Page last updated: 2024-10-25

clenbuterol and Equine Diseases

clenbuterol has been researched along with Equine Diseases in 25 studies

Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.

Research Excerpts

ExcerptRelevanceReference
"The present study was carried out to ascertain whether beta2-adrenergic receptor stimulation with clenbuterol would attenuate the pulmonary arterial, capillary and venous hypertension in horses performing high-intensity exercise and, in turn, modify the occurrence of exercise-induced pulmonary haemorrhage (EIPH)."9.09Clenbuterol administration does not attenuate the exercise-induced pulmonary arterial, capillary or venous hypertension in strenuously exercising Thoroughbred horses. ( Goetz, TE; Humphrey, S; Manohar, M; Rothenbaum, P, 2000)
"A clinical study about the effects of a beta 2-mimetic agent (Clenbuterol) in mares with pregnancy disorders or disorders during the periparturient period (n = 34) is reported."7.67[The use of a beta 2-mimetic agent (clenbuterol) in equine pregnancy disorders and obstetrics]. ( Bostedt, H, 1988)
" Measurements were made at base line and after saline solution or clenbuterol was administered IV at a dosage of 0."5.27Effect of clenbuterol on histamine-induced airway obstruction in ponies. ( Derksen, FJ; Robinson, NE; Scott, JS; Slocombe, RF, 1987)
"The concentration of histamine required to increase total airway obstruction by 35% (PC35) was significantly reduced during treatment with clenbuterol (mean change, 11."5.16Effect of prolonged administration of clenbuterol on airway reactivity and sweating in horses with inflammatory airway disease. ( Abraham, G; Bauquier, SH; Boston, RC; Nolen-Walston, RD; Read, JR; Soma, LR, 2012)
"The present study was carried out to ascertain whether beta2-adrenergic receptor stimulation with clenbuterol would attenuate the pulmonary arterial, capillary and venous hypertension in horses performing high-intensity exercise and, in turn, modify the occurrence of exercise-induced pulmonary haemorrhage (EIPH)."5.09Clenbuterol administration does not attenuate the exercise-induced pulmonary arterial, capillary or venous hypertension in strenuously exercising Thoroughbred horses. ( Goetz, TE; Humphrey, S; Manohar, M; Rothenbaum, P, 2000)
"Bacteria were infused into the uteri of 5 estrous mares resistant to persistent mating-induced endometritis, first during a control cycle, and then during treatment with clenbuterol, a beta 2 agonist."3.70Uterine contractility is necessary for the clearance of intrauterine fluid but not bacteria after bacterial infusion in the mare. ( Nikolakopoulos, E; Watson, ED, 1999)
"A clinical study about the effects of a beta 2-mimetic agent (Clenbuterol) in mares with pregnancy disorders or disorders during the periparturient period (n = 34) is reported."3.67[The use of a beta 2-mimetic agent (clenbuterol) in equine pregnancy disorders and obstetrics]. ( Bostedt, H, 1988)
" with clenbuterol (as Ventipulmin Syrup), beginning with the lowest dosage of 0."2.67Clinical efficacy and safety of clenbuterol HCl when administered to effect in horses with chronic obstructive pulmonary disease (COPD). ( Aviad, AD; Erichsen, DF; Kennedy, TJ; Schultz, RH, 1994)
"Clenbuterol is a beta(2)-agonist and potent selective bronchodilator that is used to treat bronchospasm in the horse."2.45Clenbuterol and the horse revisited. ( Kearns, CF; McKeever, KH, 2009)
"Clenbuterol is a β(2)-adrenergic receptor agonist licensed for veterinary use as a bronchodilator."1.37Clenbuterol toxicosis in three Quarter Horse racehorses after administration of a compounded product. ( Barker, SA; Bauer, RW; McConnico, RS; Mirza, MH; Morgan, TW; Thompson, JA, 2011)
"Clenbuterol hydrochloride was used as a tocolytic agent in 9 mares with uterine displacement, abortus imminens and post-operative uterine torsion and 3 mares aborted during treatment."1.29Review of 115 cases of colic in the pregnant mare. ( Boening, KJ; Leendertse, IP, 1993)
"Oral clenbuterol was effective in only seven of 15 cases."1.29Obstructive pulmonary disease in 18 horses at summer pasture. ( Mair, TS, 1996)
" Measurements were made at base line and after saline solution or clenbuterol was administered IV at a dosage of 0."1.27Effect of clenbuterol on histamine-induced airway obstruction in ponies. ( Derksen, FJ; Robinson, NE; Scott, JS; Slocombe, RF, 1987)
" NAB 365 administered at a dosage of 0."1.26[Veterinary and clinical experience of the use of a beta2-receptor-stimulating sympathicomimetic agent (NAB 365) in horses with respiratory discase (author's transl)]. ( Hajer, R; Sasse, HH, 1977)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's8 (32.00)18.2507
2000's9 (36.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cudmore, LA1
Muurlink, T1
Whittem, T1
Bailey, SR1
Kearns, CF1
McKeever, KH1
Roberts, CA1
Thompson, JA1
Mirza, MH1
Barker, SA1
Morgan, TW1
Bauer, RW1
McConnico, RS1
Read, JR1
Boston, RC1
Abraham, G1
Bauquier, SH1
Soma, LR1
Nolen-Walston, RD1
Sander, K1
Deegen, E1
Ohnesorge, B1
Kolm, G1
Gemeiner, M2
Deichsel, K1
Budik, S1
Aurich, J1
Aurich, C1
Laan, TT2
Bull, S2
Pirie, RS1
Fink-Gremmels, J2
van Nieuwstadt, RA1
van den Hoven, R1
Duvigneau, JC1
Hartl, RT1
Breuer, D1
Becker, M1
Boening, KJ1
Leendertse, IP1
Derksen, FJ2
Erichsen, DF1
Aviad, AD1
Schultz, RH1
Kennedy, TJ1
Mair, TS1
Kästner, SB1
Haines, DM1
Archer, J1
Townsend, HG1
Nikolakopoulos, E1
Watson, ED1
Manohar, M1
Goetz, TE1
Rothenbaum, P1
Humphrey, S1
Harkins, JD1
Robinson, NE2
Woods, WE1
Lehner, AF1
Smith, MD1
Gates, RS1
Fisher, M1
Tobin, T1
Sasse, HH2
Hajer, R1
Traub-Dargatz, JL1
McKinnon, AO1
Thrall, MA1
Jones, RL1
Bruyninckx, W1
Blancquaert, AM1
Dargatz, DA1
Hackett, IJ1
Turgut, K1
Bostedt, H1
Scott, JS1
Slocombe, RF1

Reviews

1 review available for clenbuterol and Equine Diseases

ArticleYear
Clenbuterol and the horse revisited.
    Veterinary journal (London, England : 1997), 2009, Volume: 182, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Bronchial Diseases; Clenbuterol; Dose-Response Relationship, Drug

2009

Trials

5 trials available for clenbuterol and Equine Diseases

ArticleYear
Effect of prolonged administration of clenbuterol on airway reactivity and sweating in horses with inflammatory airway disease.
    American journal of veterinary research, 2012, Volume: 73, Issue:1

    Topics: Airway Obstruction; Animals; Bronchodilator Agents; Clenbuterol; Cross-Over Studies; Dose-Response R

2012
Clenbuterol affects the expression of messenger RNA for interleukin 10 in peripheral leukocytes from horses challenged intrabronchially with lipopolysaccharides.
    Veterinary research communications, 2006, Volume: 30, Issue:8

    Topics: Animals; Bronchodilator Agents; Clenbuterol; Gene Expression Regulation; Horse Diseases; Horses; Int

2006
Clinical efficacy and safety of clenbuterol HCl when administered to effect in horses with chronic obstructive pulmonary disease (COPD).
    Equine veterinary journal, 1994, Volume: 26, Issue:4

    Topics: Animals; Bronchodilator Agents; Clenbuterol; Dose-Response Relationship, Drug; Female; Horse Disease

1994
Investigations on the ability of clenbuterol hydrochloride to reduce clinical signs and inflammation associated with equine influenza A infection.
    Equine veterinary journal, 1999, Volume: 31, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Clenbuterol

1999
Clenbuterol administration does not attenuate the exercise-induced pulmonary arterial, capillary or venous hypertension in strenuously exercising Thoroughbred horses.
    Equine veterinary journal, 2000, Volume: 32, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Clenbuterol; Female; Hemorrhage; Horse Diseases; Horses; Hyperten

2000

Other Studies

19 other studies available for clenbuterol and Equine Diseases

ArticleYear
Effects of oral clenbuterol on the clinical and inflammatory response to endotoxaemia in the horse.
    Research in veterinary science, 2013, Volume: 94, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Body Temperature; Clenbuterol; Endotoxemia;

2013
The impact of long-term clenbuterol on athletic performance in horses.
    Veterinary journal (London, England : 1997), 2009, Volume: 182, Issue:3

    Topics: Animals; Clenbuterol; Horse Diseases; Horses; Physical Conditioning, Animal; Sympathomimetics; Time

2009
Clenbuterol toxicosis in three Quarter Horse racehorses after administration of a compounded product.
    Journal of the American Veterinary Medical Association, 2011, Sep-15, Volume: 239, Issue:6

    Topics: Animals; Chromatography, Liquid; Clenbuterol; Drug Compounding; Drug Overdose; Fluid Therapy; Horse

2011
[Influencing respiratory gas analytical lung function parameters by intravenous injection of clenbuterol in horses with chronic lung diseases].
    DTW. Deutsche tierarztliche Wochenschrift, 2002, Volume: 109, Issue:7

    Topics: Animals; Bronchodilator Agents; Carbon Dioxide; Clenbuterol; Female; Horse Diseases; Horses; Injecti

2002
Effect of clenbuterol on the clearance of particles of charcoal (4 to 90 microm) from the uteri of mares.
    The Veterinary record, 2005, Feb-26, Volume: 156, Issue:9

    Topics: Animals; Charcoal; Clenbuterol; Endometriosis; Estrus; Female; Horse Diseases; Horses; Infusions, In

2005
The anti-inflammatory effects of IV administered clenbuterol in horses with recurrent airway obstruction.
    Veterinary journal (London, England : 1997), 2006, Volume: 171, Issue:3

    Topics: Animals; Antigens, Fungal; Aspergillus fumigatus; Bronchoalveolar Lavage Fluid; Bronchodilator Agent

2006
The effect of aerosolized and intravenously administered clenbuterol and aerosolized fluticasone propionate on horses challenged with Aspergillus fumigatus antigen.
    Veterinary research communications, 2006, Volume: 30, Issue:6

    Topics: Administration, Inhalation; Androstadienes; Animals; Antigens, Fungal; Aspergillus fumigatus; Bronch

2006
[Acetylcysteine (Fluimucil) in the treatment of COPD of the horse].
    Tierarztliche Praxis, 1983, Volume: 11, Issue:2

    Topics: Acetylcysteine; Administration, Oral; Animals; Clenbuterol; Drug Therapy, Combination; Female; Horse

1983
Review of 115 cases of colic in the pregnant mare.
    Equine veterinary journal, 1993, Volume: 25, Issue:6

    Topics: Abortion, Veterinary; Animals; Clenbuterol; Colic; Female; Horse Diseases; Horses; Pregnancy; Pregna

1993
Anecdotes and clinical trials: the story of clenbuterol.
    Equine veterinary journal, 1994, Volume: 26, Issue:4

    Topics: Anecdotes as Topic; Animals; Bronchodilator Agents; Clenbuterol; Clinical Trials as Topic; Horse Dis

1994
Obstructive pulmonary disease in 18 horses at summer pasture.
    The Veterinary record, 1996, Jan-27, Volume: 138, Issue:4

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Bronchodilato

1996
Uterine contractility is necessary for the clearance of intrauterine fluid but not bacteria after bacterial infusion in the mare.
    Theriogenology, 1999, Volume: 52, Issue:3

    Topics: Animals; Bacteria; Clenbuterol; Endometritis; Estrus; Female; Horse Diseases; Horses; Muscle Contrac

1999
Intratracheal clenbuterol in the horse: its pharmacological efficacy and analytical detection.
    Journal of veterinary pharmacology and therapeutics, 2000, Volume: 23, Issue:4

    Topics: Administration, Inhalation; Animals; Bronchodilator Agents; Clenbuterol; Enzyme-Linked Immunosorbent

2000
[Veterinary and clinical experience of the use of a beta2-receptor-stimulating sympathicomimetic agent (NAB 365) in horses with respiratory discase (author's transl)].
    Tijdschrift voor diergeneeskunde, 1977, Nov-01, Volume: 102, Issue:21

    Topics: Adrenergic beta-Agonists; Animals; Bronchodilator Agents; Clenbuterol; Drug Evaluation; Ethanolamine

1977
Evaluation of clinical signs of disease, bronchoalveolar and tracheal wash analysis, and arterial blood gas tensions in 13 horses with chronic obstructive pulmonary disease treated with prednisone, methyl sulfonmethane, and clenbuterol hydrochloride.
    American journal of veterinary research, 1992, Volume: 53, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Carbon Dioxide; Clen

1992
Oil seed rape and equine respiratory disease.
    The Veterinary record, 1990, Jul-14, Volume: 127, Issue:2

    Topics: Animals; Brassica; Clenbuterol; Horse Diseases; Horses; Lung Diseases, Obstructive

1990
Influence of clenbuterol on mucociliary transport in healthy horses and horses with chronic obstructive pulmonary disease.
    The Veterinary record, 1989, Nov-18, Volume: 125, Issue:21

    Topics: Animals; Clenbuterol; Ethanolamines; Female; Horse Diseases; Horses; Lung Diseases, Obstructive; Mal

1989
[The use of a beta 2-mimetic agent (clenbuterol) in equine pregnancy disorders and obstetrics].
    Tierarztliche Praxis, 1988, Volume: 16, Issue:1

    Topics: Animals; Clenbuterol; Ethanolamines; Female; Horse Diseases; Horses; Obstetric Labor Complications;

1988
Effect of clenbuterol on histamine-induced airway obstruction in ponies.
    American journal of veterinary research, 1987, Volume: 48, Issue:3

    Topics: Airway Obstruction; Animals; Clenbuterol; Dose-Response Relationship, Drug; Ethanolamines; Female; H

1987