clemizole has been researched along with Disease Models, Animal in 5 studies
clemizole: was heading 1966-94 (see under BENZIMIDAZOLES 1966-90); use BENZIMIDAZOLES to search CLEMIZOLE 1966-94; a histamine H1- blocker used to treat allergies
clemizole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a pyrrolidin-1-ylmethyl and a 4-chlorobenzyl groups at positions 2 and 1 respectively.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dravet syndrome is a catastrophic childhood epilepsy with early-onset seizures, delayed language and motor development, sleep disturbances, anxiety-like behaviour, severe cognitive deficit and an increased risk of fatality." | 5.46 | Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome. ( Baraban, SC; Griffin, A; Hamling, KR; Hong, S; Knupp, K; Lee, LP, 2017) |
| "Clemizole and trazodone were previously identified in a larval zebrafish model for Dravet syndrome." | 1.72 | Clemizole and trazodone are effective antiseizure treatments in a zebrafish model of STXBP1 disorder. ( Baraban, SC; Moog, M, 2022) |
| "Dravet syndrome is a catastrophic childhood epilepsy with early-onset seizures, delayed language and motor development, sleep disturbances, anxiety-like behaviour, severe cognitive deficit and an increased risk of fatality." | 1.46 | Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome. ( Baraban, SC; Griffin, A; Hamling, KR; Hong, S; Knupp, K; Lee, LP, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Moog, M | 1 |
| Baraban, SC | 2 |
| Neff, EP | 1 |
| Griffin, A | 1 |
| Hamling, KR | 1 |
| Knupp, K | 1 |
| Hong, S | 1 |
| Lee, LP | 1 |
5 other studies available for clemizole and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Clemizole and trazodone are effective antiseizure treatments in a zebrafish model of STXBP1 disorder.
Topics: Animals; Anticonvulsants; Benzimidazoles; Disease Models, Animal; Humans; Larva; Munc18 Proteins; Ra | 2022 |
A new school of drug discovery.
Topics: Animals; Anti-Obesity Agents; Anticonvulsants; Benzazepines; Benzimidazoles; Disease Models, Animal; | 2017 |
Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome.
Topics: Adolescent; Animals; Animals, Genetically Modified; Anticonvulsants; Benzazepines; Benzimidazoles; C | 2017 |