Page last updated: 2024-10-25

clenbuterol and Brain Ischemia

clenbuterol has been researched along with Brain Ischemia in 6 studies

Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Combinations of memantine with clenbuterol extend the respective therapeutic window and provide synergistic cerebroprotective effects after stroke."7.72Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol. ( Culmsee, C; Junker, V; Kremers, W; Krieglstein, J; Plesnila, N; Thal, S, 2004)
"Combinations of memantine with clenbuterol extend the respective therapeutic window and provide synergistic cerebroprotective effects after stroke."3.72Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol. ( Culmsee, C; Junker, V; Kremers, W; Krieglstein, J; Plesnila, N; Thal, S, 2004)
"In a model of focal cerebral ischemia in mice the cerebroprotective effect of clenbuterol (0."1.31Stimulation of beta-adrenoceptors activates astrocytes and provides neuroprotection. ( Becker, A; Culmsee, C; Hühne, R; Junker, V; Krieglstein, J; Ravati, A; Zembatov, M, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
García-Esperón, C1
Hervás-García, JV1
Jiménez-González, M1
Pérez de la Ossa-Herrero, N1
Gomis-Cortina, M1
Dorado-Bouix, L1
López-Cancio Martinez, E1
Castaño-Duque, CH1
Millán-Torné, M1
Dávalos, A1
Rami, A2
Volkmann, T1
Agarwal, R1
Schoninger, S1
Nürnberger, F1
Saido, TC1
Winckler, J1
Culmsee, C3
Junker, V3
Kremers, W2
Thal, S2
Plesnila, N2
Krieglstein, J4
Maier, S1
Schneider, HJ1
Semkova, I1
Schilling, M1
Henrich-Noack, P1
Becker, A1
Hühne, R1
Zembatov, M1
Ravati, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Memantine for Enhanced Stroke Recovery[NCT02144584]Early Phase 120 participants (Anticipated)Interventional2014-01-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for clenbuterol and Brain Ischemia

ArticleYear
[Ingestion of anabolic steroids and ischaemic stroke. A clinical case report and review of the literature].
    Revista de neurologia, 2013, Mar-16, Volume: 56, Issue:6

    Topics: Adult; Alcoholism; Anabolic Agents; Brain Ischemia; Cerebral Angiography; Clenbuterol; Doping in Spo

2013

Other Studies

5 other studies available for clenbuterol and Brain Ischemia

ArticleYear
beta2-Adrenergic receptor responsiveness of the calpain-calpastatin system and attenuation of neuronal death in rat hippocampus after transient global ischemia.
    Neuroscience research, 2003, Volume: 47, Issue:4

    Topics: Animals; Apoptosis; Blotting, Western; Brain Ischemia; Calcium-Binding Proteins; Calpain; Clenbutero

2003
Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol.
    Stroke, 2004, Volume: 35, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Brain Ischemia; Cells, Cultured; Clenbuterol; Disease Models, Ani

2004
Enantio-selective effects of clenbuterol in cultured neurons and astrocytes, and in a mouse model of cerebral ischemia.
    European journal of pharmacology, 2007, Dec-01, Volume: 575, Issue:1-3

    Topics: Adrenergic beta-Agonists; Animals; Astrocytes; Blood Glucose; Blood Pressure; Brain Ischemia; Cells,

2007
Clenbuterol protects mouse cerebral cortex and rat hippocampus from ischemic damage and attenuates glutamate neurotoxicity in cultured hippocampal neurons by induction of NGF.
    Brain research, 1996, Apr-22, Volume: 717, Issue:1-2

    Topics: Animals; Animals, Newborn; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Clenbuterol; Glutamic A

1996
Stimulation of beta-adrenoceptors activates astrocytes and provides neuroprotection.
    European journal of pharmacology, 2002, Jun-20, Volume: 446, Issue:1-3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Brain Ischemia; Cell Dea

2002