Page last updated: 2024-08-23

clavulanic acid and Middle Ear Inflammation

clavulanic acid has been researched along with Middle Ear Inflammation in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (7.69)	18.7374
1990's	19 (48.72)	18.2507
2000's	10 (25.64)	29.6817
2010's	6 (15.38)	24.3611
2020's	1 (2.56)	2.80

Authors

Authors	Studies
Imai, S; Kashiwagi, H; Miyai, T; Momo, K; Sugawara, M; Takekuma, Y	1
Beumer, J; Bhatnagar, S; Haralam, M; Hoberman, A; Jeong, JH; Kearney, DH; Kurs-Lasky, M; Martin, JM; Miah, MK; Muñiz, G; Nagg, JP; Paradise, JL; Pope, MA; Rockette, HE; Shaikh, N; Shope, TR; Venkataramanan, R; Zhao, W	1
Huovinen, P; Jalava, J; Laine, MK; Lewnard, JA; Lindholm, L; Lipsitch, M; Ruohola, A; Tähtinen, PA	1
Laopaiboon, M; Thanaviratananich, S; Vatanasapt, P	2
Chu, CH; Ho, CY; Huang, CY; Liao, WH; Lin, LY; Shiao, AS; Tu, TY; Wang, MC	1
Naylor, JF	1
Laine, MK; Ruohola, A; Tähtinen, PA; Uitti, JM	1
Aguilar, L; Carcas, A; Cenjor, C; Garcia-Olmos, M; Gimenez, MJ; Parra, A; Ponte, C; Soriano, F	1
Greenberg, D; Leibovitz, E	1
Mokry, C	1
Bluestone, CD; Casselbrant, ML; Kurs-Lasky, M; Mandel, EM; Rockette, HE	1
Chonmaitree, T; Howie, V; Owen, M; Patel, JA; Reisner, B; Vizirinia, N	1
Aronoff, S; Arrieta, A; Aspin, MM; Hoberman, A; Lang, DJ; McCarty, J; McLinn, SE	1
Pichichero, ME	2
Bingen, E; Bourgeois, F; Lambert-Zechovsky, N	1
McCarty, JM; Phillips, A; Wiisanen, R	1
Blatter, MM; Bluestone, CD; Chan, KH; Fall, PA; Reisinger, KS; Tan, LS	1
Mason, EH; Mitchell, DK; Norris, DM; Pickering, LK; Van, R	1
del Castillo Martín, F	1
de la Flor i Brú, J	1
Esparcia Navarro, M; García Callejo, FJ; Orts Alborch, MH; Pardo Mateu, L; Velert Vila, MM	1
Boucherat, M; Cohen, R; de La Rocque, F; Langue, J; Levy, C	1
Deguchi, K; Fujimaki, Y; Harada, S; Kimura, S; Komatsu, N; Naito, M; Nomura, T; Okano, K; Senba, T; Shimizu, K; Sugita, R; Tanaka, M; Uchida, T; Watanabe, H; Yoshida, Y	1
Davis, P; Friedland, IR; Ghaffar, F; Katz, K; McCracken, GH; Muniz, LS; Reynolds, J; Smith, JL	1
Pichicero, M	1
François, M	1
Davis, P; Ghaffar, F; Katz, K; McCracken, GH; Muniz, LS; Shouse, T; Smith, JL	1
Hels, J	1
Lous, J	1
Cioce, C; Facchini, M; Pestalozza, G	1
Carlin, SA; Johnson, CE; Marchant, CD; Shurin, PA	1
Chomarat, M; Dubreuil, C	1
Denis, P; Gehanno, P; Gojon, D; Hoareau, J; Jacquet, P; Kosowski, A; Pascarel, J; Taillebe, M	1
Shurin, PA; Van Hare, GF	1
Carlin, SA; Feinstein, JC; Flexon, P; Fulton, D; Johnson, CE; Marchant, CD; Murdell-Panek, D; Shurin, PA; Van Hare, GF	1
Abid, A; Sehlane, M; Tazi-Lakhsassi, L	1

Reviews

9 review(s) available for clavulanic acid and Middle Ear Inflammation

Article	Year
Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media. The Cochrane database of systematic reviews, 2013, Dec-13, Issue:12 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Child; Clavulanic Acid; Drug Administration Schedule; Drug Therapy, Combination; Humans; Otitis Media; Randomized Controlled Trials as Topic	2013
Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media. The Cochrane database of systematic reviews, 2008, Oct-08, Issue:4 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Child; Clavulanic Acid; Drug Administration Schedule; Drug Therapy, Combination; Humans; Otitis Media; Randomized Controlled Trials as Topic	2008
Acute otitis media in children: current epidemiology, microbiology, clinical manifestations, and treatment. Chang Gung medical journal, 2004, Volume: 27, Issue:7 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Bacterial Vaccines; Cephalosporins; Child; Clavulanic Acid; Humans; Otitis Media; Quinolones; Streptococcus pneumoniae; Sulfonamides	2004
Assessing the treatment alternatives for acute otitis media. The Pediatric infectious disease journal, 1994, Volume: 13, Issue:1 Suppl 1 Topics: Acute Disease; Adolescent; Amoxicillin; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Humans; Infant; Otitis Media; Patient Compliance; Prescription Fees; Remission, Spontaneous	1994
[Clinical, diagnostic and therapeutic aspects of Moraxella catarrhalis infections]. Pathologie-biologie, 1993, Volume: 41, Issue:6 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Cell Membrane; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Diagnosis, Differential; Drug Resistance, Microbial; Humans; Infant; Infant, Newborn; Middle Aged; Moraxella catarrhalis; Neisseriaceae Infections; Otitis Media; Penicillinase; Respiratory Tract Infections; Virulence	1993
[Treatment of acute otitis media in children. Some questions]. Enfermedades infecciosas y microbiologia clinica, 1997, Volume: 15, Issue:4 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Humans; Incidence; Infant; Mastoiditis; Otitis Media	1997
[Antibiotic treatment of otitis media in children]. Atencion primaria, 1997, Sep-15, Volume: 20, Issue:4 Topics: Acute Disease; Age Factors; Amoxicillin; Anti-Bacterial Agents; Bacteria; Child; Clavulanic Acid; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Otitis Media; Penicillins	1997
Recurrent and persistent otitis media. The Pediatric infectious disease journal, 2000, Volume: 19, Issue:9 Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Child; Child, Preschool; Clavulanic Acid; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Infant, Newborn; Male; Otitis Media; Penicillins; Recurrence; Risk Factors; Streptococcal Infections; Streptococcus pneumoniae	2000
Short courses of antibiotic in acute otitis media and sinusitis infections. The Journal of international medical research, 2000, Volume: 28 Suppl 1 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Cefuroxime; Clavulanic Acid; Drug Administration Schedule; Drug Prescriptions; Drug Resistance, Microbial; Humans; Otitis Media; Sinusitis; Time Factors	2000

Trials

18 trial(s) available for clavulanic acid and Middle Ear Inflammation

Article	Year
Reduced-Concentration Clavulanate for Young Children with Acute Otitis Media. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:7 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Dermatitis; Diarrhea; Female; Humans; Infant; Infant, Newborn; Male; Otitis Media	2017
Impact of Antimicrobial Treatment for Acute Otitis Media on Carriage Dynamics of Penicillin-Susceptible and Penicillin-Nonsusceptible Streptococcus pneumoniae. The Journal of infectious diseases, 2018, 09-22, Volume: 218, Issue:9 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Double-Blind Method; Female; Humans; Infant; Male; Microbial Sensitivity Tests; Nasopharynx; Otitis Media; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae	2018
Close Follow-up in Children With Acute Otitis Media Initially Managed Without Antimicrobials. JAMA pediatrics, 2016, 11-01, Volume: 170, Issue:11 Topics: Acute Disease; Aftercare; Amoxicillin; Anti-Infective Agents; Child, Preschool; Clavulanic Acid; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Infant; Otitis Media; Placebos; Treatment Outcome; Tympanic Membrane Perforation; Watchful Waiting	2016
Efficacy of 20- versus 10-day antimicrobial treatment for acute otitis media. Pediatrics, 1995, Volume: 96, Issue:1 Pt 1 Topics: Acute Disease; Amoxicillin; beta-Lactamase Inhibitors; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Male; Otitis Media; Otitis Media with Effusion; Patient Compliance; Prognosis; Recurrence; Treatment Outcome	1995
Bacteriologic failure of amoxicillin-clavulanate in treatment of acute otitis media caused by nontypeable Haemophilus influenzae. The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 1 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Bacterial Typing Techniques; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Male; Microbial Sensitivity Tests; Moraxella catarrhalis; Neisseriaceae Infections; Otitis Media; Pneumococcal Infections; Prospective Studies; Treatment Failure	1995
Comparative study of the safety and efficacy of clarithromycin and amoxicillin-clavulanate in the treatment of acute otitis media in children. The Journal of pediatrics, 1994, Volume: 125, Issue:1 Topics: Acute Disease; Amoxicillin; beta-Lactamase Inhibitors; Child; Child, Preschool; Clarithromycin; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Ear, Middle; Female; Humans; Infant; Male; Otitis Media; Single-Blind Method; Treatment Outcome	1994
Comparative safety and efficacy of clarithromycin and amoxicillin/clavulanate in the treatment of acute otitis media in children. The Pediatric infectious disease journal, 1993, Volume: 12, Issue:12 Suppl 3 Topics: Acute Disease; Amoxicillin; beta-Lactamase Inhibitors; Child; Child, Preschool; Clarithromycin; Clavulanic Acid; Clavulanic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Male; Otitis Media; Single-Blind Method; Treatment Outcome	1993
Comparative study of sultamicillin and amoxicillin-clavulanate: treatment of acute otitis media. The Pediatric infectious disease journal, 1993, Volume: 12, Issue:1 Topics: Acute Disease; Amoxicillin; Ampicillin; beta-Lactamase Inhibitors; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infant; Male; Otitis Media; Sulbactam	1993
[Comparison of azithromycin, amoxicillin/clavulanic acid and cefaclor in the treatment of acute ENT infections]. Acta otorrinolaringologica espanola, 1998, Volume: 49, Issue:4 Topics: Acute Disease; Adult; Anti-Bacterial Agents; Azithromycin; Cefaclor; Cephalosporins; Clavulanic Acid; Female; Humans; Male; Maxillary Sinusitis; Otitis Media; Penicillins; Pharyngitis; Tonsillitis	1998
A multicenter, randomized, double-blind trial of 5 versus 10 days of antibiotic therapy for acute otitis media in young children. The Journal of pediatrics, 1998, Volume: 133, Issue:5 Topics: Acute Disease; Amoxicillin; Child, Preschool; Clavulanic Acid; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Infant; Male; Otitis Media; Prospective Studies	1998
[A clinicobacteriologic study on clavulanic acid/amoxicillin in pediatric acute otitis media]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:10 Topics: Acute Disease; Administration, Oral; Amoxicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Capsules; Child; Child, Preschool; Clavulanic Acid; Drug Combinations; Female; Haemophilus influenzae; Humans; Male; Moraxella catarrhalis; Nasopharynx; Otitis Media; Penicillin Resistance; Penicillins; Streptococcus pneumoniae	1999
Effects of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31, Issue:4 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Azithromycin; Carrier State; Child; Child, Preschool; Clavulanic Acid; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Male; Nasopharynx; Otitis Media; Pneumococcal Infections; Streptococcus pneumoniae	2000
Effects of large dosages of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, nonpneumococcal alpha-hemolytic streptococci, and Staphylococcus aureus in children with acute otitis media Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, May-15, Volume: 34, Issue:10 Topics: Acute Disease; Amoxicillin; Azithromycin; Bacterial Infections; Child, Preschool; Clavulanic Acid; Drug Therapy, Combination; Female; Haemophilus influenzae; Humans; Infant; Infant, Newborn; Male; Nasopharyngeal Diseases; Otitis Media; Serotyping; Staphylococcus aureus; Streptococcus; Streptococcus pneumoniae	2002
Azithromycin in upper respiratory tract infections: a clinical trial in children with otitis media. Scandinavian journal of infectious diseases. Supplementum, 1992, Volume: 83 Topics: Administration, Oral; Amoxicillin; Azithromycin; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Administration Schedule; Drug Therapy, Combination; Erythromycin; Female; Follow-Up Studies; Humans; Infant; Male; Otitis Media; Otitis Media with Effusion	1992
Measuring the comparative efficacy of antibacterial agents for acute otitis media: the "Pollyanna phenomenon". The Journal of pediatrics, 1992, Volume: 120, Issue:1 Topics: Acute Disease; Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefaclor; Cefixime; Cefotaxime; Clavulanic Acid; Clavulanic Acids; Double-Blind Method; Drug Combinations; Efficiency; Enzyme Inhibitors; Female; Haemophilus influenzae; Humans; Infant; Male; Moraxella catarrhalis; Otitis Media; Punctures; Streptococcus pneumoniae; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Tympanic Membrane	1992
[Treatment of acute otitis media: comparative study of efficacy of cefatrizine and amoxicillin-clavulanic acid]. Pathologie-biologie, 1991, Volume: 39, Issue:5 Topics: Acute Disease; Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Cefatrizine; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Otitis Media	1991
Short-course cefotaxime compared with five-day co-amoxyclav in acute otitis media in children. The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl A Topics: Acute Disease; Amoxicillin; Cefaclor; Cefotaxime; Ceftriaxone; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Female; Humans; Infant; Male; Otitis Media	1990
A randomized controlled trial of amoxicillin plus clavulanate compared with cefaclor for treatment of acute otitis media. The Journal of pediatrics, 1986, Volume: 109, Issue:5 Topics: Acute Disease; Amoxicillin; Cefaclor; Cephalexin; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Haemophilus influenzae; Humans; Infant; Male; Neisseria; Otitis Media; Otitis Media with Effusion; Random Allocation; Streptococcus pneumoniae	1986

Other Studies

12 other study(ies) available for clavulanic acid and Middle Ear Inflammation

Article	Year
Probiotic Prescription Status of Pediatric Patients with Otitis Media Receiving Oral Amoxicillin or Amoxicillin/Clavulanate from April 2016 to March 2017 Using a Japanese Health Insurance Claims Database. Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:3 Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Child; Child, Preschool; Clavulanic Acid; Databases, Factual; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Insurance, Health; Japan; Male; Otitis Media; Practice Patterns, Physicians'; Probiotics	2021
High-dose amoxicillin with clavulanate for the treatment of acute otitis media in children. TheScientificWorldJournal, 2013, Volume: 2013 Topics: Acute Disease; Amoxicillin; Child; Child, Preschool; Clavulanic Acid; Drug Therapy, Combination; Female; Humans; Male; Otitis Media; Retrospective Studies; Risk Factors; Seasons; Treatment Outcome	2013
Otoscope fogging: examination finding for perforated tympanic membrane. BMJ case reports, 2014, May-30, Volume: 2014 Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Humans; Male; Otitis Media; Otoscopes; Otoscopy; Tympanic Membrane Perforation; Tympanoplasty	2014
Does acetaminophen interfere in the antibiotic treatment of acute otitis media caused by a penicillin-resistant pneumococcus strain? A gerbil model. Pediatric research, 2003, Volume: 54, Issue:6 Topics: Acetaminophen; Acute Disease; Amoxicillin; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Clavulanic Acid; Disease Models, Animal; Drug Interactions; Erythromycin; Female; Gerbillinae; Otitis Media; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae	2003
Acute otitis media in children: amoxicillin remains the standard antibiotic, but justified in certain situations only. Prescrire international, 2003, Volume: 12, Issue:67 Topics: Amoxicillin; Ceftriaxone; Child; Clavulanic Acid; Clinical Trials as Topic; Drug Resistance, Bacterial; France; Haemophilus influenzae; Humans; Moraxella catarrhalis; Otitis Media; Penicillin V; Randomized Controlled Trials as Topic; Streptococcus pneumoniae	2003
Otitis media in children. The New England journal of medicine, 1995, Oct-26, Volume: 333, Issue:17 Topics: Amoxicillin; Anti-Bacterial Agents; Child; Clavulanic Acid; Clavulanic Acids; Drug Hypersensitivity; Humans; Otitis Media	1995
Prospective study of toxigenic Clostridium difficile in children given amoxicillin/clavulanate for otitis media. The Pediatric infectious disease journal, 1996, Volume: 15, Issue:6 Topics: Amoxicillin; Anti-Bacterial Agents; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Clostridioides difficile; Diarrhea; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Feces; Humans; Infant; Otitis Media; Penicillins; Prospective Studies; Toxins, Biological	1996
[Treatment of acute otitis media in children]. La Revue du praticien, 1998, Apr-15, Volume: 48, Issue:8 Topics: Acute Disease; Age Factors; Amoxicillin; Analgesics; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Cefpodoxime; Ceftizoxime; Cefuroxime; Cephalosporins; Child, Preschool; Clavulanic Acid; Conjunctivitis; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Otitis Media; Penicillins; Risk Factors	1998
[Otitis media and antibiotics 1]. Ugeskrift for laeger, 2002, Jun-03, Volume: 164, Issue:23 Topics: Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Drug Combinations; Drug Costs; Humans; Otitis Media; Penicillins	2002
[Otitis media and antibiotics 2]. Ugeskrift for laeger, 2002, Jun-03, Volume: 164, Issue:23 Topics: Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Drug Combinations; Humans; Otitis Media; Penicillins	2002
Therapy of acute otitis media caused by Branhamella catarrhalis. Preliminary report. Drugs, 1986, Volume: 31 Suppl 3 Topics: Amoxicillin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Neisseriaceae; Otitis Media; Penicillin Resistance; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1986
[Tolerance of amoxicillin-clavulanic acid combination in the child]. The Journal of international medical research, 1986, Volume: 14, Issue:3 Topics: Amoxicillin; Bacterial Infections; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Tolerance; Female; Humans; Male; Meningitis; Otitis Media; Pneumonia; Typhoid Fever; Urinary Tract Infections	1986