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clenbuterol and Atrophy

clenbuterol has been researched along with Atrophy in 9 studies

Clenbuterol: A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
clenbuterol : A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Clenbuterol (Clen), a beta(2)-agonist, is known to produce skeletal and myocardial hypertrophy."3.73Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle. ( Karbowska, J; Kochan, Z; Latif, N; Malik, A; Smolenski, RT; Soppa, GK; Terracciano, CM; Yacoub, MH; Yuen, AH, 2005)
"During complete LV unloading, clenbuterol did not prevent myocardial atrophy but improved gene expression (SERCA2a, beta-MHC) and beta-adrenergic responsiveness and potentially prevented myocardial apoptosis."3.73Does the beta2-agonist clenbuterol help to maintain myocardial potential to recover during mechanical unloading? ( Ikeda, T; Kanemitsu, H; Komeda, M; Matsuoka, S; Nishina, T; Oriyanhan, W; Shiina, R; Tsuneyoshi, H, 2005)
" We studied changes in MLC2 phosphorylation in rats receiving three treatment conditions causing slow-to-fast transitions: 1) atrophy induced by 14 days of hindlimb suspension (HS), 2) hypertrophy induced by 14 days of clenbuterol administration (CB), and 3) 14 days of combined treatment (CB-HS)."3.72Increased phosphorylation of myosin light chain associated with slow-to-fast transition in rat soleus. ( Bozzo, C; Mounier, Y; Reggiani, C; Stevens, L; Toniolo, L, 2003)
"Heart failure is a widespread condition in the United States that is predicted to significantly increase in prevalence in the next decade."2.61Left ventricular assist device recovery: does duration of mechanical support matter? ( Chaparro, SV; Pham, BN, 2019)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pham, BN1
Chaparro, SV1
Pokorný, M1
Cervenka, L1
Netuka, I1
Pirk, J1
Koňařík, M1
Malý, J1
Bozzo, C1
Stevens, L3
Toniolo, L1
Mounier, Y2
Reggiani, C2
Pellegrino, MA1
D'Antona, G1
Bortolotto, S1
Boschi, F1
Pastoris, O1
Bottinelli, R1
Polla, B1
Soppa, GK1
Smolenski, RT1
Latif, N1
Yuen, AH1
Malik, A1
Karbowska, J1
Kochan, Z1
Terracciano, CM1
Yacoub, MH1
Tsuneyoshi, H1
Oriyanhan, W1
Kanemitsu, H1
Shiina, R1
Nishina, T1
Matsuoka, S1
Ikeda, T1
Komeda, M1
Firinga, C1
Gohlsch, B1
Bastide, B1
Pette, D1
Canu, M1
Ricart-Firinga, C1
Picquet, F1
Falempin, M1
Zeman, RJ1
Ludemann, R1
Etlinger, JD1

Reviews

2 reviews available for clenbuterol and Atrophy

ArticleYear
Left ventricular assist device recovery: does duration of mechanical support matter?
    Heart failure reviews, 2019, Volume: 24, Issue:2

    Topics: Adult; Atrophy; Calcium; Cardiomyopathy, Dilated; Clenbuterol; Female; Heart; Heart Failure; Heart T

2019
Ventricular assist devices in heart failure: how to support the heart but prevent atrophy?
    Physiological research, 2014, Volume: 63, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Atrophy; Clenbuterol; Heart Failure; Heart-Assist Devices; Humans

2014

Other Studies

7 other studies available for clenbuterol and Atrophy

ArticleYear
Increased phosphorylation of myosin light chain associated with slow-to-fast transition in rat soleus.
    American journal of physiology. Cell physiology, 2003, Volume: 285, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Atrophy; Cardiac Myosins; Clenbuterol; Hindlimb Suspension; Hyper

2003
Clenbuterol antagonizes glucocorticoid-induced atrophy and fibre type transformation in mice.
    Experimental physiology, 2004, Volume: 89, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Atrophy; Clenbuterol; Dexamethasone; Diaphragm; Drug Interactions

2004
Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:3

    Topics: Adrenergic beta-Agonists; Age Factors; Animals; Atrophy; Calcium; Carbohydrate Metabolism; Citric Ac

2005
Does the beta2-agonist clenbuterol help to maintain myocardial potential to recover during mechanical unloading?
    Circulation, 2005, Aug-30, Volume: 112, Issue:9 Suppl

    Topics: Adrenergic beta-Agonists; Animals; Atrophy; Calcium-Transporting ATPases; Caspase 3; Caspases; Clenb

2005
Effects of unweighting and clenbuterol on myosin light and heavy chains in fast and slow muscles of rat.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Atrophy; Body Weight; Clenbuterol; Hindlimb; Hindlimb Suspension;

2000
Effect of the beta(2)-agonist clenbuterol on the locomotor activity of rat submitted to a 14-day period of hypodynamia-hypokinesia.
    Behavioural brain research, 2001, Volume: 122, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Atrophy; Clenbuterol; Electromyography; Hindlimb Suspension; Male

2001
Clenbuterol, a beta 2-agonist, retards atrophy in denervated muscles.
    The American journal of physiology, 1987, Volume: 252, Issue:1 Pt 1

    Topics: Animals; Atrophy; Clenbuterol; Ethanolamines; Female; Isometric Contraction; Muscle Denervation; Mus

1987