cladribine has been researched along with Germinoblastoma in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.68) | 18.7374 |
| 1990's | 19 (61.29) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blicharski, K; Borowicz, P; Janota, B; Kłaput, U; Mazur, L; Opydo-Chanek, M; Stojak, M; Wojcieszek, K | 1 |
| Andersson, BS; Champlin, RE; Ji, J; Li, Y; Liu, Y; Nieto, Y; Teo, EC; Valdez, BC | 1 |
| Moutsopoulos, HM; Petroutsos, G; Skopouli, FN; Voulgarelis, M | 1 |
| Boehrer, S; Chow, KU; Hoelzer, D; Knau, A; Mitrou, PS; Nowak, D; Ruthardt, M; Weidmann, E | 1 |
| Balzarini, J; Bontemps, F; Delacauw, A; Galmarini, C; Meier, C; van den Neste, E | 1 |
| Csoka, K; Larsson, R; Liliemark, J; Nygren, P | 1 |
| Duley, J; Fabianowska-Majewska, K; Simmonds, A; Tybor, K | 1 |
| Bryson, HM; Sorkin, EM | 1 |
| Piro, LD; Saven, A | 4 |
| Beutler, E | 2 |
| Saven, A | 1 |
| Betticher, DC; Fey, MF; Gratwohl, A; Hess, U; Jenzer, H; Lohri, A; Pagani, O; Pugin, P; Tobler, A; von Rohr, A | 1 |
| Castaigne, S | 1 |
| Wiley, JS | 1 |
| Betticher, DC; Cabrol, C; Laurencet, FM; Zulian, GB | 1 |
| Cheson, BD | 2 |
| Chojnowski, K; Góra-Tybor, J; Robak, T | 1 |
| Juneja, SK; Westerman, DA | 1 |
| Cabanillas, F | 1 |
| Itälä, M; Remes, K | 1 |
| Piro, LD | 1 |
| Grieb, P; Robak, T | 1 |
| Robak, T | 1 |
| Carrera, CJ; Carson, DA; Lotz, M; Piro, LD; Yamanaka, H | 1 |
| Hiramoto-Yoshioka, A; Hirota, Y; Matsuda, A; Minowada, J; Otani, T; Tanaka, S; Ueda, T; Wataya, Y | 1 |
| Carrera, CJ; Carson, DA; Wasson, DB; Yamanaka, H | 1 |
13 review(s) available for cladribine and Germinoblastoma
| Article | Year |
|---|---|
Cladribine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in haematological malignancies.
Topics: Animals; Cladribine; Hematologic Diseases; Humans; In Vitro Techniques; Leukemia; Lymphoma | 1993 |
The newer purine analogs. Significant therapeutic advance in the management of lymphoid malignancies.
Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia; Lymphoma; Pentostatin; Vidarabine | 1993 |
New chemotherapeutic agent: 2-chlorodeoxyadenosine.
Topics: Cladribine; Humans; Leukemia; Lymphoma | 1994 |
2-Chlorodeoxyadenosine: a newer purine analog active in the treatment of indolent lymphoid malignancies.
Topics: Animals; Cladribine; Humans; Leukemia; Lymphoma | 1994 |
Comparative efficacy of the newer nucleosides (fludarabine, 2'-deoxycoformycin, and 2-chlorodeoxyadenosine) in the treatment of indolent lymphoid malignancies.
Topics: Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Humans; Leukemia; Lymphoma; Molecular Structure; Pentostatin; Purine Nucleosides; Vidarabine | 1993 |
2-Chlorodeoxyadenosine: a new nucleoside agent effective in the treatment of lymphoid malignancies.
Topics: Cladribine; Humans; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous | 1993 |
2-Chlorodeoxyadenosine in haematological malignancies.
Topics: Cladribine; Humans; Leukemia; Lymphoma | 1993 |
2-Chlorodeoxyadenosine treatment of lymphoma.
Topics: Adenosine Deaminase; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cladribine; Humans; Lymphoma; Lymphoma, B-Cell; Lymphoma, T-Cell, Cutaneous; Pentostatin; Vidarabine; Waldenstrom Macroglobulinemia | 1996 |
Purine nucleoside analogs in indolent non-Hodgkin's lymphoma.
Topics: Adenosine Deaminase Inhibitors; Antibiotics, Antineoplastic; Cladribine; Humans; Lymphoma; Pentostatin; Vidarabine Phosphate | 2000 |
[Nucleoside analogues--new drugs for the treatment of lymphatic cancers].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Humans; Leukemia, Lymphoid; Lymphoma; Nucleosides; Pentostatin; Vidarabine | 2001 |
Cladribine (2-chlorodeoxyadenosine)
Topics: Cladribine; Humans; Leukemia; Leukemia, Hairy Cell; Lymphoma | 1992 |
New antimetabolites in the treatment of human malignancies.
Topics: Animals; Antimetabolites, Antineoplastic; Cladribine; Clinical Trials as Topic; Drugs, Investigational; Forecasting; Humans; Immunosuppression Therapy; Leukemia; Lymphoma; Pentostatin; Purines; Vidarabine | 1992 |
[New analogs of deoxyadenosine for treatment of lymphoid malignancies].
Topics: Antineoplastic Agents; Cladribine; Deoxyadenosines; Formycins; Humans; Leukemia; Lymphoma; Vidarabine | 1992 |
2 trial(s) available for cladribine and Germinoblastoma
| Article | Year |
|---|---|
2-chloro-2'-deoxyadenosine in the treatment of Sjögren's syndrome-associated B cell lymphoproliferation.
Topics: Adult; Antineoplastic Agents; B-Lymphocytes; Cladribine; Female; Humans; Infusions, Intravenous; Lymphoma; Male; Middle Aged; Sjogren's Syndrome; Treatment Outcome | 2002 |
High incidence of infections after 2-chlorodeoxyadenosine (2-CDA) therapy in patients with malignant lymphomas and chronic and acute leukaemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Bone Marrow Diseases; Chronic Disease; Cladribine; Female; Humans; Immunocompromised Host; Incidence; Leukemia; Lymphoma; Male; Middle Aged; Opportunistic Infections; Prospective Studies; Treatment Outcome | 1994 |
16 other study(ies) available for cladribine and Germinoblastoma
| Article | Year |
|---|---|
In vitro response of human pathological hematopoietic cells to cladribine.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cladribine; Dose-Response Relationship, Drug; Humans; Leukemia; Lymphoma | 2013 |
Cladribine, gemcitabine, busulfan, and SAHA combination as a potential pretransplant conditioning regimen for lymphomas: A preclinical study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Busulfan; Cell Line, Tumor; Cell Membrane Permeability; Cladribine; Deoxycytidine; DNA Damage; Drug Synergism; Gemcitabine; Hematopoietic Stem Cell Transplantation; Histones; Humans; Hydroxamic Acids; Intracellular Membranes; Lymphoma; Mitochondria; Signal Transduction; Transplantation Conditioning; Vorinostat | 2016 |
Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase activation
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Bendamustine Hydrochloride; Carrier Proteins; Caspases; Cladribine; Co-Repressor Proteins; Cytochrome c Group; Cytoskeletal Proteins; Down-Regulation; Doxorubicin; Drug Synergism; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Lymphoma; Mitochondrial Proteins; Mitoxantrone; Molecular Chaperones; Nitrogen Mustard Compounds; Nuclear Proteins; Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein | 2003 |
Study of the efficacy of a pronucleotide of 2-chloro-2'-deoxyadenosine in deoxycytidine kinase-deficient lymphoma cells.
Topics: Cell Line, Tumor; Cell Survival; Cladribine; Cyclic AMP; Deoxycytidine Kinase; Diffusion; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Hydrolysis; Lymphoma; Models, Chemical; Nucleotides; Phosphorylation | 2006 |
Evaluation of the cytotoxic activity of gemcitabine in primary cultures of tumor cells from patients with hematologic or solid tumors.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Cladribine; Colorectal Neoplasms; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; In Vitro Techniques; Leukemia; Lung Neoplasms; Lymphoma; Ribonucleotide Reductases; Tumor Cells, Cultured; Urogenital Neoplasms | 1995 |
The influence of 2-chloro-2'-deoxyadenosine on metabolism of deoxyadenosine in human primary CNS lymphoma.
Topics: 5'-Nucleotidase; Adenine Phosphoribosyltransferase; Adenosine Deaminase; Adenosine Monophosphate; Adenosylhomocysteinase; Apoptosis; Central Nervous System Neoplasms; Cladribine; Deamination; Deoxyadenosines; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrolases; Lymphoma; Phosphorylation | 1995 |
Seeking the nucleoside transporter.
Topics: Animals; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Membrane; Cladribine; Cloning, Molecular; Cytarabine; Deoxycytidine; Erythrocytes; Gemcitabine; Glucose Transporter Type 1; Humans; Leukemia; Lymphoma; Membrane Proteins; Monosaccharide Transport Proteins; Nucleosides; Oocytes; Recombinant Proteins; Uridine; Vidarabine; Xenopus | 1997 |
Myelodysplastic syndrome with biclonal monosomy 7 and trisomy 8 after treatment with cladribine (2-chloro-2-deoxyadenosine) and involved field radiation therapy.
Topics: Adult; Antineoplastic Agents; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Cladribine; Humans; Lymphoma; Male; Myelodysplastic Syndromes; Trisomy | 1997 |
New prospects in the treatment of indolent lymphomas with purine analogues.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Pentostatin; Vidarabine | 1998 |
Cladribine as monotherapy or combined with dexamethasone and idarubicin or mitoxantrone in previously treated patients with low-grade lymphoid malignancies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Dexamethasone; Female; Humans; Idarubicin; Lymphoma; Male; Middle Aged; Mitoxantrone | 2000 |
Test and teach. Number one hundred and one: Part 1.
Topics: Aged; Antigens, CD; Antineoplastic Agents; Bone Marrow Cells; Cladribine; Diagnosis, Differential; Humans; Immunophenotyping; Immunosuppressive Agents; Leukemia, Hairy Cell; Leukemic Infiltration; Lymphoma; Male; Splenectomy; Splenic Neoplasms; Treatment Outcome | 2000 |
2-Chlorodeoxyadenosine treatment of lymphoid malignancies.
Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Deoxyadenosines; Humans; Leukemia; Lymphoma | 1992 |
[2-chlorodeoxyadenosine (2-CDA)--a new antineoplastic and immunosuppressive drug].
Topics: Adult; Animals; Autoimmune Diseases; Child; Cladribine; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Immunosuppressive Agents; Leukemia; Leukemia, Experimental; Lymphoma; Mice | 1992 |
Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo.
Topics: 2-Chloroadenosine; Cladribine; Deoxyadenosines; DNA Damage; Humans; In Vitro Techniques; Lymphoma; Monocytes; Pentostatin; T-Lymphocytes | 1989 |
The mechanism of 2-chlorodeoxyadenosine-induced cell death.
Topics: 2-Chloroadenosine; Cell Survival; Cladribine; Cycloheximide; Deoxyadenosines; Deoxycytidine; DNA Damage; Humans; Leukemia; Lymphoma; Tumor Cells, Cultured | 1989 |
Programmed cell death and adenine deoxynucleotide metabolism in human lymphocytes.
Topics: Cell Survival; Cladribine; Deoxyadenosines; DNA Damage; Humans; Leukemia; Lymphocytes; Lymphoma; NAD | 1988 |