clay and Dentin--Secondary

Calcium aluminate cements have shown little affinity for bacterial growth, low toxicity, and immunogenicity when used as a restoration material, but calcium aluminate cements have not been tested in vivo in pulpotomy procedures.. To address this question, a calcium aluminosilicate cement (Quick-Set) was tested along with 2 mineral trioxide aggregates, ProRoot MTA and MTA Plus. These cements were used as a capping agent after pulpotomy. Control rats had no pulpotomy, or the pulpotomy was not capped. Proinflammatory cytokines interleukin (IL)-1β and IL-1α were measured, and histology was performed at 30 and 60 days after capping. The nociceptive response was determined by measuring the lengthening of the rat's meal duration.. and. IL-1β and IL-1α concentrations were reduced in the capped teeth, but no differences were observed among the 3 cements. Dentinal bridging could be detected at both 30 and 60 days with each of the 3 cements, and the pulps were still vital 60 days after capping. Meal duration significantly shortened after placement of the 3 different cements, indicating a nociceptive response, but there were no differences among the materials. Calcium aluminosilicate cement had similar properties to mineral trioxide aggregates and is a viable option for pulpotomy procedures.

Topics: Aluminum Compounds; Aluminum Silicates; Animals; Bacterial Load; Calcium Compounds; Clay; Dental Cements; Dental Pulp; Dentin, Secondary; Drug Combinations; Eating; Inflammation Mediators; Interleukin-1alpha; Interleukin-1beta; Materials Testing; Nociception; Oxides; Pulp Capping and Pulpectomy Agents; Pulpotomy; Rats; Silicates; Time Factors; Tissue Survival