clenbuterol has been researched along with Brain Ischemia in 6 studies
Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combinations of memantine with clenbuterol extend the respective therapeutic window and provide synergistic cerebroprotective effects after stroke." | 7.72 | Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol. ( Culmsee, C; Junker, V; Kremers, W; Krieglstein, J; Plesnila, N; Thal, S, 2004) |
| "Combinations of memantine with clenbuterol extend the respective therapeutic window and provide synergistic cerebroprotective effects after stroke." | 3.72 | Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol. ( Culmsee, C; Junker, V; Kremers, W; Krieglstein, J; Plesnila, N; Thal, S, 2004) |
| "In a model of focal cerebral ischemia in mice the cerebroprotective effect of clenbuterol (0." | 1.31 | Stimulation of beta-adrenoceptors activates astrocytes and provides neuroprotection. ( Becker, A; Culmsee, C; Hühne, R; Junker, V; Krieglstein, J; Ravati, A; Zembatov, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Esperón, C | 1 |
| Hervás-García, JV | 1 |
| Jiménez-González, M | 1 |
| Pérez de la Ossa-Herrero, N | 1 |
| Gomis-Cortina, M | 1 |
| Dorado-Bouix, L | 1 |
| López-Cancio Martinez, E | 1 |
| Castaño-Duque, CH | 1 |
| Millán-Torné, M | 1 |
| Dávalos, A | 1 |
| Rami, A | 2 |
| Volkmann, T | 1 |
| Agarwal, R | 1 |
| Schoninger, S | 1 |
| Nürnberger, F | 1 |
| Saido, TC | 1 |
| Winckler, J | 1 |
| Culmsee, C | 3 |
| Junker, V | 3 |
| Kremers, W | 2 |
| Thal, S | 2 |
| Plesnila, N | 2 |
| Krieglstein, J | 4 |
| Maier, S | 1 |
| Schneider, HJ | 1 |
| Semkova, I | 1 |
| Schilling, M | 1 |
| Henrich-Noack, P | 1 |
| Becker, A | 1 |
| Hühne, R | 1 |
| Zembatov, M | 1 |
| Ravati, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Memantine for Enhanced Stroke Recovery[NCT02144584] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2014-01-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for clenbuterol and Brain Ischemia
| Article | Year |
|---|---|
[Ingestion of anabolic steroids and ischaemic stroke. A clinical case report and review of the literature].
Topics: Adult; Alcoholism; Anabolic Agents; Brain Ischemia; Cerebral Angiography; Clenbuterol; Doping in Spo | 2013 |
5 other studies available for clenbuterol and Brain Ischemia
| Article | Year |
|---|---|
beta2-Adrenergic receptor responsiveness of the calpain-calpastatin system and attenuation of neuronal death in rat hippocampus after transient global ischemia.
Topics: Animals; Apoptosis; Blotting, Western; Brain Ischemia; Calcium-Binding Proteins; Calpain; Clenbutero | 2003 |
Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol.
Topics: Adrenergic beta-Agonists; Animals; Brain Ischemia; Cells, Cultured; Clenbuterol; Disease Models, Ani | 2004 |
Enantio-selective effects of clenbuterol in cultured neurons and astrocytes, and in a mouse model of cerebral ischemia.
Topics: Adrenergic beta-Agonists; Animals; Astrocytes; Blood Glucose; Blood Pressure; Brain Ischemia; Cells, | 2007 |
Clenbuterol protects mouse cerebral cortex and rat hippocampus from ischemic damage and attenuates glutamate neurotoxicity in cultured hippocampal neurons by induction of NGF.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Clenbuterol; Glutamic A | 1996 |
Stimulation of beta-adrenoceptors activates astrocytes and provides neuroprotection.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Brain Ischemia; Cell Dea | 2002 |