Page last updated: 2024-08-22

cladribine and Benign Neoplasms

cladribine has been researched along with Benign Neoplasms in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's8 (38.10)18.2507
2000's6 (28.57)29.6817
2010's5 (23.81)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Allen-Philbey, K; Baker, D; De Trane, S; Giovannoni, G; Mateo-Casas, M; Mathews, J; O'Toole, EA; Reyes, S; Schmierer, K; Yildiz, O1
Cros-Perrial, E; Dumontet, C; Jordheim, LP; Lefebvre-Tournier, I; Peyrottes, S; Puy, JY1
Holmøy, T; Myhr, KM; Torkildsen, Ø1
Rommer, PS; Zettl, UK1
Bagley, RG; Crawford, J; Krumbholz, R; Kurtzberg, LS; Lovett, D; Roth, S; Rouleau, C; Schmid, S; Teicher, BA; Yao, M1
Epner, EM; Phillips, JD; Spurgeon, S; Yu, M1
Schmidt, S1
Comi, G; Cook, S; Giovannoni, G; Greenberg, SJ; Hamlett, A; Miret, M; Musch, B; Rammohan, K; Rieckmann, P; Sørensen, PS; Vermersch, P; Viglietta, V; Weiner, J1
Józefowicz-Okonkwo, G; Robak, T; Szmigielska-Kapłon, A1
Hamaki, T; Heike, Y; Hori, A; Kami, M; Kim, SW; Kishi, Y; Kojima, R; Kusumi, E; Masuo, S; Miyakoshi, S; Mori, S; Morinaga, S; Murashige, N; Muto, Y; Takaue, Y; Taniguchi, S; Tanosaki, R; Ueyama, J; Yuji, K1
Gojkovic, Z; Hasholt, L; Joergensen, T; Knecht, W; Le Breton, C; Munch-Petersen, B; Piskur, J; Rozpedowska, E; Sandrini, MP; Willer, M1
Burris, HA; Eckardt, JR; Fields, S; Kuhn, JG; Rizzo, J; Rodriguez, GI; Smith, LS; VanDenBerg, K; von Hoff, DD; Weiss, GR1
Kobayashi, K; O'Brien, SM; Ratain, MJ; Schilsky, RL; Vogelzang, NJ; Vokes, EE1
Arnér, E; Brosjö, O; Eriksson, S; Gunvén, P; Julusson, G; Karlsson, A; Liliemark, J; Spasokoukotskaja, T; Wang, L1
Csoka, K; de la Torre, M; Fridborg, H; Kristensen, J; Larsson, R; Liliemark, J; Nygren, P1
Beutler, E; Carrera, CJ; Carson, DA; Copeland, B; Kawasaki, H; Kosty, M; Piro, LD; Saven, A; Waltz, T; Zyroff, J1
Block, T; Depenbrock, H; Fellbaum, C; Hanauske, AR; Peter, R; Rastetter, J; Wenger, M1
Cheung, WK; Gollard, R; Johannsen, T; Kosty, M; Miller, WE; Moyer, M; Piro, LD; Rose, E; Saven, A; Smith, I1
Delannoy, A; Feremans, W; Ferrant, A; Michaux, L; Van Den Neste, E1
Cheson, BD1
Hutton, JJ; Von Hoff, DD1

Reviews

6 review(s) available for cladribine and Benign Neoplasms

ArticleYear
An update on cladribine for relapsing-remitting multiple sclerosis.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:15

    Topics: Administration, Oral; Cladribine; Humans; Immunosuppressive Agents; Multiple Sclerosis, Relapsing-Remitting; Neoplasms; Randomized Controlled Trials as Topic; Treatment Outcome

2017
Managing the side effects of multiple sclerosis therapy: pharmacotherapy options for patients.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:5

    Topics: Alemtuzumab; Cladribine; Crotonates; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Hydroxybutyrates; Immunologic Factors; Immunosuppressive Agents; Interferon-beta; Multiple Sclerosis; Natalizumab; Neoplasms; Nitriles; Toluidines

2018
Cladribine: not just another purine analogue?
    Expert opinion on investigational drugs, 2009, Volume: 18, Issue:8

    Topics: Adenosine Deaminase Inhibitors; Antineoplastic Agents; Autoimmune Diseases; Cladribine; Clinical Trials as Topic; DNA Methylation; Humans; Molecular Structure; Neoplasms; Purines

2009
[Oral cladribine for relapsing-remitting multiple sclerosis: another purine analogue or a genuine therapeutic innovation?].
    Der Nervenarzt, 2010, Volume: 81, Issue:10

    Topics: Administration, Oral; Adverse Drug Reaction Reporting Systems; Animals; Azathioprine; Cladribine; Clinical Trials, Phase III as Topic; Disability Evaluation; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Infusions, Intravenous; Long-Term Care; Lymphopenia; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Neoplasms; Pregnancy; Purine Nucleosides; Randomized Controlled Trials as Topic; Thrombocytopenia

2010
Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy.
    Advances in enzyme regulation, 1994, Volume: 34

    Topics: Adenocarcinoma; Burkitt Lymphoma; Cells, Cultured; Cladribine; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Hairy Cell; Leukocytes, Mononuclear; Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Sarcoma

1994
Second primary tumors and immune phenomena after fludarabine or 2-chloro-2'-deoxyadenosine treatment.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:5-6

    Topics: Antineoplastic Agents; Autoimmunity; Cladribine; Humans; Immunosuppressive Agents; Neoplasms; Neoplasms, Second Primary; Vidarabine

2001

Trials

3 trial(s) available for cladribine and Benign Neoplasms

ArticleYear
Safety and tolerability of cladribine tablets in multiple sclerosis: the CLARITY (CLAdRIbine Tablets treating multiple sclerosis orallY) study.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2011, Volume: 17, Issue:5

    Topics: Administration, Oral; Adult; Cladribine; Disability Evaluation; Double-Blind Method; Europe; Herpes Zoster; Humans; Immunosuppressive Agents; Lymphopenia; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neoplasms; Neurologic Examination; Physical Examination; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; United States; Young Adult

2011
A phase I and pharmacokinetics study of 2-chlorodeoxyadenosine in patients with solid tumors.
    Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:5

    Topics: Adult; Aged; Agranulocytosis; Anemia; Cell Count; Chromatography, High Pressure Liquid; Cladribine; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Lymphopenia; Male; Middle Aged; Neoplasms; Neutrophils; Thrombocytopenia

1995
A phase I study of intermittent infusion cladribine in patients with solid tumors.
    Cancer, 1994, Jul-01, Volume: 74, Issue:1

    Topics: Adult; Aged; Blindness; Carcinoma, Non-Small-Cell Lung; Cladribine; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Neutropenia; Thrombocytopenia

1994

Other Studies

12 other study(ies) available for cladribine and Benign Neoplasms

ArticleYear
Severe skin reactions associated with cladribine in people with multiple sclerosis.
    Multiple sclerosis and related disorders, 2020, Volume: 43

    Topics: Cladribine; Humans; Immunosuppressive Agents; Multiple Sclerosis; Neoplasms; Recurrence

2020
Determination and quantification of intracellular fludarabine triphosphate, cladribine triphosphate and clofarabine triphosphate by LC-MS/MS in human cancer cells.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, May-15, Volume: 1053

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Antineoplastic Agents; Arabinonucleosides; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cladribine; Clofarabine; Humans; Limit of Detection; Neoplasms; Polyphosphates; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Vidarabine

2017
Bone marrow CFU-GM and human tumor xenograft efficacy of three antitumor nucleoside analogs.
    International journal of oncology, 2009, Volume: 34, Issue:5

    Topics: Adenine Nucleotides; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Bone Marrow Cells; Cells, Cultured; Cladribine; Clofarabine; Granulocyte-Macrophage Progenitor Cells; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Models, Biological; Neoplasms; Treatment Outcome; Vidarabine Phosphate; Xenograft Model Antitumor Assays

2009
Cytotoxic effect of cyclosporin A alone and in combination with 2-chlorodeoxyadenosine against P388 murine leukemia in vivo.
    Medical science monitor : international medical journal of experimental and clinical research, 2002, Volume: 8, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclosporine; Drug Synergism; Immunosuppressive Agents; Male; Mice; Neoplasm Transplantation; Neoplasms; Purines; Time Factors; Tumor Cells, Cultured

2002
Feasibility of reduced intensity hematopoietic stem cell transplantation from an HLA-matched unrelated donor.
    Bone marrow transplantation, 2004, Volume: 33, Issue:7

    Topics: Adult; Aged; Antilymphocyte Serum; Bone Marrow Transplantation; Cladribine; Feasibility Studies; Female; Graft vs Host Disease; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Histocompatibility; Histocompatibility Testing; Humans; Male; Middle Aged; Neoplasms; Retrospective Studies; Survival Analysis; Transplantation Conditioning; Transplantation Immunology; Treatment Outcome; Vidarabine; Whole-Body Irradiation

2004
Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs.
    Gene therapy, 2007, Volume: 14, Issue:17

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Cell Line, Tumor; Cladribine; Cytarabine; Directed Molecular Evolution; Drosophila melanogaster; Genes, Transgenic, Suicide; Genetic Therapy; Glioblastoma; Humans; Lethal Dose 50; Mutation; Neoplasms; Osteosarcoma; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Purines; Substrate Specificity; Transduction, Genetic; Vidarabine

2007
In vitro activity of 2-chlorodeoxyadenosine (CdA) in primary cultures of human haematological and solid tumours.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:7

    Topics: Adrenocortical Carcinoma; Breast Neoplasms; Cladribine; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lung Neoplasms; Neoplasms; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

1994
2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:4

    Topics: Adult; Aged; Astrocytoma; Bone Marrow; Brain Neoplasms; Carcinoma, Renal Cell; Cladribine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasms; Nervous System

1993
Investigation of the comparative effects of 2-chlorodeoxyadenosine on tumor colony forming units in vitro.
    Investigational new drugs, 1995, Volume: 13, Issue:2

    Topics: Antineoplastic Agents; Cell Division; Cisplatin; Cladribine; Dose-Response Relationship, Drug; Doxorubicin; Drugs, Investigational; Etoposide; Fluorouracil; Humans; Mitomycin; Neoplasms; Neoplastic Stem Cells; Tumor Stem Cell Assay; Vinblastine

1995
Pharmacokinetic study of oral and bolus intravenous 2-chlorodeoxyadenosine in patients with malignancy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Biological Availability; Cladribine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia; Male; Middle Aged; Neoplasms; Neutropenia; Treatment Outcome

1996
Clinical trials referral resource. Clinical trials with 2-chlorodeoxyadenosine.
    Oncology (Williston Park, N.Y.), 1992, Volume: 6, Issue:5

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Humans; Leukemia, Hairy Cell; Neoplasms

1992
Cytotoxicity of 2-chlorodeoxyadenosine in a human tumor colony-forming assay.
    Cancer drug delivery, 1986,Spring, Volume: 3, Issue:2

    Topics: Cell Survival; Cells, Cultured; Cladribine; Colony-Forming Units Assay; Deoxyadenosines; Drug Evaluation, Preclinical; Female; Humans; Kinetics; Neoplasms; Vidarabine

1986