyronine (CT) treatment or by surgical overload was examined."3.70Myogenin, MyoD, and myosin expression after pharmacologically and surgically induced hypertrophy. ( Greaser, ML; Mozdziak, PE; Schultz, E, 1998)
" The beta 2-adrenoceptor agonist clenbuterol was used to investigate its potential to selectively induce skeletal muscle hypertrophy, particularly the latissimus dorsi muscle (LDM), independent of adverse effects on cardiac muscle."3.69Clenbuterol induces hypertrophy of the latissimus dorsi muscle and heart in the rat with molecular and phenotypic changes. ( Boheler, KR; Petrou, M; Wynne, DG; Yacoub, MH, 1995)
"The sympathomimetic agent, clenbuterol, induces a muscle-specific hypertrophy in both normal and catabolic muscle."3.68Satellite cells in innervated and denervated muscles treated with clenbuterol. ( Delday, MI; Maltin, CA, 1992)
" When rats were fed with clenbuterol for 7 days skeletal muscle mass increased by 21% in the tonic soleus and phasic plantaris muscles and a 16% hypertrophy of the heart was also induced."3.68Effects of the cyclo-oxygenase inhibitor, fenbufen, on clenbuterol-induced hypertrophy of cardiac and skeletal muscle of rats. ( Bain, P; Delday, MI; Maltin, CA; McMillan, DN; Noble, BS; Palmer, RM, 1990)
" Hypertrophy of soleus and plantaris muscles was induced either by severance of the tendon to the synergistic gastrocnemius (tenotomy) or by administration of the beta-adrenoceptor agonist clenbuterol."3.68Expression of c-myc and c-fos in rat skeletal muscle. Evidence for increased levels of c-myc mRNA during hypertrophy. ( Hesketh, JE; Whitelaw, PF, 1992)
" However, such doses may also induce myocyte death in the heart and skeletal muscles and hence may not be safe doses for humans."1.33Dose-dependent separation of the hypertrophic and myotoxic effects of the beta(2)-adrenergic receptor agonist clenbuterol in rat striated muscles. ( Burniston, JG; Clark, WA; Goldspink, DF; Tan, LB, 2006)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.76)18.7374
1990's10 (23.81)18.2507
2000's16 (38.10)29.6817
2010's12 (28.57)24.3611
2020's2 (4.76)2.80

Authors

AuthorsStudies
Tanaka, S1
Sugimoto, N1
Ohno-Shosaku, T1
Madokoro, S1
Inaoka, PT1
Yamazaki, T1
Kuramoto, N1
Nomura, K1
Kohno, D1
Kitamura, T1
Karsenty, G1
Hosooka, T1
Ogawa, W1
Kim, J1
Grotegut, CA1
Wisler, JW1
Li, T1
Mao, L1
Chen, M1
Chen, W1
Rosenberg, PB1
Rockman, HA1
Lefkowitz, RJ1
Ohnuki, Y3
Umeki, D3
Cai, W2
Kawai, N1
Mototani, Y3
Shiozawa, K3
Jin, HL1
Fujita, T3
Tanaka, E1
Saeki, Y3
Okumura, S3
Sumi, K1
Higashi, S1
Natsume, M1
Kawahata, K1
Nakazato, K1
Py, G3
Ramonatxo, C1
Sirvent, P1
Sanchez, AM1
Philippe, AG1
Douillard, A3
Galbès, O3
Lionne, C1
Bonnieu, A3
Chopard, A1
Cazorla, O1
Lacampagne, A1
Candau, RB1
Suita, K2
Nakamura, Y1
Nariyama, M1
Ito, A1
Kawamura, N1
Yagisawa, Y1
Jin, H1
Ishikawa, Y1
Woodall, BP1
Woodall, MC1
Luongo, TS1
Grisanti, LA1
Tilley, DG1
Elrod, JW1
Koch, WJ1
Sato, S1
Nomura, S1
Kawano, F1
Tanihata, J1
Tachiyashiki, K1
Imaizumi, K1
Tonge, DP1
Jones, SW1
Parr, T1
Bardsley, R1
Doherty, M1
Maciewicz, RA1
Rossano, B2
Vernus, B2
Candau, R2
Kim, KH1
Kim, YS1
Yang, J1
Begue, G1
Levin, J1
Abo, T1
Iida, RH1
Kaneko, S1
Suga, T1
Yamada, H1
Hamada, Y1
Yamane, A3
Bozzo, C1
Stevens, L2
Toniolo, L1
Mounier, Y2
Reggiani, C1
Oishi, Y1
Imoto, K1
Ogata, T1
Taniguchi, K1
Matsumoto, H1
Fukuoka, Y1
Roy, RR1
Soppa, GK1
Smolenski, RT1
Latif, N1
Yuen, AH1
Malik, A1
Karbowska, J1
Kochan, Z1
Terracciano, CM1
Yacoub, MH2
Akutsu, S2
Shimada, A2
Burniston, JG1
Clark, WA1
Tan, LB1
Goldspink, DF1
Matsumoto, T1
Wakana, N1
Morito, M1
Sundal, S2
Katoch, SS1
Sharma, S2
Shi, H1
Zeng, C1
Ricome, A1
Hannon, KM1
Grant, AL1
Gerrard, DE1
Spurlock, DM1
McDaneld, TG1
McIntyre, LM1
Downie, D1
Delday, MI4
Maltin, CA4
Sneddon, AA1
Rehfeldt, C1
Weikard, R1
Reichel, K1
Petrou, M1
Wynne, DG1
Boheler, KR1
Costelli, P1
García-Martínez, C1
Llovera, M1
Carbó, N1
López-Soriano, FJ1
Agell, N1
Tessitore, L1
Baccino, FM1
Argilés, JM1
Mozdziak, PE1
Greaser, ML1
Schultz, E1
Murphy, RJ1
Béliveau, L2
Gardiner, PF1
Calderone, A2
Rajab, P1
Fox, J1
Riaz, S1
Tomlinson, D1
Ball, D1
Greenhaff, PL1
Firinga, C1
Gohlsch, B1
Bastide, B1
Pette, D1
Lavoie, JL1
Hinkle, RT1
Hodge, KMB1
Cody, DB1
Sheldon, RJ1
Kobilka, BK1
Isfort, RJ1
Agbenyega, ET1
Wareham, AC1
Palmer, RM1
McMillan, DN1
Noble, BS1
Bain, P1
Whitelaw, PF1
Hesketh, JE1
Horne, Z1
Hesketh, J1
Hay, SM1
Smith, FG1
Lobley, GE1
Reeds, PJ1
MacLennan, PA1
Edwards, RH1

Other Studies

42 other studies available for clenbuterol and Hypertrophy

ArticleYear
Effects of long-term treatment with dietary theobromine on rat skeletal muscles.
    Molecular biology reports, 2022, Volume: 49, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Diet; Hypertrophy; Male; Muscle, Skeletal; Rats; Rat

2022
Role of PDK1 in skeletal muscle hypertrophy induced by mechanical load.
    Scientific reports, 2021, 02-10, Volume: 11, Issue:1

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adrenergic beta-Agonists; Animals; Cell Line; Clenbute

2021
β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility.
    Skeletal muscle, 2018, 12-27, Volume: 8, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; beta-Arrestin 1; Calcium Signaling; Cells, Cultured; C

2018
Role of masseter muscle β₂-adrenergic signaling in regulation of muscle activity, myosin heavy chain transition, and hypertrophy.
    Journal of pharmacological sciences, 2013, Sep-20, Volume: 123, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Central Nervous System; Clenbuterol; Electr

2013
Temporal changes in ERK phosphorylation are harmonious with 4E-BP1, but not p70S6K, during clenbuterol-induced hypertrophy in the rat gastrocnemius.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2014, Volume: 39, Issue:8

    Topics: Animals; Carrier Proteins; Clenbuterol; Extracellular Signal-Regulated MAP Kinases; Hypertrophy; Int

2014
Chronic clenbuterol treatment compromises force production without directly altering skeletal muscle contractile machinery.
    The Journal of physiology, 2015, Apr-15, Volume: 593, Issue:8

    Topics: Action Potentials; Adenosine Triphosphatases; Adrenergic beta-Agonists; Animals; Calcium; Clenbutero

2015
Protective Effects of Clenbuterol against Dexamethasone-Induced Masseter Muscle Atrophy and Myosin Heavy Chain Transition.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Clenbuterol; Dexamethasone; Energy Metabolism; Feeding B

2015
Role of phosphodiesterase 4 expression in the Epac1 signaling-dependent skeletal muscle hypertrophic action of clenbuterol.
    Physiological reports, 2016, Volume: 4, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Cyclic Nucleotide Phosphodiesterases, Type 4; Gene E

2016
Skeletal Muscle-specific G Protein-coupled Receptor Kinase 2 Ablation Alters Isolated Skeletal Muscle Mechanics and Enhances Clenbuterol-stimulated Hypertrophy.
    The Journal of biological chemistry, 2016, Oct-14, Volume: 291, Issue:42

    Topics: Animals; Clenbuterol; G-Protein-Coupled Receptor Kinase 2; Hypertrophy; Mice; Mice, Knockout; Muscle

2016
Effects of the beta2-agonist clenbuterol on beta1- and beta2-adrenoceptor mRNA expressions of rat skeletal and left ventricle muscles.
    Journal of pharmacological sciences, 2008, Volume: 107, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Gene Expression Regulation; Heart Ventricles; Hypert

2008
Beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle does not modulate disease severity in the rodent meniscectomy model of osteoarthritis.
    Osteoarthritis and cartilage, 2010, Volume: 18, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Body Weight; Clenbuterol; Disease Models, Animal; Hypertrophy; Ma

2010
Time course in calpain activity and autolysis in slow and fast skeletal muscle during clenbuterol treatment.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Autolysis; Calpain; Cell Death; Clenbuterol; Hypertrophy; Male; M

2011
The muscle-hypertrophic effect of clenbuterol is additive to the hypertrophic effect of myostatin suppression.
    Muscle & nerve, 2011, Volume: 43, Issue:5

    Topics: Anabolic Agents; Animals; Clenbuterol; Drug Synergism; Female; Hypertrophy; Mice; Mice, Inbred C57BL

2011
Calpastatin overexpression in the skeletal muscle of mice prevents clenbuterol-induced muscle hypertrophy and phenotypic shift.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:4

    Topics: Animals; Calcium-Binding Proteins; Calpain; Cattle; Clenbuterol; Gene Expression Regulation; Hypertr

2012
IGF and myostatin pathways are respectively induced during the earlier and the later stages of skeletal muscle hypertrophy induced by clenbuterol, a β₂-adrenergic agonist.
    Cell biochemistry and function, 2012, Volume: 30, Issue:8

    Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Blotting, Western; Clenbuterol; Hypertrophy

2012
Increased phosphorylation of myosin light chain associated with slow-to-fast transition in rat soleus.
    American journal of physiology. Cell physiology, 2003, Volume: 285, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Atrophy; Cardiac Myosins; Clenbuterol; Hindlimb Suspension; Hyper

2003
Calcineurin and heat-shock proteins modulation in clenbuterol-induced hypertrophied rat skeletal muscles.
    Pflugers Archiv : European journal of physiology, 2004, Volume: 448, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; Calcineurin; Clenbuterol; Drinking; Electropho

2004
Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:3

    Topics: Adrenergic beta-Agonists; Age Factors; Animals; Atrophy; Calcium; Carbohydrate Metabolism; Citric Ac

2005
Transforming growth factor betas are upregulated in the rat masseter muscle hypertrophied by clenbuterol, a beta2 adrenergic agonist.
    British journal of pharmacology, 2006, Volume: 147, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Body Weight; Clenbuterol; Fibroblast Growth Factors; Hepatocyte G

2006
Dose-dependent separation of the hypertrophic and myotoxic effects of the beta(2)-adrenergic receptor agonist clenbuterol in rat striated muscles.
    Muscle & nerve, 2006, Volume: 33, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Clenbuterol; Dose-Response Relationship, Drug; Hypertr

2006
The expressions of insulin-like growth factors, their receptors, and binding proteins are related to the mechanism regulating masseter muscle mass in the rat.
    Archives of oral biology, 2006, Volume: 51, Issue:7

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Hypertrophy; Insulin-Like Growth Factor Binding Prot

2006
Metabolic and physiologic characteristics of skeletal muscle determine its response to clenbuterol treatment.
    Indian journal of biochemistry & biophysics, 2006, Volume: 43, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Hypertrophy; Male; Mice; Muscle Fibers, Fast-Twitch;

2006
Extracellular signal-regulated kinase pathway is differentially involved in beta-agonist-induced hypertrophy in slow and fast muscles.
    American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Cell Cycle Proteins; Cell Line; Clenbuterol; Disease Models, Anim

2007
Ultrastructural findings for the mitochondrial subpopulation of mice skeletal muscle after adrenergic stimulation by clenbuterol.
    The journal of physiological sciences : JPS, 2007, Volume: 57, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Diaphragm; Hypertrophy; Male; Mice; Microscopy, Elec

2007
Changes in skeletal muscle gene expression following clenbuterol administration.
    BMC genomics, 2006, Dec-20, Volume: 7

    Topics: Adrenergic beta-Agonists; Animals; Blood Urea Nitrogen; Carrier Proteins; Clenbuterol; Cyclin-Depend

2006
Clenbuterol increases muscle fiber size and GATA-2 protein in rat skeletal muscle in utero.
    Molecular reproduction and development, 2008, Volume: 75, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Cell Size; Clenbuterol; Female; Fetus; GATA2 Transcription Factor

2008
[The effect of the beta-adrenergic agonist clenbuterol on the growth of skeletal muscles of rats].
    Archiv fur Tierernahrung, 1994, Volume: 45, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; DNA; Female; Hindlimb; Hypertrophy; Male; Muscle Dev

1994
Clenbuterol induces hypertrophy of the latissimus dorsi muscle and heart in the rat with molecular and phenotypic changes.
    Circulation, 1995, Nov-01, Volume: 92, Issue:9 Suppl

    Topics: Adipose Tissue; Animals; Base Sequence; Body Weight; Cardiomegaly; Clenbuterol; Forelimb; Hypertroph

1995
Muscle protein waste in tumor-bearing rats is effectively antagonized by a beta 2-adrenergic agonist (clenbuterol). Role of the ATP-ubiquitin-dependent proteolytic pathway.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:5

    Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Ascites; Clenbuterol; Corticosterone; Hypertr

1995
Myogenin, MyoD, and myosin expression after pharmacologically and surgically induced hypertrophy.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Blotting, Northern; Body Weight; Clenbuterol; Female; Hypertro

1998
Nifedipine does not impede clenbuterol-stimulated muscle hypertrophy.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 221, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Calcium; Calcium Channels; Calcium C

1999
Skeletal muscle myosin heavy chain isoforms and energy metabolism after clenbuterol treatment in the rat.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Clenbuterol; Energ

2000
Effects of unweighting and clenbuterol on myosin light and heavy chains in fast and slow muscles of rat.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Atrophy; Body Weight; Clenbuterol; Hindlimb; Hindlimb Suspension;

2000
A farnesyltransferase inhibitor attenuated beta-adrenergic receptor downregulation in rat skeletal muscle.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:1

    Topics: Adrenergic beta-Agonists; Alkyl and Aryl Transferases; Animals; Animals, Newborn; Body Weight; Cells

2002
Skeletal muscle hypertrophy and anti-atrophy effects of clenbuterol are mediated by the beta2-adrenergic receptor.
    Muscle & nerve, 2002, Volume: 25, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Female; Hypertrophy; Male; Mice; Mice, Knockout; Mus

2002
Effect of clenbuterol on skeletal muscle atrophy in mice induced by the glucocorticoid dexamethasone.
    Comparative biochemistry and physiology. Comparative physiology, 1992, Volume: 102, Issue:1

    Topics: Animals; Clenbuterol; Dexamethasone; Hypertrophy; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; M

1992
Satellite cells in innervated and denervated muscles treated with clenbuterol.
    Muscle & nerve, 1992, Volume: 15, Issue:8

    Topics: Animals; Cell Division; Clenbuterol; Hypertrophy; Male; Microscopy, Electron; Muscle Denervation; Mu

1992
Effects of the cyclo-oxygenase inhibitor, fenbufen, on clenbuterol-induced hypertrophy of cardiac and skeletal muscle of rats.
    British journal of pharmacology, 1990, Volume: 101, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiomegaly; Clenbuterol; Cyclooxygenase Inhibito

1990
Expression of c-myc and c-fos in rat skeletal muscle. Evidence for increased levels of c-myc mRNA during hypertrophy.
    The Biochemical journal, 1992, Jan-01, Volume: 281 ( Pt 1)

    Topics: Aging; Animals; Blotting, Northern; Clenbuterol; Female; Gene Expression; Genes, fos; Genes, myc; Hy

1992
Increased association of ribosomes with myofibrils during the skeletal-muscle hypertrophy induced either by the beta-adrenoceptor agonist clenbuterol or by tenotomy.
    The Biochemical journal, 1990, Dec-15, Volume: 272, Issue:3

    Topics: Animals; Antibodies; Clenbuterol; Hypertrophy; Male; Muscles; Myofibrils; Rats; Rats, Inbred Strains

1990
The effect of the anabolic agent, clenbuterol, on overloaded rat skeletal muscle.
    Bioscience reports, 1987, Volume: 7, Issue:2

    Topics: Animals; Calcium-Transporting ATPases; Clenbuterol; Ethanolamines; Hindlimb; Hypertrophy; Muscle Pro

1987
Effects of clenbuterol and propranolol on muscle mass. Evidence that clenbuterol stimulates muscle beta-adrenoceptors to induce hypertrophy.
    The Biochemical journal, 1989, Dec-01, Volume: 264, Issue:2

    Topics: Animals; Body Composition; Clenbuterol; Cyclic AMP; Ethanolamines; Female; Glycogen; Heart; Hypertro

1989