clavosolide-a and Ovarian-Neoplasms

clavosolide-a has been researched along with Ovarian-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for clavosolide-a and Ovarian-Neoplasms

Article	Year
New dimeric macrolide glycosides from the marine sponge Myriastra clavosa. Journal of natural products, 2002, Volume: 65, Issue:9 Clavosolides A-D (1-4), dimeric macrolides incorporating cyclopropyl, tetrahydropyranyl, and glycosidic ring systems, were isolated from the cytotoxic extract of a Philippines collection of the marine sponge Myriastra clavosa. The structures of the clavosolides, which occurred as only trace metabolites, were elucidated through extensive NMR spectroscopic analyses. Clavosolides A (1) and B (2) were recently reported metabolites from M. clavosa, while the unsymmetrical dimers clavosolides C (3) and D (4) had new structures. Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Macrolides; Melanoma; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Philippines; Porifera; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Tumor Cells, Cultured	2002

Article

Year

New dimeric macrolide glycosides from the marine sponge Myriastra clavosa.

Journal of natural products, 2002, Volume: 65, Issue:9

Clavosolides A-D (1-4), dimeric macrolides incorporating cyclopropyl, tetrahydropyranyl, and glycosidic ring systems, were isolated from the cytotoxic extract of a Philippines collection of the marine sponge Myriastra clavosa. The structures of the clavosolides, which occurred as only trace metabolites, were elucidated through extensive NMR spectroscopic analyses. Clavosolides A (1) and B (2) were recently reported metabolites from M. clavosa, while the unsymmetrical dimers clavosolides C (3) and D (4) had new structures.

Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Macrolides; Melanoma; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Philippines; Porifera; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Tumor Cells, Cultured

2002