Page last updated: 2024-08-23

clavulanic acid and Acute Liver Injury, Drug-Induced

clavulanic acid has been researched along with Acute Liver Injury, Drug-Induced in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	15 (53.57)	18.2507
2000's	3 (10.71)	29.6817
2010's	9 (32.14)	24.3611
2020's	1 (3.57)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Abramson, K; Aithal, GP; Andrade, RJ; Bjornsson, ES; Chalasani, N; Cirulli, ET; Daly, AK; Fontana, RJ; Hallberg, P; Li, YJ; Long, N; Lucena, MI; Molokhia, M; Nelson, MR; Nicoletti, P; Odin, JA; Pirmohamed, M; Rafnar, T; Serrano, J; Stefánsson, K; Stolz, A; Watkins, PB	1
K V, S; Kanthlal, SK; Sasikumar, R; Simon, V	1
Leise, MD; Poterucha, JJ; Talwalkar, JA	1
Daly, AK; Faulkner, L; Jenkins, R; Kim, SH; Meng, X; Monshi, M; Naisbitt, DJ; Park, BK; Pirmohamed, M; Saide, K; Tailor, A; Wood, S; Yaseen, FS	1
Daly, AK; Farrell, J; Faulkner, L; Kim, SH; Naisbitt, DJ; Ogese, M; Park, BK; Pirmohamed, M; Saide, K; Tailor, A	1
Amelio, J; Ballarín, E; Ferrer, P; Ibáñez, L; Laporte, JR; Rottenkolber, M; Sabaté, M; Schmiedl, S; Vidal, X	1
Cho, JY; Chung, JY; Jang, IJ; Ji, SC; Kim, B; Kim, SH; Lee, J; Lee, SH; Lim, KS; Park, HS; Shin, KH; Yi, S; Yoon, SH; Yu, KS	1
Agúndez, JA; Andrade, RJ; Anzola, S; Borraz, Y; Castiella, A; Costa, J; Fernández, MC; García-Martín, E; Lucena, MI; Martínez, C; Planas, R; Romero-Gomez, M; Ulzurrun, E	1
Cattelan, AM; Mencarelli, R; Meneghetti, F; Trevenzoli, M	1
Buenestado, J; Galindo, C; Piñol, MC; Reñé, JM	1
Butruk, E; Habior, A; Walewska-Zielecka, B	1
Geubel, AP; Horsmans, Y	1
Carreira, J; del Olmo, ME; Palacios, ML; Panadero, E; Panadero, FJ	1
García Rodríguez, LA; Stricker, BH; Zimmerman, HJ	1
Kurowski, V	1
Hammond, L; Hewitt, J	1
Caballero Plasencia, AM; Guilarte López-Mañas, J; Martín Ruiz, JL; Valenzuela Barranco, M	1
Bralet, MP; Zafrani, ES	1
Berenguer Lapuerta, J; Bustamante Balén, M; García Herola, A; Pérez Aguilar, F; Rayón Martín, M	1
Arenas, JI; Barrio, J; Castiella, A; Cosme, A; García-Bengoechea, M; Indart, A; Lobo, C; López, P	1
Brenard, R; Demanet, C; Geubel, AP; Hautekeete, ML; Henrion, J; Horsmans, Y; Michielsen, PP; Rahier, J; Sempoux, C; Van Waeyenberge, C; Verbist, L; Yap, PS	1
Elmalem, E	1
Beauchant, M; Fort, E; Labat-Labourdette, J; Levillain, P; Silvain, C	1
Rodrigo, L; Rodríguez, M; Sleiman, H; Suárez, A	1
Alves, T; Cleau, D; Floriot, C; Gury, S; Jobard, JM; Noirot, A; Rey, B; Vieille, J; Vuillemard, M; Wagschal, G	1

Reviews

5 review(s) available for clavulanic acid and Acute Liver Injury, Drug-Induced

Article	Year
Drug-induced liver injury. Mayo Clinic proceedings, 2014, Volume: 89, Issue:1 Topics: Adult; Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Causality; Chemical and Drug Induced Liver Injury; China; Clavulanic Acid; Comorbidity; Democratic People's Republic of Korea; Dietary Supplements; Enzyme Inhibitors; Female; Fluoroquinolones; France; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iceland; Isoniazid; Liver Diseases; Male; Protein-Tyrosine Kinases; Republic of Korea; Spain; Tumor Necrosis Factor-alpha; United States	2014
Systematic Review and Meta-Analysis: Macrolides- and Amoxicillin/Clavulanate-induced Acute Liver Injury. Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:1 Topics: Amoxicillin; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Macrolides; Randomized Controlled Trials as Topic	2016
[Acute pancreatitis associated with hepatotoxicity induced by amoxicillin-clavulanic acid]. Revista espanola de enfermedades digestivas, 1995, Volume: 87, Issue:8 Topics: Acute Disease; Adult; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Humans; Male; Pancreatitis; Penicillins	1995
[Cholestatic hepatitis caused by amoxycillin-clavulanic acid. Report of a new case]. Gastroenterologia y hepatologia, 1997, Volume: 20, Issue:4 Topics: Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clavulanic Acids; Humans; Male; Middle Aged; Penicillins	1997
[Cholestatic hepatitis induced by the amoxicillin-clavulanic acid combination. A case and review of the literature]. Gastroenterologie clinique et biologique, 1990, Volume: 14, Issue:12 Topics: Amoxicillin; Chemical and Drug Induced Liver Injury; Cholestasis; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Humans; Male; Middle Aged	1990

Trials

1 trial(s) available for clavulanic acid and Acute Liver Injury, Drug-Induced

Article	Year
Exploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches. Clinical and translational science, 2017, Volume: 10, Issue:3 Topics: Adult; Alanine Transaminase; Amoxicillin; Biomarkers; Cell Proliferation; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Demography; Humans; Lymphocytes; Male; Metabolome; MicroRNAs; Time Factors	2017

Other Studies

22 other study(ies) available for clavulanic acid and Acute Liver Injury, Drug-Induced

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury. Gastroenterology, 2019, Volume: 156, Issue:6 Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Black or African American; Case-Control Studies; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Female; Gene Frequency; Genome-Wide Association Study; Hispanic or Latino; HLA-A2 Antigen; HLA-DRB1 Chains; Humans; Male; Middle Aged; Mutation, Missense; Polymorphism, Single Nucleotide; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Risk Factors; White People	2019
In Vitro Protective Effect of Ascorbic Acid Against Antibiotic-Induced Hepatotoxicity. Current drug discovery technologies, 2020, Volume: 17, Issue:3 Topics: Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cell Survival; Chemical and Drug Induced Liver Injury; Chickens; Clavulanic Acid; Disease Models, Animal; Drug Evaluation, Preclinical; Hepatocytes; Humans; Lipid Peroxidation; Liver; Mice; Oxidative Stress; Primary Cell Culture; Sulfamethoxazole; Tetracycline	2020
Promiscuous T-cell responses to drugs and drug-haptens. The Journal of allergy and clinical immunology, 2015, Volume: 136, Issue:2 Topics: Amoxicillin; Anti-Bacterial Agents; Antigen-Presenting Cells; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clone Cells; Floxacillin; Gene Expression; Haptens; HLA Antigens; Humans; Lymphocyte Activation	2015
Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury. Hepatology (Baltimore, Md.), 2015, Volume: 62, Issue:3 Topics: Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Case-Control Studies; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clone Cells; Female; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Reference Values; Sampling Studies	2015
Glutathione S-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury. Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Female; Gene Deletion; Genetic Predisposition to Disease; Genotype; Glutathione Transferase; Heterozygote; Humans; Liver Diseases; Male; Middle Aged; Polymorphism, Genetic; Sex Factors	2008
Severe hepatitis associated with oxacillin therapy. Southern medical journal, 2003, Volume: 96, Issue:3 Topics: Adult; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Drug Therapy, Combination; Female; Humans; Oxacillin; Penicillins	2003
Hepatocellular-cholestatic liver injury due to amoxycillin-clavulanic acid combination. The Clinical investigator, 1994, Volume: 72, Issue:8 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Therapy, Combination; Female; Granuloma; Humans; Male; Middle Aged; Respiratory Tract Infections; Tonsillitis	1994
Amoxycillin-clavulanic acid-erythromycin cross-liver toxicity: a case report. Journal of hepatology, 1994, Volume: 21, Issue:5 Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clavulanic Acids; Erythromycin; Humans; Liver; Male	1994
[Hepatitis caused by amoxicillin plus clavulanic acid]. Atencion primaria, 1994, Jun-15, Volume: 14, Issue:1 Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Female; Humans	1994
Risk of acute liver injury associated with the combination of amoxicillin and clavulanic acid. Archives of internal medicine, 1996, Jun-24, Volume: 156, Issue:12 Topics: Acute Disease; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Child; Clavulanic Acid; Clavulanic Acids; Cohort Studies; Databases, Factual; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Penicillins; Retrospective Studies; Risk; United Kingdom	1996
[Cholestatic jaundice induced by amoxicillin and clavulanic acid]. Deutsche medizinische Wochenschrift (1946), 1996, Mar-22, Volume: 121, Issue:12 Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cholestasis; Cholestasis, Intrahepatic; Clavulanic Acid; Clavulanic Acids; Humans; Male; Penicillins	1996
Adverse hepatic events associated with drug therapy. The Medical journal of Australia, 1996, Sep-16, Volume: 165, Issue:6 Topics: Adverse Drug Reaction Reporting Systems; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Floxacillin; Humans; Penicillins	1996
[Hepatotoxicity caused by amoxicillin, clavulanic acid or both?]. Gastroenterologia y hepatologia, 1997, Volume: 20, Issue:1 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Biopsy; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Clinical Enzyme Tests; Drug Therapy, Combination; Female; Humans; Liver; Male; Middle Aged; Penicillins; Time Factors	1997
[Hepatitis caused by the amoxicillin-clavulanic acid combination. An example of drug-induced biliary hepatotoxicity]. Annales de pathologie, 1996, Volume: 16, Issue:6 Topics: Amoxicillin; beta-Lactamase Inhibitors; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Penicillins	1996
[Cholestatic acute hepatitis induced by amoxycillin-clavulanic acid combination. Role of ursodeoxycholic acid in drug-induced cholestasis]. Revista espanola de enfermedades digestivas, 1998, Volume: 90, Issue:7 Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Clavulanic Acid; Humans; Male; Penicillins; Ursodeoxycholic Acid	1998
HLA association of amoxicillin-clavulanate--induced hepatitis. Gastroenterology, 1999, Volume: 117, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Female; Haplotypes; Histocompatibility Antigens Class II; HLA-DQ Antigens; HLA-DQ beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; HLA-DRB5 Chains; Humans; Male; Middle Aged	1999
Nimesulide, clavulanic acid and hepatitis. Journal of internal medicine, 2000, Volume: 248, Issue:2 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Humans; Liver; Liver Failure; Sulfonamides	2000
Granulomatous hepatitis due to combination of amoxicillin and clavulanic acid. Digestive diseases and sciences, 1992, Volume: 37, Issue:1 Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Biopsy; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Granuloma; Humans; Liver; Liver Diseases; Male	1992
[Cholestatic hepatitis caused by amoxicillin-clavulanic acid]. Medicina clinica, 1991, Jan-19, Volume: 96, Issue:2 Topics: Aged; Aged, 80 and over; Amoxicillin; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Humans; Male	1991