Page last updated: 2024-08-22

cladribine and B-Cell Chronic Lymphocytic Leukemia

cladribine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 218 studies

Research

Studies (218)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.46)18.7374
1990's109 (50.00)18.2507
2000's76 (34.86)29.6817
2010's30 (13.76)24.3611
2020's2 (0.92)2.80

Authors

AuthorsStudies
Korycka-Wołowiec, AB; Kubiak, AB; Robak, T; Wołowiec, D; Ziółkowska, EI1
Ahn, IE; Calvo, KR; Francischetti, IMB; Kreitman, RJ; Obiorah, IE; Raffeld, M; Wang, HW; Wang, W; Wiestner, A1
Gaherova, L; Havrda, M; Kozak, T; Novak, J; Spicka, J1
Bołkun, Ł; Budziszewska, BK; Błoński, J; Fidecka, M; Kłoczko, J; Piotrowska, M; Robak, T; Rybka, J; Skotnicki, AB; Smolewski, P; Uss, A; Walczak, U; Wróbel, T1
Bogusz, J; Cebula-Obrzut, B; Majchrzak, A; Mędra, A; Robak, T; Smolewski, P1
Blonski, JZ; Calbecka, M; Ceglarek, B; Chojnowski, K; Dmoszynska, A; Dwilewicz-Trojaczek, J; Gora-Tybor, J; Hellmann, A; Kloczko, J; Kostyra, A; Kowal, M; Kuliczkowski, K; Lewandowski, K; Mital, A; Nowak, W; Potoczek, S; Robak, T; Seferynska, I; Skotnicki, A; Stella-Holowiecka, B; Sulek, K; Trelinski, J; Warzocha, K; Wiater, E; Zawilska, K1
Blonski, JZ; Boguradzki, P; Calbecka, M; Dmoszynska, A; Dwilewicz-Trojaczek, J; Gora-Tybor, J; Jamroziak, K; Kloczko, J; Kowal, M; Kuliczkowski, K; Lech-Maranda, E; Moskwa, A; Piotrowska, M; Piszcz, J; Potoczek, S; Robak, T; Skotnicki, AB; Stella-Holowiecka, B; Sulek, K; Warzocha, K; Zawilska, K1
Borowiak, A; Błoński, JZ; Cebula-Obrzut, B; Kiliańska, ZM; Kotkowska, A; Robak, T; Rogalińska, M; Smolewski, P; Wawrzyniak, E; Żołnierczyk, JD1
Brandberg, Y; Gill, D; Hammerström, J; Hertzberg, M; Johansson, H; Juliusson, G; Jønsson, V; Karlsson, K; Liliemark, J; McLennan, R; Mulligan, SP; Norman, J; Strömberg, M; Sundström, G; Uggla, B; Wallvik, J1
Błoński, JZ; Góralski, P; Hartman, M; Kiliańska, ZM; Koceva-Chyła, A; Piekarski, H; Robak, P; Robak, T; Rogalińska, M; Rogalska, A; Wawrzyniak, E1
Gurram, V; Kaliyaperumal, M; Kreitman, RJ; Lakshman, MK; Martínez Montemayor, MM; Pottabathini, N; Relangi, SS; Satishkumar, S; Sharma, S; Vuram, PK; Yang, L; Zhou, H1
Arana Echarri, A; Beyaert, M; Bol, V; Bontemps, F; Michaux, L; Saussoy, P; Smal, C; Starczewska, E; Van Den Neste, E; Vekemans, MC1
Bednarek, JD; Blonski, JZ; Goralski, P; Hanausek, M; Kilianska, ZM; Piekarski, H; Robak, T; Rogalinska, M; Walaszek, Z; Wozniak, K1
Berchem, G; Bouzar, AB; Boxus, M; Bron, D; Burny, A; Chatelain, B; Chatelain, C; Defoiche, J; Lagneaux, L; Macallan, D; Pettengell, R; Willems, L; Willis, F1
Chtioui, H; Lämmle, B; Lauterburg, BH; Millius, C1
Blonski, JZ; Dmoszynska, A; Gora-Tybor, J; Jamroziak, K; Konopka, L; Palacz, A; Robak, T; Warzocha, K; Wawrzyniak, E1
Castejón, R; Citores, MJ; García-Marco, JA; Vargas, JA; Villarreal, M; Yebra, M1
Andreola, G; Bertolini, F; Billio, A; Calabrese, L; Fabbri, A; Frigeri, F; Laszlo, D; Martinelli, G; Rabascio, C; Radice, D; Rigacci, L; Saronni, L1
Błoński, JZ; Kiliańska, ZM; Robak, T; Wesierska-Gadek, J; Zolnierczyk, JD1
Beert, E; Bontemps, F; Connerotte, T; de Viron, E; Hermans, C; Knoops, L; Michaux, L; Saussoy, P; Smal, C; Van Den Neste, E; Vannuffel, P; Vekemans, MC1
Błoński, JZ; Góralski, P; Kiliańska, ZM; Komina, O; Piekarski, H; Robak, T; Rogalińska, M; Wesierska-Gadek, J; Zołnierczyk, JD1
Castejon, R; Citores, MJ; Garcia-Marco, JA; Rosado, S; Vargas, JA; Villarreal, M1
Polliack, A; Tadmor, T; Tam, CS1
Blonski, JZ; Calbecka, M; Ceglarek, B; Dmoszyñska, A; Dwilewicz-Trojaczek, J; Gora-Tybor, J; Hellmann, A; Jamroziak, K; Konopka, L; Kostyra, A; Lewandowski, K; Piotrowska, M; Piszcz, J; Potoczek, S; Robak, T; Seferynska, I; Stella-Holowiecka, B; Warzocha, K; Zawilska, K; Zdunczyk, A1
Bargetzi, MJ; Beretta, K; Brauchli, P; Gregor, M; Hanselmann, S; Heim, D; Himmelmann, A; Leupin, N; Rovo, A; Schuller, JC; Solenthaler, M; Zenhäusern, R1
Chocholska, S; Dmoszynska, A; Halicka, D; Klimek, P; Kowal, M; Podhorecka, M2
Bassi, S; Bertazzoni, P; Calabrese, L; Calleri, A; Gigli, F; Gregato, G; Laszlo, D; Liptrott, SJ; Martinelli, G; Nassi, L; Negri, M; Orlando, L; Preda, L; Pruneri, G; Rabascio, C; Radice, D; Sammassimo, S1
Miller, HJ; Saven, A; Schram, ED; Sigal, DS1
Baran, W; Batycka-Baran, A; Dzietczenia, J; Mazur, G1
Amsailale, R; Arts, A; Bastin-Coyette, L; Bontemps, F; Cardoen, S; de Viron, E; Smal, C; Van Den Neste, E1
Aguilar, J; Al-Katib, A; del Busto, R; Johnson, LB; Obeid, KM; Sharma, M; Szpunar, S1
Borowiak, A; Błoński, JZ; Cebula-Obrzut, B; Kiliańska, ZM; Komina, O; Robak, P; Smolewski, P; Węsierska-Gądek, J; Żołnierczyk, JD1
Fathi, AT; Hasserjian, R; Sadrzadeh, H1
Blonski, JZ; Franiak-Pietryga, I; Ghia, P; Janus, A; Korycka-Wolowiec, A; Kotkowska, A; Maciejewski, H; Mirowski, M; Robak, T; Salagacka, A; Wawrzyniak, E; Wolowiec, D1
Borowiec, M; Błoński, JZ; Franiak-Pietryga, I; Korycka-Wołowiec, A; Maciejewski, H; Mirowski, M; Robak, T; Sałagacka, A1
Almazi, JG; Christopherson, RI; Crossett, B; Kohnke, PL; Mactier, S1
Cebula-Obrzut, B; Robak, T; Smolewski, P; Wolska, A1
Błoński, JZ; Franiak-Pietryga, I; Góralski, P; Janus, A; Kiliańska, ZM; Maciejewski, H; Mirowski, M; Piekarski, H; Robak, P; Robak, T; Rogalińska, M1
Bosch, F; Campo, E; Colomer, D; Giné, E; López-Guillermo, A; Montserrat, E; Rozman, M; Villamor, N1
Aivado, M; Burger, J; Finke, J; Haas, R; Henze, L; Schulte, K1
Boński, JZ; Dmoszyńska, A; Dwilewicz-Trojaczek, J; Góra-Tybor, J; Hellmann, A; Kasznicki, M; Konopka, L; Robak, T; Wołowiec, D1
Escribano, L; Núñez, R; Orfao, A; Pérez de Oteyza, J1
Bartkowiak, J; Biernat, W; Krykowski, E; Robak, E; Robak, T1
Błoński, JZ; Dwilewicz-Trojaczek, J; Góra-Tybor, J; Kasznicki, M; Robak, T; Stella-Hołowiecka, B; Wołowiec, D1
Di Raimondo, F; Ferrajoli, A; Keating, MJ; Lerner, S; Montillo, M; Morra, E; O'Brien, S; Tedeschi, A1
Byrd, JC; Larson, RA; Peterson, B; Piro, L; Saven, A; Schiffer, C; Vardiman, JW1
Albertioni, F; Eriksson, S; Gruber, A; Karlsson, MO; Liliemark, J; Lindemalm, S; Wang, Y1
Pettitt, AR1
Bartkowiak, J; Kordek, R; Korycka, A; Robak, T; Smolewski, P; Szmigielska-Kapłon, A; Wawrzyniak, E1
Blonski, JZ; Całbecka, M; Ceglarek, B; Dmoszyńska, A; Dwilewicz-Trojaczek, A; Gora-Tybor, J; Hellmann, A; Kasznicki, M; Komarnicki, M; Konopka, L; Lewandowski, K; Moskwa, A; Robak, T; Sokołowska, B; Sułek, K; Tomaszewska, A1
Gartenhaus, RB; Nabhan, C; Tallman, MS1
Christopherson, RI; Mulligan, SP; Wilson, PK1
Armitage, JO; Hoelzer, D; Rummel, MJ; Tobinai, K1
Chiari, AC; Cintra, ML; de Souza, EM; Lorand-Metze, I; Pagnano, KB; Rossini, MS1
Caracciolo, F; Cecconi, N; Cervetti, G; Galimberti, S; Petrini, M1
Góra-Tybor, J; Jamroziak, K; Kordek, R; Majos, A; Rieske, P; Robak, P; Robak, T; Tybor, K; Urbańska-Ryś, H1
Aleskog, A; Höglund, M; Larsson, R; Laurell, A; Lindhagen, E; Nilsson, K; Nygren, P; Roos, G; Rosenquist, R; Sundström, C; Thunberg, U; Tobin, G1
Robak, T3
Bontemps, F; Cardoen, S; Ferrant, A; Rosier, JF; Smal, C; Van den Berghe, G; Van den Neste, E1
Błoński, JZ; Hanausek, M; Kiliańska, ZM; Robak, T; Rogalińska, M; Walaszek, Z1
Dziecioł, J; Kłoczko, J; Lemancewicz, D; Piszcz, J1
Arbiser, J; Battle, TE; Frank, DA1
Cebula, B; Duechler, M; Linke, A; Robak, T; Schwarzmeier, JD; Shehata, M; Smolewski, P1
Blonski, JZ; Dmoszyñska, A; Góra-Tybor, J; Kasznicki, M; Robak, T; Skotñicki, A1
Biernat, W; Jeziorski, A; Krykowski, E; Robak, E; Robak, T1
Błoński, JZ; Chojnowski, K; Kasznicki, M; Robak, T; Szmigielska-Kapłon, A1
Bontemps, F; Cardoen, S; Offner, F; Van den Neste, E1
Boguradzki, P; Błoński, JZ; Ceglarek, B; Dmoszyńska, A; Dwilewicz-Trojaczek, J; Góra-Tybor, J; Hellmann, A; Kasznicki, M; Konopka, L; Kuliczkowski, K; Lewandowski, K; Nowak, W; Robak, T; Skotnicki, AB; Sułek, K; Warzocha, K; Wojtaszko, M; Zdziarska, B1
Blonski, JZ; Calbecka, M; Ceglarek, B; Dmoszynska, A; Dwilewicz-Trojaczek, J; Gora-Tybor, J; Jamroziak, K; Kasznicki, M; Kloczko, J; Konopka, L; Kowal, M; Kuliczkowski, K; Robak, T; Skotnicki, AB; Stella-Holowiecka, B; Sulek, K; Tomaszewska, A; Warzocha, K; Zawilska, K1
Bohlius, J; Greil, R; Pall, G; Richards, S; Schwarzer, G; Steurer, M2
Bednarek, J; Blonski, JZ; Hanausek, M; Kilianska, ZM; Kobylinska, A; Robak, T; Walaszek, Z1
Ballabeni, P; Cerny, T; Fey, M; Hess, U; Laurencet, F; Luthi, JM; Plancherel, C; Rufener, B; Zulian, GB1
Bontemps, F; Ferrant, A; Lisart, S; Maerevoet, M; Smal, C; Van Den Neste, E1
Cebula, B; Linke, A; Robak, P; Robak, T; Smolewski, P1
Błonski, JZ; Góra-Tybor, J; Jesionek-Kupnicka, D; Kasznicki, M; Kordek, R; Lech-Marańda, E; Robak, T; Szmigielska-Kapłon, A1
Costantini, S; Delannoy, A; Deneys, V; Ferrant, A; Francart, J; Hagemeijer, A; Michaux, L; Robert, A; Robin, V; Sonet, A; Stul, M; Van Den Neste, E; Vandenberghe, P1
Błoński, JZ; Cebula, B; Grzybowska-Izydorczyk, O; Robak, T; Smolewski, P1
Fukui, E; Funada, Y; Gomyo, H; Hanioka, K; Kajimoto, K; Koizumi, T; Maeda, A; Mizuno, I; Murayama, T; Ogura, M1
Dabrowska, M; Dzieciol, J; Kloczko, J; Lemancewicz, D; Piszcz, JA; Rusak, M1
Ashique, A; Begleiter, A; Israels, LG; Johnston, JB; Lee, K; Mowat, MR; Verburg, L1
Juliusson, G1
Alessi-Severini, S; Belch, AR; Gati, WP; Paterson, AR1
Cull, G; Hopkins, JA; Howe, DJ; Johnson, SA; Phillips, MJ; Richardson, DS1
Bosly, A; Delannoy, A; Deneys, V; Ferrant, A; Gala, JL; Martiat, P; Michaux, JL; Schieff, JM1
Mejer, J; Munch-Petersen, B; Nielsen, SE1
Brugiatelli, M; Callea, I; Callea, V; Iacopino, P; Messina, G; Morabito, F; Nobile, F; Rodinò, A1
Hiddemann, W; Pott-Hoeck, C1
Hakimian, D; Hogan, DK; Rademaker, A; Rose, E; Tallman, MS; Variakojis, D; Zanzig, C1
Croy, D; Fleischman, RA1
Arnér, ES; Brosjö, O; Eriksson, S; Gunvén, P; Juliusson, G; Liliemark, J; Spasokoukotskaja, T1
del Giglio, A; Keating, M; O'Brien, S1
Beutler, E; Kosty, M; Lemon, RH; Piro, LD; Saven, A1
Piatkowska-Jakubas, B; Skotnicki, AB1
Andreeff, M; Beran, M; Estey, E; Kantarjian, H; Keating, M; Koller, C; O'Brien, S; Pierce, S; Robertson, B1
Betticher, DC; Gratwohl, A; Haberthür, C; Pless, M; Speck, B; Tichelli, A1
Piro, LD; Saven, A2
Piro, LD1
Juliusson, G; Liliemark, J4
Piro, L; Saven, A1
Ciepłuch, H; Hałaburda, K; Hellmann, A; Zaucha, JM1
Csoka, K; de la Torre, M; Fridborg, H; Kristensen, J; Larsson, R; Liliemark, J; Nygren, P1
Delannoy, A; Doyen, C; Ferrant, A; Martiat, P; Michaux, JL; Montfort, L; Sokal, G1
Bosly, A; Brousset, P; Delannoy, A; Pris, J; Riga-Huguet, F; Schlaifer, D1
Albertioni, F; Juliusson, G; Liliemark, J; Pettersson, B; Reichelová, V1
Bendandi, M; Buzzi, M; Farabegoli, P; Martinelli, G; Ottaviani, E; Salvucci, M; Tosi, P; Visani, G; Zaccaria, A; Zinzani, PL1
Arnér, ES; Eriksson, S; Juliusson, G; Liliemark, J; Spasokoukotskaja, T1
Chubb, S; Ford, R; Hittelman, WN; Meyn, RE; Plunkett, W; Robertson, LE; Story, M1
Cunningham, D; Dorland, E; Hickish, T; Judson, I; Lister, TA; Millar, BC; Oza, A; Roldan, A; Serafinowski, P1
Carrera, CJ; Carson, DA; Kawasaki, H; Kipps, TJ; Piro, LD; Saven, A1
Delannoy, A; Ferrant, A; Hanique, G1
Lemon, RH; Piro, LD; Saven, A1
Larson, RA; Spielberger, RT; Stock, W1
Beran, M; Estey, E; Kantarjian, H; Keating, MJ; Koller, C; O'Brien, S; Robertson, LB1
Dann, EJ; Gillis, S; Okon, E; Polliack, A; Rachmilewitz, EA; Rund, D1
Keating, MJ; Lerner, S; O'Brien, S; Robertson, LE; Seymour, JF1
Hogan, DK; Nelson, MC1
Brown, RD; Gibson, J; Joshua, DE; Luo, XF; Petersen, AJ; Pope, B; Schutz, L; Wiley, JS1
Bosly, A; Delannoy, A; Ferrant, A; Filleul, B; Martiat, P; Michaux, JL; Mineur, P; Montfort, L; Straetmans, N; Van Den Neste, E; Vandercam, B1
Astrow, AB1
Busuttil, DP; Chasty, RC; Copplestone, JA; Fraser, M; Prentice, AG1
Christiansen, I; Elmhorn-Rosenborg, A; Hansen, MM; Johnson, S; Juliusson, G; Kimby, E; Liliemark, J1
Geisen, F; Konwalinka, G; Michlmayr, G; Schirmer, M1
Hakimian, D; Tallman, MS1
Saven, A1
Krykowski, E; Robak, T; Warzocha, K1
Brugiatelli, M; Callea, V; Dmoszynska, A; Holowiecka, B; Holowiecki, J; Jaksic, B; Krieger, O; Labar, B; Lutz, D; Morabito, F; Planinc-Peraica, A1
Lärfars, G; Samuelsson, J; Udén-Blohmé, AM1
Albertioni, F; Liliemark, J; Reichelova, V1
Gartenhaus, RB; Hoffman, M; Janson, D; Rai, KR; Wang, P1
Bashford, J; Bunce, I; Dodds, A; Eliadis, P; Firkin, F; Frost, T; Goldstein, D; Grigg, A; Kelly, C; Kimber, R; Lee, N; Lowenthal, R; Moore, D; Morton, J; Mulligan, S; Parkin, J; Rentoul, A; Rodwell, R; Rooney, K; Stone, J; Taylor, K; Wright, S1
Błasinka-Morawiec, M; Ceglarek, B; Dmoszynska, A; Durzynski, T; Dwilewicz-Trojaczek, J; Grieb, P; Hansz, J; Hellmann, A; Kasznicki, M; Komarnicki, M; Konopka, L; Kopec, I; Kotlarek-Haus, S; Krykowski, E; Lewandowski, K; Maj, S; Mazur, G; Potemski, P; Płuzanska, A; Robak, T; Sikorska, A; Skotnicki, AB; Urasinski, I; Zaucha, JM; Zdziarska, B1
Begleiter, A; Israels, LG; Johnston, JB; Lee, K; Mowat, MR; Verburg, L; Wang, H1
Adam, Z; Hejlová, N; Vorlícek, J1
Gjedde, SB; Hansen, MM; Juliusson, G1
Kroft, SH; Peterson, LC; Shaw, JM; Tallman, MS; Thangavelu, M1
Kantarjian, H; Keating, MJ; O'Brien, S1
Begleiter, A; Liliemark, JO; Plunkett, W; Reed, JC1
Dutcher, JP; Makower, D; Venkatraj, U; Wiernik, PH1
Bloński, J; Fabianowska-Majewska, K; Krykowski, E; Robak, T; Warzocha, K1
Błasińska-Morawiec, M; Hellmann, A; Konopka, L; Krykowski, E; Robak, T1
Dighiero, G1
Hiddemann, W; Pott, C1
Bergmann, L1
Hilgenfeld, E; Jäger, U; Knauf, WU; Mitterbauer, M; Wilfing, A1
Hotta, T; Kinoshita, T; Kobayashi, Y; Kozuru, M; Narabayashi, M; Ogura, M; Ohashi, Y; Suzuki, R; Tobinai, K; Uike, N1
Berrocal, E; Briz, M; Castejón, R; Durantez, A; Fernández, MN; Gea-Banacloche, JC; Romero, Y; Vargas, JA1
Blasinska-Morawiec, M; Dabkowski, J; Robak, E; Robak, T; Sysa-Jedrzejowska, A1
al-Katib, AM; Almatchy, VP; Katato, K; Liu, KZ; Mantsch, HH; Mohammad, RM; Schultz, CP; Varterasian, M; Wall, N1
Albertioni, F; Eriksson, S; Juliusson, G; Liliemark, J; Lindemalm, S; Pettersson, B; Reichelova, V1
Filangeri, M; Morabito, F; Oliva, B; Sculli, G2
Polliack, A1
Albertioni, F; Eriksson, S; Juliusson, G; Liliemark, J; Lindemalm, S1
Błasińska-Morawiec, M; Błoński, JZ; Dmoszyńska, A; Hansz, J; Kaźmierczuk, M; Komarnicki, M; Konopka, L; Kotlarek-Haus, S; Krykowski, E; Nowak, WS; Robak, T; Roliński, J; Skotnicki, AB; Trepińska, E; Urasiński, I; Zdziarska, B1
Al-Katib, AM; Johnston, JB; Liu, KZ; Mantsch, HH; Mohammad, RM; Schultz, CP1
Rai, KR1
Cheson, BD1
Albertioni, F; Edlund, C; Juliusson, G; Liliemark, J1
Bromidge, TJ; Howe, DJ; Johnson, SA; Rule, SA; Turner, DL1
Betticher, DC; Cerny, T; Fey, MF; Hess, U; Hsu Schmitz, SF; Ratschiller, D; Tichelli, A; Tobler, A; von Rohr, A; Wernli, M; Zulian, G1
Delannoy, A; Devogelaer, JP; Houssiau, FA1
Callea, I; Console, G; Filangeri, M; Messina, G; Morabito, F; Sculli, G1
Al-Katib, A; Beck, FW; Hamdy, N; Katato, K; Mohammad, RM; Wall, N1
Arat, M; Beksaç, M; Idilman, R1
Koski, T; Vilpo, J; Vilpo, L2
Alberto, P; Betticher, DC; Guetty-Alberto, M; Iten, PA; Laurencet, FM; Zulian, GB1
Błasińska-Morawiec, M; Błoński, JZ; Robak, T; Skotnicki, AB; Urbańska-Ryś, H1
Delannoy, A; Gala, JL; Guiot, Y; Martiat, P; Philippe, M; Scheiff, JM1
Błasińska-Morawiec, M; Błoński, JZ; Dmoszyńska, A; Robak, T1
Bontemps, F; Cardoen, S; Delacauw, A; Deneys, V; Ferrant, A; Gillis, E; Leveugle, P; Louviaux, I; Scheiff, JM; Van den Berghe, G; Van Den Neste, E1
Dmoszyńska, A; Legiec, W; Wach, M1
Bosanquet, AG; Copplestone, JA; Johnson, SA; Orchard, JA; Oscier, DG; Povey, SJ; Smith, AG1
Albertioni, F; Eriksson, S; Liliemark, J; Lotfi, K; Månsson, E; Peterson, C; Pettersson, B; Spasokoukotskaja, T1
Cawley, JC; Pettitt, AR; Sherrington, PD2
Krook, JE; Levitt, R; Li, CY; Michalak, JC; Schroeder, G; Tefferi, A; Tschetter, LK; Witzig, TE1
Barrett, J; Cheson, BD; Freidlin, B; Vena, DA1
Bloński, JZ; Ceglarek, B; Dmoszyńska, A; Dwilewicz-Trojaczek, J; Grieb, P; Hansz, J; Hellmann, A; Holowiecki, J; Kasznicki, M; Komarnicki, M; Konopka, L; Kroll, R; Kuliczkowski, K; Lewandowski, K; Nowak, W; Potoczek, S; Robak, T; Skotnicki, AB; Soroka-Wojtaszko, M; Tomaszewska, A; Zdziarska, B1
Ahmad, I; Al-Katib, AM; Beck, FW; Liu, KZ; Mantsch, HH; Mohammad, RM; Wall, NR1
Bosanquet, AG; Bosanquet, MI1
Ahmad, I; Al-Katib, AM; Beck, FW; Mohammad, RM1
Błasińska-Morawiec, M; Błoński, JZ; Korycka, A; Robak, T; Wierzbowska, A1
André, M; Bosly, A; Coche, E; Delannoy, A; Doyen, C; Duprez, T; Ferrant, A; Louviaux, I; Michaux, JL; Michaux, L; Mineur, P; Sonet, A; Straetmans, N; Van Den Neste, E; Venet, C1
Kipps, TJ1
Blasińska-Morawiec, M; Bloński, JZ; Ceglarek, B; Dmoszyńska, A; Dwilewicz-Trojaczek, J; Grieb, P; Hellmann, A; Kasznicki, M; Konopka, L; Kotlarek-Haus, S; Krykowski, E; Maj, S; Mrugala-Spiewak, H; Nowak, W; Potoczek, S; Robak, T; Skotnicki, AB; Urasiński, I; Zdziarska, B1
Adachi, S; Carrera, CJ; Carson, DA; Chao, Q; Cottam, HB; Genini, D; Leoni, LM; Rose, DW1
Johnson, SA; Thomas, W1
Weiss, MA1
Bloński, JZ; Dmoszyńska, A; Kasznicki, M; Robak, T; Skotnicki, AB1
Błoński, JZ; Góra-Tybor, J; Kasznicki, M; Lech-Marańda, E; Robak, T1
Błoński , JZ; Kasznicki, M; Robak, T1
Addo, F; Allmer, C; Geyer, SM; Krook, JE; Levitt, R; Li, CY; Mailliard, JA; Michalak, JC; Reeder, CB; Schaefer, PL; Tefferi, A; Witzig, TE1
Boguradzki, P; Błoński, JZ; Calbecka, M; Ceglarek, B; Dmoszyńska, A; Dwilewicz-Trojaczek, J; Góra-Tybor, I; Kasznicki, M; Konopka, L; Kuliczkowski, K; Moskwa-Sroka, B; Nowak, W; Robak, T; Skotnicki, AB; Stella-Hołowiecka, B; Sułek, J; Wołowiec, D1
Bartkowiak, J; Błonski, JZ; Kasznicki, M; Kordek, R; Robak, T; Wawrzyniak, E1
Boehrer, S; Chow, KU; Hoelzer, D; Mitrou, PS; Rummel, MJ; Schneider, B; Seipelt, G; Sommerlad, WD; Weidmann, E1
Bontemps, F; Cardoen, S; Delacauw, A; Ferrant, A; Husson, B; Rosier, JF; Van den Berghe, G; Van Den Neste, E1
Celsing, F; Cristiansen, I; Delannoy, A; Johnson, SA; Juliusson, G; Karlsson, K; Kimby, E; Lärfars, G; Liliemark, J; Luthman, M; Nilsson, G; Porwit, A; Strömberg, M; Sundström, G; Tidefelt, U; Wallvik, J1
Kontoyiannis, DP; Samonis, G1
Kasznicki, M; Robak, T1
Bosanquet, AG; Bosanquet, MI; Daniel, PT; Dörken, B; Essmann, F; Head, DJ; Sturm, I; Wieder, T1
Blonski, JZ; Gora-Tybor, J; Robak, T1
Beutler, E; Carrera, CJ; Carson, DA; Kay, AC; Piro, LD; Saven, A; Thurston, D1
Carrera, CJ; Carson, DA; Cottam, HB; Esparza, LM; Kipps, TJ; Wasson, DB1
Elmhorn-Rosenborg, A; Juliusson, G; Liliemark, J1
Kantarjian, H; Keating, MJ; Koller, C; O'Brien, S; Plunkett, W; Robertson, L1
Gribbin, TE1
Beutler, E; Carrera, CJ; Carson, DA; Piro, LD; Saven, A; Terai, C1
Beutler, E; Carrera, CJ; Carson, DA; Piro, LD; Wasson, DB1

Reviews

38 review(s) available for cladribine and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Beyond hairy cell: the activity of cladribine in other hematologic malignancies.
    Blood, 2010, Oct-21, Volume: 116, Issue:16

    Topics: Antineoplastic Agents; Cladribine; Hematologic Neoplasms; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia

2010
Simultaneous diagnosis of hairy cell leukemia and chronic lymphocytic leukemia/small lymphocytic lymphoma: a frequent association?
    Leukemia, 2002, Volume: 16, Issue:8

    Topics: Antimetabolites, Antineoplastic; B-Lymphocytes; Cell Lineage; Cladribine; Combined Modality Therapy; Comorbidity; Gene Rearrangement, B-Lymphocyte; Genes, Immunoglobulin; Hematopoietic Stem Cell Transplantation; Humans; Immunophenotyping; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Mass Screening; Middle Aged; Neoplasms, Multiple Primary; Neoplastic Stem Cells; Pentostatin; Prospective Studies; Remission Induction; Salvage Therapy; Transplantation, Autologous

2002
Mechanism of action of purine analogues in chronic lymphocytic leukaemia.
    British journal of haematology, 2003, Volume: 121, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Division; Cladribine; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Phosphorylation; Tumor Suppressor Protein p53; Vidarabine

2003
Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era.
    Leukemia research, 2004, Volume: 28, Issue:5

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Rituximab; Vidarabine

2004
Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone.
    International journal of hematology, 2004, Volume: 79, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Mitoxantrone; Treatment Outcome

2004
The place of cladribine in the treatment of chronic lymphocytic leukemia: a 10-year experience in Poland.
    Annals of hematology, 2005, Volume: 84, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms, Second Primary; Poland; Randomized Controlled Trials as Topic

2005
Therapy of chronic lymphocytic leukemia with purine analogs and monoclonal antibodies.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2005, Volume: 32, Issue:1

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antigens, CD; Antigens, Neoplasm; Antineoplastic Agents; CD52 Antigen; Cladribine; Clinical Trials as Topic; Glycoproteins; Humans; Immunotherapy; Leukemia, Lymphocytic, Chronic, B-Cell; Purines; Random Allocation; Rituximab; Time Factors; Vidarabine

2005
Old and new insights into the mechanisms of action of two nucleoside analogs active in lymphoid malignancies: fludarabine and cladribine (review).
    International journal of oncology, 2005, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Membrane; Cell Proliferation; Cell Survival; Cladribine; DNA; DNA Damage; DNA Repair; DNA-Directed DNA Polymerase; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Models, Biological; Models, Chemical; Nucleosides; RNA; Signal Transduction; Tumor Suppressor Protein p53; Vidarabine

2005
Single-agent purine analogues for the treatment of chronic lymphocytic leukaemia: a systematic review and meta-analysis.
    Cancer treatment reviews, 2006, Volume: 32, Issue:5

    Topics: Anemia, Hemolytic; Antineoplastic Agents; Cladribine; Disease-Free Survival; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Vidarabine

2006
Purine antagonists for chronic lymphocytic leukaemia.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Antineoplastic Agents; Chlorambucil; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Randomized Controlled Trials as Topic; Vidarabine

2006
Immunological and genetic abnormalities in chronic lymphocytic leukaemia. Impact of the purine analogues.
    Drugs, 1994, Volume: 47 Suppl 6

    Topics: Antineoplastic Agents; Chromosome Aberrations; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 13; Cladribine; Humans; Immunity, Cellular; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine

1994
Purine analogs in the treatment of low-grade lymphomas and chronic lymphocytic leukemias.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cladribine; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Pentostatin; Purines; Vidarabine

1995
Advances in the biology and treatment of B-cell chronic lymphocytic leukemia.
    Blood, 1995, Jan-15, Volume: 85, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Bone Marrow Transplantation; Chlorambucil; Chromosome Aberrations; Cladribine; Humans; Immunologic Factors; Immunotherapy; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Vidarabine

1995
2-Chlorodeoxyadenosine in the treatment of hairy cell leukemia and chronic lymphocytic leukemia.
    Leukemia & lymphoma, 1993, Volume: 11 Suppl 2

    Topics: Cladribine; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell

1993
2-Chlorodeoxyadenosine: treatment of hairy cell leukemia, chronic lymphocytic leukemia, and lymphocytic lymphoma.
    Seminars in hematology, 1993, Volume: 30, Issue:4 Suppl 6

    Topics: Cladribine; Clinical Trials as Topic; Follow-Up Studies; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell

1993
Nucleoside analogs in treatment of chronic lymphocytic leukemia.
    Leukemia & lymphoma, 1993, Volume: 10 Suppl

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Survival Rate; Vidarabine

1993
2-Chlorodeoxyadenosine: a new nucleoside agent effective in the treatment of lymphoid malignancies.
    Leukemia & lymphoma, 1993, Volume: 10 Suppl

    Topics: Cladribine; Humans; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous

1993
The role of cladribine in the treatment of lymphoid malignancies.
    Oncology nursing forum, 1995, Volume: 22, Issue:9

    Topics: Antineoplastic Agents; Cladribine; Drug Monitoring; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Oncology Nursing; Patient Care Planning

1995
Current results and prospective trials of cladribine in chronic lymphocytic leukemia.
    Seminars in hematology, 1996, Volume: 33, Issue:1 Suppl 1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cladribine; Clinical Trials as Topic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Prospective Studies; Vidarabine

1996
The Scripps Clinic experience with cladribine (2-CdA) in the treatment of chronic lymphocytic leukemia.
    Seminars in hematology, 1996, Volume: 33, Issue:1 Suppl 1

    Topics: Alkylation; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Drug Resistance, Neoplasm; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine

1996
[Treatment of chronic lymphatic leukemia].
    Vnitrni lekarstvi, 1996, Volume: 42, Issue:8

    Topics: Antineoplastic Agents; Cladribine; Humans; Interferon-alpha; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prognosis; Vidarabine

1996
Purine analogs in chronic lymphocytic leukemia and Waldenström's macroglobulinemia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7 Suppl 6

    Topics: Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Purine Nucleosides; Vidarabine; Waldenstrom Macroglobulinemia

1996
Why do drugs work in CLL?
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 2

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Cladribine; Clinical Trials as Topic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine Phosphate

1996
Adverse and beneficial immunological effects of purine nucleoside analogues.
    Hematology and cell therapy, 1996, Volume: 38 Suppl 2

    Topics: Animals; Antineoplastic Agents; Cladribine; Humans; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Purine Nucleosides; Vidarabine

1996
Purine analogs in the treatment of chronic lymphocytic leukemia.
    Leukemia, 1997, Volume: 11 Suppl 2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Clinical Trials as Topic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine

1997
Present status of purine analogs in the therapy of chronic lymphocytic leukemias.
    Leukemia, 1997, Volume: 11 Suppl 2

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prognosis; Recurrence; Remission Induction; Vidarabine

1997
Is there a place for 2-CDA in the treatment of B-CLL?
    Leukemia, 1997, Volume: 11 Suppl 2

    Topics: Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Drug Resistance, Neoplasm; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Recurrence; Thrombocytopenia; Vidarabine

1997
Hairy cell leukemia and allied chronic lymphoid leukemias: current knowledge and new therapeutic options.
    Leukemia & lymphoma, 1997, Volume: 26 Suppl 1

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Cladribine; Diagnosis, Differential; Humans; Interferon-alpha; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Lymphoma, Non-Hodgkin; Pentostatin; Prognosis

1997
Cladribine for the treatment of hairy cell leukemia and chronic lymphocytic leukemia.
    Seminars in oncology, 1998, Volume: 25, Issue:3 Suppl 7

    Topics: Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Remission Induction; Treatment Outcome

1998
Therapy for previously untreated chronic lymphocytic leukemia: a reevaluation.
    Seminars in hematology, 1998, Volume: 35, Issue:3 Suppl 3

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Randomized Controlled Trials as Topic; Vidarabine

1998
Chronic lymphocytic leukemia.
    Current opinion in hematology, 2000, Volume: 7, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; CD79 Antigens; Chromosome Aberrations; Chromosomes, Human; Cladribine; Combined Modality Therapy; Cytokines; Female; Genes, Immunoglobulin; Genes, p53; Genetic Therapy; Hematopoietic Stem Cell Transplantation; Humans; Immunologic Deficiency Syndromes; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Neoplastic Stem Cells; Prognosis; Risk Factors; Vidarabine

2000
Therapeutic potential of purine analogue combinations in the treatment of lymphoid malignancies.
    Hematological oncology, 2000, Volume: 18, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Clinical Trials as Topic; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Pentostatin; Purines; Vidarabine

2000
Novel treatment strategies in chronic lymphocytic leukemia.
    Current oncology reports, 2001, Volume: 3, Issue:3

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cladribine; Cyclophosphamide; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Pentostatin; Randomized Controlled Trials as Topic; Sex Factors; Vidarabine

2001
Cladribine in the treatment of chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:5-6

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell

2001
Infectious complications of purine analog therapy.
    Current opinion in infectious diseases, 2001, Volume: 14, Issue:4

    Topics: Antimetabolites, Antineoplastic; Cladribine; Humans; Immune Tolerance; Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine Phosphate

2001
Alkylating agents and nucleoside analogues in the treatment of B cell chronic lymphocytic leukemia.
    Leukemia, 2002, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Cladribine; Drug Therapy, Combination; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Recurrence, Local; Nucleosides; Survival Rate; Treatment Failure; Vidarabine

2002
New purine analogues for the treatment of chronic B-cell malignancies.
    Henry Ford Hospital medical journal, 1991, Volume: 39, Issue:2

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine

1991
Activity of 2-chloro-2'-deoxyadenosine in chronic lymphocytic leukemia, hairy cell leukemia, and autoimmune hemolytic anemia.
    Advances in experimental medicine and biology, 1989, Volume: 253A

    Topics: 2-Chloroadenosine; Adenosine Deaminase; Anemia, Hemolytic, Autoimmune; Cladribine; Deoxyadenosines; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell

1989

Trials

49 trial(s) available for cladribine and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Rituximab, cladribine, and cyclophosphamide (RCC) induction with rituximab maintenance in chronic lymphocytic leukemia: PALG - CLL4 (ML21283) trial.
    European journal of haematology, 2018, Volume: 100, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Cladribine; Cyclophosphamide; Female; Humans; Immunophenotyping; Kaplan-Meier Estimate; Leukemia, Lymphocytic, Chronic, B-Cell; Maintenance Chemotherapy; Male; Neoplasm Staging; Prognosis; Proportional Hazards Models; Remission Induction; Rituximab; Treatment Outcome

2018
Immune thrombocytopenia in patients with chronic lymphocytic leukemia treated with cladribine-based regiments or chlorambucil--follow-up of PALG-CLL randomized trials.
    European journal of haematology, 2013, Volume: 91, Issue:1

    Topics: Aged; Chlorambucil; Cladribine; Female; Follow-Up Studies; Hemorrhage; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prevalence; Retrospective Studies; Thrombocytopenia; Time Factors; Treatment Outcome

2013
Long-term results of the Polish Adult Leukemia Group PALG-CLL2 phase III randomized study comparing cladribine-based combinations in chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cladribine; Cyclophosphamide; Humans; Incidence; Leukemia, Lymphocytic, Chronic, B-Cell; Mitoxantrone; Neoplasms, Second Primary; Treatment Outcome

2014
In vivo and ex vivo responses of CLL cells to purine analogs combined with alkylating agent.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cladribine; Cyclophosphamide; DNA Fragmentation; Electrophoresis, Agar Gel; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Male; Middle Aged; Vidarabine

2013
Cladribine prolongs progression-free survival and time to second treatment compared to fludarabine and high-dose chlorambucil in chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:12

    Topics: Aged; Antineoplastic Agents; Chlorambucil; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Staging; Quality of Life; Retreatment; Treatment Outcome; Vidarabine

2014
Relationship between in vitro drug sensitivity and clinical response of patients to treatment in chronic lymphocytic leukemia.
    International journal of oncology, 2015, Volume: 46, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Cells, Cultured; Cladribine; Cyclophosphamide; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Male; Middle Aged; Treatment Outcome; Vidarabine

2015
Expression of the human concentrative nucleotide transporter 1 (hCNT1) gene correlates with clinical response in patients affected by Waldenström's Macroglobulinemia (WM) and small lymphocytic lymphoma (SLL) undergoing a combination treatment with 2-chlor
    Leukemia research, 2010, Volume: 34, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cladribine; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Membrane Transport Proteins; Middle Aged; Models, Biological; Prognosis; Rituximab; Treatment Outcome; Waldenstrom Macroglobulinemia

2010
Comparison of cladribine plus cyclophosphamide with fludarabine plus cyclophosphamide as first-line therapy for chronic lymphocytic leukemia: a phase III randomized study by the Polish Adult Leukemia Group (PALG-CLL3 Study).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-10, Volume: 28, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Cytogenetic Analysis; Female; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Staging; Remission Induction; Survival Rate; Treatment Outcome; Vidarabine

2010
Efficacy of rituximab and cladribine in patients with chronic lymphocytic leukemia and feasibility of stem cell mobilization: a prospective multicenter phase II trial (protocol SAKK 34/02).
    Leukemia & lymphoma, 2010, Volume: 51, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Remission Induction; Rituximab; Transplantation Conditioning; Treatment Outcome

2010
Changes in the apoptotic gene expression profile in CLL patients treated with rituximab combined with cladribine and cyclophosphamide-preliminary results.
    Leukemia research, 2012, Volume: 36, Issue:9

    Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cladribine; Cluster Analysis; Cyclophosphamide; DNA Mutational Analysis; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Genes, Immunoglobulin Heavy Chain; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Pilot Projects; Rituximab; V(D)J Recombination

2012
Cladribine combined with cyclophosphamide is highly effective in the treatment of chronic lymphocytic leukemia.
    The hematology journal : the official journal of the European Haematology Association, 2002, Volume: 3, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm, Residual; Neutropenia; Opportunistic Infections; Remission Induction; Survival Analysis; Thrombocytopenia; Treatment Outcome

2002
Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia.
    Cancer, 2003, Jan-01, Volume: 97, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Disease-Free Survival; Female; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Leukopenia; Male; Middle Aged; Neoplasm Staging; Neutropenia; Salvage Therapy; Thrombocytopenia; Treatment Outcome

2003
A phase II study of cladribine treatment for fludarabine refractory B cell chronic lymphocytic leukemia: results from CALGB Study 9211.
    Leukemia, 2003, Volume: 17, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cladribine; Confidence Intervals; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Neoplasm Staging; Patient Selection; Survival Rate; Time Factors; Vidarabine

2003
Role of low-dose 2-CdA in refractory or resistant lymphoplasmocytic lymphoma.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:4

    Topics: Aged; Antineoplastic Agents; Cladribine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Infusions, Intravenous; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Probability; Prognosis; Prospective Studies; Risk Assessment; Severity of Illness Index; Survival Analysis; Treatment Outcome; Waldenstrom Macroglobulinemia

2004
The effect of subsequent therapies in patients with chronic lymphocytic leukemia previously treated with prednisone and either cladribine or chlorambucil.
    Haematologica, 2005, Volume: 90, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cladribine; Cross-Over Studies; Cyclophosphamide; Doxorubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Prednisone; Treatment Outcome; Vincristine

2005
Activity of cladribine combined with etoposide in heavily pretreated patients with indolent lymphoid malignancies.
    Chemotherapy, 2005, Volume: 51, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Etoposide; Female; Humans; Infections; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neutropenia; Recurrence; Survival Analysis; Treatment Outcome

2005
Comparison of cladribine plus prednisone with chlorambucil plus prednisone in patients with chronic lymphocytic leukemia. Final report of the Polish Adult Leukemia Group (PALG CLL1).
    Medical science monitor : international medical journal of experimental and clinical research, 2005, Volume: 11, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cladribine; Cyclophosphamide; Doxorubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Prednisone; Survival Analysis; Vincristine

2005
Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (PALG C
    Blood, 2006, Jul-15, Volume: 108, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Female; Humans; Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Neutropenia; Remission Induction

2006
The multicenter trial SAKK 37/95 of cladribine, cyclophosphamide and prednisone in the treatment of chronic lymphocytic leukemias and low-grade non-Hodgkin's lymphomas.
    Acta haematologica, 2007, Volume: 117, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Hematologic Diseases; Humans; Immunocompromised Host; Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasms, Second Primary; Prednisone; Prospective Studies; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome

2007
Rituximab plus cladribine with or without cyclophosphamide in patients with relapsed or refractory chronic lymphocytic leukemia.
    European journal of haematology, 2007, Volume: 79, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Cladribine; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Recurrence; Rituximab; Survival Rate

2007
2-Chlorodeoxyadenosine (CdA) for patients with previously untreated chronic lymphocytic leukemia (CLL).
    Leukemia, 1995, Volume: 9, Issue:7

    Topics: Adult; Aged; Base Sequence; Blotting, Southern; Bone Marrow; Cladribine; Cohort Studies; Female; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Molecular Sequence Data; Neoplasm, Residual; Polymerase Chain Reaction; Remission Induction

1995
Cladribine in the treatment of relapsed or refractory chronic lymphocytic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:4

    Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Cladribine; Drug Administration Schedule; Drug Resistance; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Recurrence; Remission Induction; Survival Rate

1995
2-Chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:3

    Topics: Adult; Aged; Cladribine; Female; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Remission Induction; Thrombocytopenia

1995
2-Chlorodeoxyadenosine therapy in advanced chronic lymphocytic leukaemia.
    Nouvelle revue francaise d'hematologie, 1994, Volume: 36, Issue:4

    Topics: Aged; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neutropenia; Remission Induction; Salvage Therapy; Seizures; Survival Rate; Thrombocytopenia; Treatment Outcome

1994
2'-Chlorodeoxyadenosine: evaluation of a novel predominantly lymphocyte selective agent in lymphoid malignancies.
    British journal of cancer, 1993, Volume: 67, Issue:1

    Topics: Adult; Aged; Cladribine; Drug Evaluation; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Lymphoma, Non-Hodgkin; Male; Middle Aged

1993
2-Chlorodeoxyadenosine for patients with B-cell chronic lymphocytic leukemia resistant to fludarabine.
    The New England journal of medicine, 1993, Mar-18, Volume: 328, Issue:11

    Topics: Antineoplastic Agents; Cladribine; Drug Resistance; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine

1993
Survival of young patients with chronic lymphocytic leukemia failing fludarabine therapy: a basis for the use of myeloablative therapies.
    Leukemia & lymphoma, 1995, Volume: 18, Issue:5-6

    Topics: Adult; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Cladribine; Combined Modality Therapy; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Survival Analysis; Vidarabine

1995
Fludarabine in chronic leukaemia.
    Lancet (London, England), 1996, May-25, Volume: 347, Issue:9013

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Doxorubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prednisone; Vidarabine Phosphate

1996
Oral cladribine as primary therapy for patients with B-cell chronic lymphocytic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:7

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Blood Cell Count; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Remission Induction; Survival Rate

1996
2-Chlorodeoxyadenosine treatment in non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukemia resistant to conventional chemotherapy: results of a multicentric experience. International Society for Chemo-Immunotherapy.
    Annals of hematology, 1996, Volume: 73, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Cladribine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Lymph Nodes; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Staging; Survival Rate; Time Factors

1996
Intermittent 2-hour intravenous infusions of 2-chlorodeoxyadenosine in the treatment of 110 patients with refractory or previously untreated B-cell chronic lymphocytic leukemia.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Agents; Cladribine; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Staging; Recurrence; Vidarabine

1996
[Chronic lymphatic leukemia. Peroral cladribine as primary treatment].
    Ugeskrift for laeger, 1996, Nov-04, Volume: 158, Issue:45

    Topics: Aged; Antineoplastic Agents; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged

1996
Phase I study of cladribine (2-chlorodeoxyadenosine) in lymphoid malignancies. Cladribine Study Group.
    Japanese journal of clinical oncology, 1997, Volume: 27, Issue:3

    Topics: Aged; Antineoplastic Agents; Cladribine; Female; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphoma, T-Cell, Cutaneous; Male; Middle Aged; Neutropenia; Thrombocytopenia

1997
Pharmacokinetics of cladribine in plasma and its 5'-monophosphate and 5'-triphosphate in leukemic cells of patients with chronic lymphocytic leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:3

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Cladribine; Drug Administration Schedule; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Metabolic Clearance Rate; Middle Aged; Regression Analysis

1998
Bioavailability and bacterial degradation of rectally administered 2-chloro-2'-deoxyadenosine.
    Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:4-5

    Topics: Administration, Rectal; Aged; Bacteria; Biological Availability; Biotransformation; Cladribine; Feces; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Saliva

1995
Reduced dose of subcutaneous cladribine induces identical response rates but decreased toxicity in pretreated chronic lymphocytic leukaemia. Swiss Group for Clinical Cancer Research (SAKK).
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Cladribine; Cohort Studies; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prospective Studies; Remission Induction; Treatment Failure

1998
2-Chlorodeoxyadenosine (cladribine) in the treatment of elderly patients with B-cell chronic lymphocytic leukemia.
    Leukemia & lymphoma, 1999, Volume: 34, Issue:1-2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cladribine; Drug Administration Schedule; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Retrospective Studies

1999
Attempted reconstruction of the immune system using low doses of interleukin 2 in chronic lymphocytic leukemia patients treated with 2-chlorodeoxyadenosine: results of a pilot study.
    Leukemia & lymphoma, 1999, Volume: 34, Issue:3-4

    Topics: Antineoplastic Agents; CD3 Complex; CD4 Antigens; CD8 Antigens; Cladribine; Female; Humans; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Male; Pilot Projects; T-Lymphocytes

1999
Response to cladribine in previously treated patients with chronic lymphocytic leukaemia identified by ex vivo assessment of drug sensitivity by DiSC assay.
    British journal of haematology, 1999, Volume: 106, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cladribine; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Recurrence; Survival Analysis; Treatment Outcome

1999
Phase II study of 2-chlorodeoxyadenosine in combination with chlorambucil in previously untreated B-cell chronic lymphocytic leukemia.
    American journal of clinical oncology, 1999, Volume: 22, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cladribine; Disease Progression; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Neoplasm, Residual; Survival Analysis; United States

1999
Cladribine with or without prednisone in the treatment of previously treated and untreated B-cell chronic lymphocytic leukaemia - updated results of the multicentre study of 378 patients.
    British journal of haematology, 2000, Volume: 108, Issue:2

    Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Deoxyadenosines; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prednisone; Prospective Studies; Survival Analysis

2000
Phase I/II study of 2-chloro-2'-deoxyadenosine with cyclophosphamide in patients with pretreated B cell chronic lymphocytic leukemia and indolent non-Hodgkin's lymphoma.
    Leukemia, 2000, Volume: 14, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Survival Analysis

2000
Cladribine with prednisone versus chlorambucil with prednisone as first-line therapy in chronic lymphocytic leukemia: report of a prospective, randomized, multicenter trial.
    Blood, 2000, Oct-15, Volume: 96, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cladribine; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Incidence; Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Life Tables; Male; Middle Aged; Neutropenia; Poland; Prednisone; Prospective Studies; Remission Induction; Survival Rate; Thrombocytopenia; Treatment Outcome

2000
Cladribine in combination with mitoxantrone and cyclophosphamide(CMC) in the treatment of heavily pre-treated patients with advanced indolent lymphoid malignancies.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cladribine; Cyclophosphamide; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Mitoxantrone; Remission Induction; Salvage Therapy; Treatment Outcome

2001
A phase II study of sequential combination chemotherapy with cyclophosphamide, prednisone, and 2-chlorodeoxyadenosine in previously untreated patients with chronic lymphocytic leukemia.
    Leukemia, 2001, Volume: 15, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prednisone; Remission Induction

2001
Cladribine combined with cyclophosphamide and mitoxantrone as front-line therapy in chronic lymphocytic leukemia.
    Leukemia, 2001, Volume: 15, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cladribine; Cohort Studies; Cyclophosphamide; Female; Humans; Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitoxantrone; Pancytopenia; Treatment Outcome; Vomiting

2001
Oral cladribine for B-cell chronic lymphocytic leukaemia: report of a phase II trial with a 3-d, 3-weekly schedule in untreated and pretreated patients, and a long-term follow-up of 126 previously untreated patients.
    British journal of haematology, 2002, Volume: 116, Issue:3

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Cladribine; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Neoplasm, Residual; Opportunistic Infections; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome

2002
2-Chlorodeoxyadenosine treatment of low-grade lymphomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:3

    Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bacterial Infections; Bone Marrow Diseases; Cladribine; Deoxyadenosines; Drug Evaluation; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Male; Middle Aged; Remission Induction; Treatment Outcome

1992
Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine.
    The New England journal of medicine, 1992, Oct-08, Volume: 327, Issue:15

    Topics: 2-Chloroadenosine; Adult; Antineoplastic Agents; Cladribine; Deoxyadenosines; Drug Resistance; Female; Haptoglobins; Humans; Immunoglobulins; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Lymphocytes; Male; Middle Aged; Remission Induction; Vidarabine

1992

Other Studies

131 other study(ies) available for cladribine and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
The influence of venetoclax, used alone or in combination with cladribine (2-CdA), on CLL cells apoptosis in vitro: Preliminary results.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2022, Volume: 31, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bridged Bicyclo Compounds, Heterocyclic; Caspase 3; Caspase 9; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Sulfonamides

2022
Concurrent chronic lymphocytic leukemia/small lymphocytic lymphoma and hairy cell leukemia: clinical, pathologic and molecular features.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:13

    Topics: Cladribine; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell; Rituximab

2020
Clinical case: idelalisib-induced immunoglobulin flare.
    Immunopharmacology and immunotoxicology, 2017, Volume: 39, Issue:4

    Topics: Aged; Cladribine; Female; Humans; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Purines; Quinazolinones; Rituximab; Waldenstrom Macroglobulinemia

2017
Mechanisms of action of the anti-VEGF monoclonal antibody bevacizumab on chronic lymphocytic leukemia cells.
    Postepy higieny i medycyny doswiadczalnej (Online), 2013, Mar-01, Volume: 67

    Topics: Alemtuzumab; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevacizumab; Caspase 3; Caspase 9; Cladribine; Cyclophosphamide; Down-Regulation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Proteasome Inhibitors; Rituximab; Sirolimus; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vidarabine

2013
Cladribine Analogues via O⁶-(Benzotriazolyl) Derivatives of Guanine Nucleosides.
    Molecules (Basel, Switzerland), 2015, Oct-09, Volume: 20, Issue:10

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cladribine; Guanosine; Humans; Inhibitory Concentration 50; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Lymphoma, T-Cell; Organophosphorus Compounds; Primary Cell Culture; Structure-Activity Relationship

2015
Targeting DNA repair with aphidicolin sensitizes primary chronic lymphocytic leukemia cells to purine analogs.
    Oncotarget, 2016, Jun-21, Volume: 7, Issue:25

    Topics: Antineoplastic Agents; Aphidicolin; Apoptosis; Cladribine; DNA Damage; DNA Repair; Drug Synergism; Enzyme Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine

2016
Calorimetric study as a potential test for choosing treatment of B-cell chronic lymphocytic leukemia.
    Leukemia research, 2009, Volume: 33, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Calorimetry, Differential Scanning; Cell Survival; Cells, Cultured; Cladribine; Cyclophosphamide; DNA Damage; Drug Combinations; Drug Monitoring; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Myeloid Cell Leukemia Sequence 1 Protein; Phase Transition; Proto-Oncogene Proteins c-bcl-2; Vidarabine

2009
Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells.
    British journal of haematology, 2009, Volume: 144, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; Blotting, Western; Cladribine; Drug Synergism; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Microscopy, Confocal; Middle Aged; Reactive Oxygen Species; Tumor Cells, Cultured; Valproic Acid; Vidarabine

2009
Concomitant treatment with lamivudine renders cladribine inactive by inhibition of its phosphorylation.
    British journal of haematology, 2009, Volume: 144, Issue:1

    Topics: Antineoplastic Agents; Cladribine; Drug Interactions; Humans; Lamivudine; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Phosphorylation; Treatment Failure

2009
Activity of cladribine combined with cyclophosphamide in frontline therapy for chronic lymphocytic leukemia with 17p13.1/TP53 deletion: report from the Polish Adult Leukemia Group.
    Cancer, 2009, Jan-01, Volume: 115, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 17; Cladribine; Cyclophosphamide; Drug Administration Schedule; Female; Genes, p53; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Retrospective Studies; Sequence Deletion

2009
Drug induction apoptosis assay as predictive value of chemotherapy response in patients with B-cell chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2009, Volume: 50, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; B-Lymphocytes; Chlorambucil; Cladribine; Female; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Predictive Value of Tests; Prognosis; Time Factors; Tumor Cells, Cultured; Vidarabine

2009
Roscovitine triggers apoptosis in B-cell chronic lymphocytic leukemia cells with similar efficiency as combinations of conventional purine analogs with cyclophosphamide.
    Annals of the New York Academy of Sciences, 2009, Volume: 1171

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 9; Cell Survival; Cells, Cultured; Cladribine; Cyclin E; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclophosphamide; Drug Synergism; Female; Flow Cytometry; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Male; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Purines; Roscovitine; Vidarabine

2009
Impaired up-regulation of polo-like kinase 2 in B-cell chronic lymphocytic leukaemia lymphocytes resistant to fludarabine and 2-chlorodeoxyadenosine: a potential marker of defective damage response.
    British journal of haematology, 2009, Volume: 147, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Cell Death; Cladribine; Cohort Studies; DNA Damage; DNA, Neoplasm; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Up-Regulation; Vidarabine

2009
R-roscovitine (Seliciclib) affects CLL cells more strongly than combinations of fludarabine or cladribine with cyclophosphamide: Inhibition of CDK7 sensitizes leukemic cells to caspase-dependent apoptosis.
    Journal of cellular biochemistry, 2010, Jan-01, Volume: 109, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Cladribine; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Cyclophosphamide; Female; Humans; Immunoblotting; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Staging; Purines; Roscovitine; Vidarabine

2010
CD154 expression triggered by purine analogues in vitro: Correlation with treatment response and autoimmune events in chronic lymphocytic leukemia.
    Experimental hematology, 2010, Volume: 38, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Autoimmunity; CD40 Ligand; Cells, Cultured; Cladribine; Female; Flow Cytometry; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Outcome Assessment, Health Care; Prognosis; Vidarabine

2010
The efficacy and stem cell toxicity of cladribine and rituximab in the treatment of patients with chronic lymphocytic leukemia: are all purine analogs created equal?
    Leukemia & lymphoma, 2010, Volume: 51, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Clinical Trials, Phase II as Topic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplastic Stem Cells; Purines; Rituximab; Treatment Outcome

2010
Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells.
    Annals of hematology, 2010, Volume: 89, Issue:11

    Topics: ADP-ribosyl Cyclase 1; Anticholesteremic Agents; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; bcl-2-Associated X Protein; Caspase 3; Cell Cycle Proteins; Cladribine; DNA-Binding Proteins; Enzyme Activation; Histones; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Prognosis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Purines; Simvastatin; Tumor Cells, Cultured; Tumor Suppressor Proteins; Vidarabine; ZAP-70 Protein-Tyrosine Kinase

2010
Rituximab and subcutaneous cladribine in chronic lymphocytic leukemia for newly diagnosed and relapsed patients.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cladribine; Equilibrative Nucleoside Transporter 1; Female; Flow Cytometry; Humans; In Situ Hybridization, Fluorescence; Infusions, Subcutaneous; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Membrane Transport Proteins; Middle Aged; Neoplasm Recurrence, Local; Reverse Transcriptase Polymerase Chain Reaction; Rituximab; RNA, Messenger; Salvage Therapy; Survival Rate; Treatment Outcome

2010
Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia.
    Annals of hematology, 2011, Volume: 90, Issue:2

    Topics: ADP-ribosyl Cyclase 1; Adult; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; bcl-2-Associated X Protein; Caspase 3; Cell Cycle Proteins; Cladribine; DNA-Binding Proteins; Drug Therapy, Combination; Enzyme Activation; Histones; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Membrane Glycoproteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Purines; Resveratrol; Stilbenes; Tumor Suppressor Proteins; Vidarabine; ZAP-70 Protein-Tyrosine Kinase

2011
Effective treatment of leukemia cutis with combination of rituximab, cladribine, and cyclophosphamide in patient with B-cell chronic lymphocytic leukemia.
    Annals of hematology, 2011, Volume: 90, Issue:8

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Diagnostic Errors; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Remission Induction; Rituximab; Rosacea

2011
Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines.
    Biochemical pharmacology, 2011, Mar-01, Volume: 81, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cladribine; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Enzyme Activation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Proliferating Cell Nuclear Antigen; Proteasome Endopeptidase Complex; Purine Nucleosides; Tumor Suppressor Protein p53; Ubiquitination; Up-Regulation; Vidarabine

2011
Risk factors for Pneumocystis jirovecii pneumonia in patients with lymphoproliferative disorders.
    Clinical lymphoma, myeloma & leukemia, 2012, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Case-Control Studies; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Lymphoproliferative Disorders; Male; Middle Aged; Pneumocystis carinii; Pneumonia, Pneumocystis; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Vidarabine

2012
Can ex vivo evaluation (testing) predict the sensitivity of CLL cells to therapy with purine analogs in conjunction with an alkylating agent? A comparison of in vivo and ex vivo responses to treatment.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line; Cladribine; Cyclophosphamide; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Immunohistochemistry; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Purines; Roscovitine; Vidarabine

2012
Pure erythroid leukemia evolving from a therapy-related myelodysplastic syndrome secondary to treatment for chronic lymphocytic leukemia.
    American journal of hematology, 2013, Volume: 88, Issue:3

    Topics: Abnormal Karyotype; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Fatal Outcome; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Myelodysplastic Syndromes; Prednisone; Vidarabine; Vincristine

2013
Apoptotic gene expression under influence of fludarabine and cladribine in chronic lymphocytic leukemia-microarray study.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Cladribine; DNA, Complementary; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Transcriptome; Tumor Cells, Cultured; Vidarabine

2012
Fludarabine and cladribine induce changes in surface proteins on human B-lymphoid cell lines involved with apoptosis, cell survival, and antitumor immunity.
    Journal of proteome research, 2012, Sep-07, Volume: 11, Issue:9

    Topics: Antigens, CD; Apoptosis; B-Lymphocytes; Burkitt Lymphoma; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Survival; Cladribine; Drug Resistance, Neoplasm; Flow Cytometry; Glycoproteins; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Proteins; Reproducibility of Results; Signal Transduction; Up-Regulation; Vidarabine

2012
Effects of Toll-like receptor 7 and Toll-like receptor 9 signaling stimulators and inhibitors on chronic lymphocytic leukemia cells ex vivo and their interactions with cladribine.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:6

    Topics: Aged; Antigens, CD; Antineoplastic Agents; Cladribine; Cytokines; DNA; Drug Interactions; Female; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Ligands; Male; Middle Aged; Signal Transduction; Toll-Like Receptor 7; Toll-Like Receptor 9; Tumor Cells, Cultured

2013
Toward personalized therapy for chronic lymphocytic leukemia: DSC and cDNA microarray assessment of two cases.
    Cancer biology & therapy, 2013, Volume: 14, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Calorimetry, Differential Scanning; Cell Nucleus; Cell Survival; Cladribine; Cyclophosphamide; Drug Resistance, Neoplasm; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Precision Medicine; Proto-Oncogene Proteins c-bcl-2; Rituximab; Transcriptome; Treatment Outcome; Tumor Cells, Cultured

2013
Bendamustine in the treatment of chronic lymphocytic leukemia: results and future perspectives.
    Seminars in oncology, 2002, Volume: 29, Issue:4 Suppl 13

    Topics: Aged; Aged, 80 and over; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bendamustine Hydrochloride; Cladribine; Drug Administration Schedule; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrogen Mustard Compounds; Remission Induction; Rituximab; Salvage Therapy; Vidarabine

2002
Re-treatment with cladribine-based regimens in relapsed patients with B-cell chronic lymphocytic leukemia. Efficacy and toxicity in comparison with previous treatment.
    European journal of haematology, 2002, Volume: 69, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Disease-Free Survival; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitoxantrone; Prednisone; Recurrence; Survival Analysis; Treatment Outcome

2002
Cladribine induces immunophenotypical changes in bone marrow mast cells from mastocytosis. Report of a case of mastocytosis associated with a lymphoplasmacytic lymphoma.
    Leukemia research, 2002, Volume: 26, Issue:11

    Topics: Aged; Antigens, CD; Antineoplastic Agents; Bone Marrow Cells; Cladribine; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Mast Cells; Mastocytosis

2002
Successful treatment of leukaemia cutis with cladribine in a patient with B-cell chronic lymphocytic leukaemia.
    The British journal of dermatology, 2002, Volume: 147, Issue:4

    Topics: Aged; Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemic Infiltration; Male; Skin

2002
Comparison of cytotoxicity of 2-chloro- 2'-arabino-fluoro-2'-deoxyadenosine (clofarabine) with cladribine in mononuclear cells from patients with acute myeloid and chronic lymphocytic leukemia.
    Haematologica, 2003, Volume: 88, Issue:3

    Topics: Acute Disease; Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Arabinonucleosides; Cell Survival; Cladribine; Clofarabine; Drug Evaluation; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukocytes, Mononuclear; Male; Middle Aged

2003
Hodgkin's type of Richter's syndrome in familial chronic lymphocytic leukemia treated with cladribine and cyclophosphamide.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:5

    Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cladribine; Cyclophosphamide; Family Health; Herpesvirus 4, Human; Hodgkin Disease; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymph Nodes; Male; Middle Aged; Neoplasms, Second Primary; Syndrome

2003
Second malignancies and Richter's syndrome in patients with chronic lymphocytic leukaemia treated with cladribine.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Doxorubicin; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Male; Middle Aged; Neoplasms, Second Primary; Prednisone; Retrospective Studies; Syndrome; Vincristine

2004
Metabolic response patterns of nucleotides in B-cell chronic lymphocytic leukaemias to cladribine, fludarabine and deoxycoformycin.
    Leukemia research, 2004, Volume: 28, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Humans; Ionomycin; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Nucleotides; Pentostatin; Prognosis; Tumor Cells, Cultured; Vidarabine

2004
Cutaneous adverse reaction to 2-chlorodeoxyadenosine with histological flame figures in patients with chronic lymphocytic leukaemia.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2004, Volume: 18, Issue:5

    Topics: Aged; Antineoplastic Agents; Cladribine; Diagnosis, Differential; Drug Eruptions; Exanthema; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged

2004
Richter's syndrome in the brain first manifested as an ischaemic stroke.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:6

    Topics: Brain; Brain Ischemia; Brain Neoplasms; Cell Transformation, Neoplastic; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Middle Aged; Syndrome

2004
VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia.
    European journal of haematology, 2004, Volume: 73, Issue:6

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cladribine; Cyclophosphamide; Cytarabine; DNA Mutational Analysis; Doxorubicin; Drug Resistance, Neoplasm; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Genes, Immunoglobulin; Humans; Idarubicin; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Leukemia, Lymphocytic, Chronic, B-Cell; Life Tables; Melphalan; Prednisolone; Survival Analysis; Vidarabine; Vincristine

2004
Effects of 2-chloro-2'-deoxyadenosine on the cell cycle in the human leukemia EHEB cell line.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cladribine; Cyclin-Dependent Kinase Inhibitor p21; Deoxycytidine Kinase; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; G1 Phase; Humans; Inhibitory Concentration 50; Leukemia, Lymphocytic, Chronic, B-Cell; Models, Biological; Phosphorylation; S Phase; Time Factors

2004
2-Chlorodeoxyadenosine alone and in combination with cyclophosphamide and mitoxantrone induce apoptosis in B chronic lymphocytic leukemia cells in vivo.
    Cancer detection and prevention, 2004, Volume: 28, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Cladribine; Cyclophosphamide; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Male; Middle Aged; Mitoxantrone

2004
The influence of chemotherapy on bone marrow in patients with chronic lymphocytic leukaemia.
    Folia morphologica, 2004, Volume: 63, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Biopsy; Bone Marrow; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm, Residual; Vidarabine

2004
The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells.
    Blood, 2005, Jul-15, Volume: 106, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Caspases; Chlorambucil; Cladribine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; In Vitro Techniques; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Lignans; Magnolia; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phytotherapy; Proto-Oncogene Proteins c-bcl-2; Vidarabine

2005
In vitro cytotoxic effect of proteasome inhibitor bortezomib in combination with purine nucleoside analogues on chronic lymphocytic leukaemia cells.
    European journal of haematology, 2005, Volume: 74, Issue:5

    Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Survival; Cladribine; Dose-Response Relationship, Drug; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Proteasome Inhibitors; Pyrazines; Tumor Cells, Cultured

2005
Merkel cell carcinoma in a patient with B-cell chronic lymphocytic leukemia treated with cladribine and rituximab.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:6

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Carcinoma, Merkel Cell; Cladribine; Female; Humans; Immunosuppressive Agents; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphatic Metastasis; Middle Aged; Remission Induction; Rituximab; Skin Neoplasms; Treatment Outcome

2005
In vitro sensitivity of B-cell chronic lymphocytic leukemia to cladribine and its combinations with mafosfamide and/or mitoxantrone.
    Oncology reports, 2006, Volume: 16, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X Protein; Blotting, Western; Caspases; Cladribine; Cyclophosphamide; DNA Fragmentation; Female; Humans; In Vitro Techniques; Lamin Type B; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Mitochondria; Mitoxantrone; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2006
Pharmacological inhibition of the MAPK/ERK pathway increases sensitivity to 2-chloro-2'-deoxyadenosine (CdA) in the B-cell leukemia cell line EHEB.
    Biochemical pharmacology, 2007, Feb-01, Volume: 73, Issue:3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cladribine; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; MAP Kinase Signaling System; Phosphorylation; Protein Kinase Inhibitors

2007
Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:12

    Topics: Alemtuzumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cladribine; Etodolac; Humans; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Purines; Rituximab; Spectrometry, Fluorescence; Vidarabine

2006
Influence of cladribine alone and in combination with cyclophosphamide or cyclophosphamide and mitoxantrone on bone marrow angiogenesis in chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:5

    Topics: Adult; Aged; Bone Marrow Cells; Cladribine; Cyclophosphamide; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Microcirculation; Middle Aged; Mitoxantrone; Neovascularization, Pathologic; Treatment Outcome

2007
Chromosomal translocations independently predict treatment failure, treatment-free survival and overall survival in B-cell chronic lymphocytic leukemia patients treated with cladribine.
    Leukemia, 2007, Volume: 21, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chromosome Aberrations; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 17; Cladribine; Female; Humans; In Situ Hybridization, Fluorescence; Interphase; Karyotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mutation; Prognosis; Risk Factors; Survival Rate; Translocation, Genetic; Treatment Failure; Tumor Suppressor Protein p53

2007
t(14;18)(q32;q21)-bearing pleural MALT lymphoma with IgM paraproteinemia: value of detection of specific cytogenetic abnormalities in the differential diagnosis of MALT lymphoma and lymphoplasmacytic lymphoma.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:4

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Caspases; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; Cladribine; Diagnosis, Differential; Diagnostic Errors; Female; Humans; Immunoglobulin Heavy Chains; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell, Marginal Zone; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; Paraproteins; Pleural Neoplasms; Remission Induction; Rituximab; Translocation, Genetic

2007
Cannabinoid receptors expression in bone marrow trephine biopsy of chronic lymphocytic leukaemia patients treated with purine analogues.
    Experimental oncology, 2007, Volume: 29, Issue:3

    Topics: Antineoplastic Agents; B-Lymphocytes; Biopsy; Bone Marrow Cells; Cladribine; Flow Cytometry; Humans; Immunohistochemistry; Leukemia, Lymphocytic, Chronic, B-Cell; Purines; Receptors, Cannabinoid; Vidarabine

2007
Comparison of antitumor activities of 2-chlorodeoxyadenosine and 9-beta-arabinosyl-2-fluoroadenine in chronic lymphocytic leukemia and marrow cells in vitro.
    Leukemia, 1995, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Biological Transport; Bone Marrow; Cell Survival; Cells, Cultured; Chlorambucil; Cladribine; Drug Administration Schedule; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine

1995
Intracellular pharmacokinetics of 2-chlorodeoxyadenosine in leukemia cells from patients with chronic lymphocytic leukemia.
    Leukemia, 1995, Volume: 9, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biological Transport; Cladribine; Female; Half-Life; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Thioinosine

1995
Molecular complete response in a patient with chronic lymphocytic leukaemia treated with 2-chlorodeoxyadenosine.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:4

    Topics: Blotting, Southern; Cladribine; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Polymerase Chain Reaction

1995
Increased ratio between deoxycytidine kinase and thymidine kinase 2 in CLL lymphocytes compared to normal lymphocytes.
    Leukemia research, 1995, Volume: 19, Issue:7

    Topics: Cells, Cultured; Cladribine; Deoxycytidine Kinase; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Phosphorylation; Substrate Specificity; Thymidine Kinase; Tumor Cells, Cultured

1995
Modulation of purine analogs- and chlorambucil-induced cytotoxicity by alpha-interferon and interleukin-2 in chronic lymphocytic leukemia.
    Leukemia, 1995, Volume: 9, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Chlorambucil; Cladribine; Dose-Response Relationship, Drug; Humans; Interferon-alpha; Interleukin-1; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Tumor Necrosis Factor-alpha; Vidarabine

1995
Acute onset of severe autoimmune hemolytic anemia after treatment with 2-chlorodeoxyadenosine for chronic lymphocytic leukemia.
    American journal of hematology, 1995, Volume: 48, Issue:4

    Topics: Anemia, Hemolytic, Autoimmune; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged

1995
Expression of deoxycytidine kinase and phosphorylation of 2-chlorodeoxyadenosine in human normal and tumour cells and tissues.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:2

    Topics: Blotting, Western; Cladribine; Colonic Neoplasms; Deoxycytidine Kinase; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Phosphorylation; Sarcoma; Stomach Neoplasms; Tissue Distribution; Tumor Cells, Cultured

1995
[Hematologic remission and disappearance of hemolytic anemia in chronic lymphocytic leukemia after therapy with 2-chlorodeoxyadenosine (2-CDA)].
    Acta haematologica Polonica, 1993, Volume: 24, Issue:3

    Topics: Anemia, Hemolytic; Autoimmune Diseases; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Male; Middle Aged; Remission Induction

1993
Lack of effect of 2-chlorodeoxyadenosine therapy in patients with chronic lymphocytic leukemia refractory to fludarabine therapy.
    The New England journal of medicine, 1994, Feb-03, Volume: 330, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neutropenia; Remission Induction; Thrombocytopenia; Vidarabine

1994
[Pneumocystis carinii pneumonia during therapy with 2-chlorodeoxyadenosine (2-CDA)].
    Schweizerische medizinische Wochenschrift, 1994, Jan-11, Volume: 124, Issue:1-2

    Topics: Aged; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pneumonia, Pneumocystis

1994
2-Chlorodeoxyadenosine therapy in chronic lymphocytic leukemia.
    The New England journal of medicine, 1994, Jun-23, Volume: 330, Issue:25

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine

1994
2-Chlorodeoxyadenosine therapy in chronic lymphocytic leukemia.
    The New England journal of medicine, 1994, Jun-23, Volume: 330, Issue:25

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine

1994
2-Chlorodeoxyadenosine treatment of patients with chronic lymphocytic leukaemia associated with autoimmune haemolysis.
    Acta haematologica Polonica, 1994, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Remission Induction; Treatment Outcome

1994
In vitro activity of 2-chlorodeoxyadenosine (CdA) in primary cultures of human haematological and solid tumours.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:7

    Topics: Adrenocortical Carcinoma; Breast Neoplasms; Cladribine; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lung Neoplasms; Neoplasms; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

1994
Secondary neoplasms in two patients treated with purine analogues.
    Nouvelle revue francaise d'hematologie, 1994, Volume: 36, Issue:4

    Topics: Acute Disease; Aged; Cladribine; Female; Humans; Immunocompromised Host; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Melanoma; Neoplasms, Second Primary; Skin Neoplasms; Vidarabine; Waldenstrom Macroglobulinemia

1994
Analysis of 2-chloro-2'-deoxyadenosine in human blood plasma and urine by high-performance liquid chromatography using solid-phase extraction.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:4

    Topics: Chromatography, High Pressure Liquid; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged

1994
Apoptosis induction with three nucleoside analogs on freshly isolated B-chronic lymphocytic leukemia cells.
    American journal of hematology, 1994, Volume: 47, Issue:4

    Topics: Aged; Apoptosis; Cladribine; DNA Damage; Female; Humans; In Vitro Techniques; Interferon-alpha; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Pentostatin; Tumor Cells, Cultured; Vidarabine

1994
Phosphorylation of 2-chlorodeoxyadenosine (CdA) in extracts of peripheral blood mononuclear cells of leukaemic patients.
    British journal of haematology, 1994, Volume: 87, Issue:4

    Topics: Cladribine; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic, T-Cell; Leukocytes, Mononuclear; Phosphorylation

1994
Complete remission of B-cell chronic lymphocytic leukaemia after oral cladribine.
    Lancet (London, England), 1993, Jan-02, Volume: 341, Issue:8836

    Topics: Administration, Oral; Adult; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Remission Induction

1993
Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine.
    Blood, 1993, Jan-01, Volume: 81, Issue:1

    Topics: Adenosine Triphosphate; Apoptosis; Cladribine; Cycloheximide; Dactinomycin; DNA, Neoplasm; Egtazic Acid; Guanosine Triphosphate; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Microscopy, Electron; Puromycin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uridine Triphosphate; Vidarabine

1993
Relationship of deoxycytidine kinase and cytoplasmic 5'-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine.
    Blood, 1993, Feb-01, Volume: 81, Issue:3

    Topics: 5'-Nucleotidase; Aged; Antigens, CD; Cladribine; Cytoplasm; Deoxycytidine Kinase; False Positive Reactions; Female; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prognosis; Tumor Cells, Cultured

1993
2-Chlorodeoxyadenosine for patients with B-cell chronic lymphocytic leukemia resistant to fludarabine.
    The New England journal of medicine, 1993, Mar-18, Volume: 328, Issue:11

    Topics: Antineoplastic Agents; Cladribine; Drug Resistance; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Vidarabine

1993
Listeriosis after 2-chlorodeoxyadenosine treatment.
    The New England journal of medicine, 1993, Mar-18, Volume: 328, Issue:11

    Topics: Aged; Antineoplastic Agents; Cladribine; Drug Resistance; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Listeriosis; Vidarabine

1993
High complete remission rate from 2-chloro-2'-deoxyadenosine in previously treated patients with B-cell chronic lymphocytic leukemia: response predicted by rapid decrease of blood lymphocyte count.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bone Marrow; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Lymphocytes; Male; Middle Aged; Recurrence; Remission Induction; Survival Rate

1993
Brief report: tumor lysis syndrome following treatment with 2-chlorodeoxyadenosine for refractory chronic lymphocytic leukemia.
    The New England journal of medicine, 1993, Nov-18, Volume: 329, Issue:21

    Topics: Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphatic Diseases; Male; Middle Aged; Tumor Lysis Syndrome

1993
Nucleoside transporters, bcl-2 and apoptosis in CLL cells exposed to nucleoside analogues in vitro.
    European journal of haematology, 1996, Volume: 56, Issue:4

    Topics: Antigens, CD19; Apoptosis; B-Lymphocytes; Carrier Proteins; CD5 Antigens; Cladribine; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Proteins; Neoplasm Proteins; Nucleoside Transport Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; S Phase; Tumor Cells, Cultured; Vidarabine

1996
Infectious complications after 2-chlorodeoxyadenosine therapy.
    European journal of haematology, 1996, Volume: 56, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cladribine; Cohort Studies; Disease Susceptibility; Female; Fever; Hematologic Diseases; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Incidence; Infections; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Lymphoma, Non-Hodgkin; Male; Middle Aged; Retrospective Studies; Risk Factors; Waldenstrom Macroglobulinemia

1996
Delayed reactivation of hepatitis B infection after cladribine.
    Lancet (London, England), 1996, Jul-13, Volume: 348, Issue:9020

    Topics: Aged; Cladribine; Hepatitis B; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Recurrence

1996
2-Chlorodeoxyadenosine (2-CdA) in chronic lymphocytic leukemia refractory to fludarabine?
    Leukemia, 1996, Volume: 10, Issue:7

    Topics: Antineoplastic Agents; Cladribine; Drug Resistance, Neoplasm; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Vidarabine

1996
2-Chlorodeoxyadenosine (2-CdA) in the treatment of patients with relapsed chronic lymphocytic leukemia.
    Archivum immunologiae et therapiae experimentalis, 1995, Volume: 43, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Agents; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Recurrence

1995
Long-term survival following cladribine (2-chlorodeoxyadenosine) therapy in previously treated patients with chronic lymphocytic leukemia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cell Count; Cladribine; Combined Modality Therapy; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Opportunistic Infections; Remission Induction; Retreatment; Survival Rate; Treatment Outcome; Vidarabine

1996
Fludarabine, as well as 2-chlorodeoxyadenosine, can induce eosinophilia during treatment of lymphoid malignancies.
    British journal of haematology, 1996, Volume: 94, Issue:4

    Topics: Aged; Antineoplastic Agents; Cladribine; Eosinophilia; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphatic Diseases; Lymphoma, Follicular; Male; Middle Aged; Retrospective Studies; Vidarabine

1996
Determination of 2-chloro-2'-deoxyadenosine nucleotides in leukemic cells by ion-pair high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1996, Jun-28, Volume: 682, Issue:1

    Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Circadian Rhythm; Cladribine; Drug Stability; Half-Life; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Temperature; Time Factors; Tumor Cells, Cultured

1996
The induction of p53 and WAF1/CIP1 in chronic lymphocytic leukemia cells treated with 2-chlorodeoxyadenosine.
    Journal of molecular medicine (Berlin, Germany), 1996, Volume: 74, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; B-Lymphocytes; Cladribine; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Gene Expression; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1996
High response rates with short infusional 2-chlorodeoxyadenosine in de novo and relapsed low-grade lymphoma. Australian and New Zealand Lymphoma Study Group.
    British journal of haematology, 1996, Volume: 95, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Cladribine; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukopenia; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Male; Middle Aged; Opportunistic Infections; Recurrence; Survival Analysis; Thrombocytopenia; Treatment Outcome

1996
In vitro cytotoxicity of 2-chlorodeoxyadenosine and chlorambucil in chronic lymphocytic leukemia.
    Leukemia, 1996, Volume: 10, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cells, Cultured; Chlorambucil; Cladribine; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Tritium; Tumor Cells, Cultured

1996
Myelodysplasia following treatment of chronic lymphocytic leukemia (CLL) with 2-chlorodeoxyadenosine (2-CdA)
    Leukemia, 1997, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Chromosomes, Human, Pair 7; Cladribine; Fatal Outcome; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Monosomy; Myelodysplastic Syndromes

1997
Occurrence of myeloma in a chronic lymphocytic leukemia patients after response to differentiation therapy with interleukin-4.
    Leukemia & lymphoma, 1996, Volume: 23, Issue:5-6

    Topics: Antineoplastic Agents; Cell Differentiation; Cladribine; Humans; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Multiple Myeloma

1996
2-Chlorodeoxyadenosine inhibits activity of adenosine deaminase and S-adenosylhomocysteine hydrolase in patients with chronic lymphocytic leukaemia.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:1

    Topics: Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cladribine; Humans; Hydrolases; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged

1997
Autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia treated with 2-chlorodeoxyadenosine (cladribine).
    European journal of haematology, 1997, Volume: 58, Issue:2

    Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Antigens, CD; Antineoplastic Agents; B-Lymphocytes; Cladribine; Coombs Test; Female; Hemolysis; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Retrospective Studies

1997
Induction of apoptosis by 2-chlorodeoxyadenosine in B cell chronic lymphocytic leukemia.
    Leukemia, 1997, Volume: 11, Issue:8

    Topics: Adult; Aged; Apoptosis; Cladribine; DNA Fragmentation; DNA, Neoplasm; Female; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Tumor Cells, Cultured

1997
2-chlorodeoxyadenosine (cladribine) induced allergic cutaneous reactions with eosinophilia in a patient with B-cell chronic lymphocytic leukemia.
    Journal of medicine, 1997, Volume: 28, Issue:3-4

    Topics: Aged; Antineoplastic Agents; Cladribine; Drug Eruptions; Eosinophilia; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male

1997
Sequential treatment of human chronic lymphocytic leukemia with bryostatin 1 followed by 2-chlorodeoxyadenosine: preclinical studies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

    Topics: Acid Phosphatase; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bryostatins; Cell Division; Cladribine; DNA, Neoplasm; Drug Administration Schedule; Drug Screening Assays, Antitumor; Humans; Lactones; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lipid Metabolism; Macrolides; Male; Mice; Mice, SCID; Neoplasm Proteins; Neoplasm Transplantation; Spectroscopy, Fourier Transform Infrared; Transplantation, Heterologous; Tumor Cells, Cultured

1998
More on purine analog-induced apoptosis in B cell chronic lymphocytic leukemia.
    Leukemia, 1998, Volume: 12, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Tumor Cells, Cultured; Vidarabine Phosphate

1998
Relationship between cladribine (CdA) plasma, intracellular CdA-5'-triphosphate (CdATP) concentration, deoxycytidine kinase (dCK), and chemotherapeutic activity in chronic lymphocytic leukemia (CLL).
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Antineoplastic Agents; Cladribine; Deoxycytidine Kinase; Female; Half-Life; Humans; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Male; Treatment Outcome

1998
The effect of 2-h infusion of 2-chlorodeoxyadenosine (cladribine) with prednisone in previously untreated B-cell chronic lymphocytic leukaemia.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Female; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prednisone; Retrospective Studies; Survival Analysis

1997
Similarities between the sensitivity to 2-chlorodeoxyadenosine of lymphocytes from CLL patients and bryostatin 1-treated WSU-CLL cells: an infrared spectroscopic study.
    Cancer letters, 1998, May-15, Volume: 127, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Agents; Bryostatins; Cladribine; Drug Resistance; Female; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Macrolides; Male; Middle Aged; Spectrophotometry, Infrared; Tumor Cells, Cultured

1998
In vitro chemosensitivity of chronic lymphocytic leukaemia to purine analogues--correlation with clinical course.
    Leukemia, 1998, Volume: 12, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Cladribine; DNA Nucleotidylexotransferase; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Phenotype; Proto-Oncogene Proteins c-bcl-2; Vidarabine

1998
Paradoxical immunologic effects of 2-CdA therapy: comment on the article by Davis et al.
    Arthritis and rheumatism, 1998, Volume: 41, Issue:9

    Topics: Anemia, Hemolytic; Antibodies, Antinuclear; Arthritis, Rheumatoid; Cladribine; Female; Humans; Immune System Diseases; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Lupus Nephritis; Lymphopenia; Male; Middle Aged

1998
Chlorambucil synergizes with purine analogs in inducing in vitro cytotoxicity in B-cell chronic lymphocytic leukemia.
    Haematologica, 1998, Volume: 83, Issue:8

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Chlorambucil; Cladribine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplastic Stem Cells; Tumor Cells, Cultured; Vidarabine

1998
Potentiation of 2-chlorodeoxyadenosine activity by bryostatin 1 in the resistant chronic lymphocytic leukemia cell line (WSU-CLL): association with increased ratios of dCK/5'-NT and Bax/Bcl-2.
    Biological chemistry, 1998, Volume: 379, Issue:10

    Topics: 5'-Nucleotidase; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bryostatins; Cell Division; Cladribine; Deoxycytidine Kinase; Drug Synergism; Female; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Mice; Mice, Inbred ICR; Mice, SCID; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
In vitro modulation of bcl-2 protein expression, drug-induced apoptosis and cytotoxicity by interleukin-10 in chronic lymphocytic leukemia.
    Haematologica, 1998, Volume: 83, Issue:11

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Cladribine; Drug Interactions; Drug Screening Assays, Antitumor; Gene Expression Regulation, Leukemic; Humans; Interleukin-10; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Vidarabine

1998
Long term follow-up and late complications of 2-chlorodeoxyadenosine in previously treated, advanced, indolent non-Hodgkin's lymphoma.
    Cancer, 1999, Jan-01, Volume: 85, Issue:1

    Topics: Antineoplastic Agents; Cladribine; Female; Follow-Up Studies; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Remission Induction

1999
Chemosensitivity in vitro to 2-chlorodeoxyadenosine and 9-beta-D-arabinofuranosyl-2-fluoroadenine in previously unexposed cases of chronic lymphocytic leukemia.
    Leukemia research, 1999, Volume: 23, Issue:3

    Topics: Antineoplastic Agents; Cells, Cultured; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Vidarabine

1999
Cladribine with cyclophosphamide and prednisone in the management of low-grade lymphoproliferative malignancies.
    British journal of cancer, 1999, Volume: 79, Issue:7-8

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphamide; Drug Administration Schedule; Feasibility Studies; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prednisone; Waldenstrom Macroglobulinemia

1999
2-Chlorodeoxyadenosine (Cladribine) in the treatment of patients with chronic lymphocytic leukemia 55 years old and younger.
    Leukemia, 1999, Volume: 13, Issue:4

    Topics: Adult; Alopecia; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Cladribine; Cyclophosphamide; Doxorubicin; Drug Eruptions; Drug Resistance, Neoplasm; Female; Fever; Hematologic Diseases; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prednisone; Recurrence; Remission Induction; Salvage Therapy; Treatment Outcome; Vincristine

1999
Use of image analysis and immunostaining of bone marrow trephine biopsy specimens to quantify residual disease in patients with B-cell chronic lymphocytic leukemia.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1999, Volume: 12, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; B-Lymphocytes; Biopsy; Bone Marrow; Bone Marrow Examination; Cladribine; Female; Flow Cytometry; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm, Residual; Proto-Oncogene Proteins c-bcl-2; Remission Induction

1999
Potentiation of antitumor effects of cyclophosphamide derivatives in B-chronic lymphocytic leukemia cells by 2-chloro-2'-deoxyadenosine.
    Leukemia, 1999, Volume: 13, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cladribine; Cyclophosphamide; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Time Factors; Tritium; Tumor Cells, Cultured

1999
Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:9

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Cladribine; Clofarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Phosphorylation; Recombinant Proteins; Tumor Cells, Cultured

1999
The effect of p53 dysfunction on purine analogue cytotoxicity in chronic lymphocytic leukaemia.
    British journal of haematology, 1999, Volume: 106, Issue:4

    Topics: Antineoplastic Agents; Cell Survival; Cladribine; Genes, p53; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Tumor Cells, Cultured; Vidarabine

1999
Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:8

    Topics: Aged; Antineoplastic Agents; Cladribine; Female; Follow-Up Studies; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasms, Second Primary; Pentostatin; Vidarabine

1999
Bryostatin 1-induced modulation of nucleoside transporters and 2-chlorodeoxyadenosine influx in WSU-CLL cells.
    International journal of molecular medicine, 2000, Volume: 5, Issue:4

    Topics: Aged; Antineoplastic Agents; Biological Transport, Active; Bryostatins; Carrier Proteins; Cladribine; Deoxycytidine Kinase; Dipyridamole; Down-Regulation; Drug Resistance, Neoplasm; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; Membrane Proteins; Nucleoside Transport Proteins; Phosphorylation; Thioinosine; Tumor Cells, Cultured; Vidarabine

2000
Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Cladribine; Comorbidity; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Epirubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Methylprednisolone; Middle Aged; Neoplastic Stem Cells; Palliative Care; Pentostatin; Prednisolone; Prognosis; Staining and Labeling; Tumor Cells, Cultured; Vidarabine; Vincristine

2000
Sequential treatment of a resistant chronic lymphocytic leukemia patient with bryostatin 1 followed by 2-chlorodeoxyadenosine: case report.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:4

    Topics: 5'-Nucleotidase; Aged; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X Protein; Blotting, Western; Bryostatins; Cell Adhesion Molecules; Cladribine; Clinical Trials, Phase I as Topic; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Integrin alphaXbeta2; Lactones; Lectins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Macrolides; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sialic Acid Binding Ig-like Lectin 2

2000
Serum levels of IL-6 type cytokines and soluble IL-6 receptors in active B-cell chronic lymphocytic leukemia and in cladribine induced remission.
    Mediators of inflammation, 1999, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Cladribine; Cytokine Receptor gp130; Female; Growth Inhibitors; Humans; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphokines; Male; Membrane Glycoproteins; Middle Aged; Oncostatin M; Peptides; Receptors, Interleukin-6; Remission Induction; Solubility

1999
Calcium antagonists potentiate P-glycoprotein-independent anticancer drugs in chronic lymphocytic leukemia cells in vitro.
    Haematologica, 2000, Volume: 85, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; B-Lymphocytes; Calcium; Calcium Channel Blockers; Calcium Signaling; Chlorambucil; Cisplatin; Cladribine; Cyclosporine; DNA Fragmentation; Doxorubicin; Drug Synergism; Female; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Nifedipine; Prednisolone; Tumor Cells, Cultured; Verapamil; Vidarabine; Vincristine

2000
Role of poly(ADP-ribosyl)ation in the killing of chronic lymphocytic leukemia cells by purine analogues.
    Cancer research, 2000, Aug-01, Volume: 60, Issue:15

    Topics: Antineoplastic Agents; Benzamides; Cell Death; Cell Membrane; Cell Size; Cladribine; DNA Fragmentation; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tumor Suppressor Protein p53; Vidarabine

2000
Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.
    Blood, 2000, Nov-15, Volume: 96, Issue:10

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Arabinonucleosides; B-Lymphocytes; Cell Survival; Cladribine; Clofarabine; Comet Assay; Deoxyadenosines; DNA Damage; DNA, Mitochondrial; Humans; Immunohistochemistry; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Potentials; Microinjections; Mitochondria; Time Factors; Tumor Cells, Cultured; Vidarabine

2000
Pure red cell aplasia in patients with chronic lymphocytic leukaemia treated with cladribine.
    British journal of haematology, 2001, Volume: 112, Issue:4

    Topics: Aged; Cladribine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Red-Cell Aplasia, Pure

2001
Does intensive treatment with high dose chlorambucil and prednisone as first line and cladribine as second line influence the survival of the patients with chronic lymphocytic leukemia?
    Leukemia & lymphoma, 2001, Volume: 41, Issue:5-6

    Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Chlorambucil; Cladribine; Cohort Studies; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prednisone; Recurrence; Retrospective Studies; Survival Rate

2001
Richter's syndrome following cladribine therapy for chronic lymphocytic leukemia first manifested as pathologic fracture of the femur.
    Leukemia & lymphoma, 2001, Volume: 42, Issue:4

    Topics: Aged; Bone Marrow; Cell Transformation, Neoplastic; Cladribine; Femoral Fractures; Humans; Karyotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Lymph Nodes; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Neoplasms, Second Primary; Radionuclide Imaging; Syndrome

2001
Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement, and caspases.
    Haematologica, 2002, Volume: 87, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Bendamustine Hydrochloride; Burkitt Lymphoma; Caspase 7; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cladribine; Complement Activation; Complement System Proteins; Cysteine Proteinase Inhibitors; Doxorubicin; Drug Synergism; Gene Expression Regulation, Leukemic; Gene Expression Regulation, Neoplastic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell; Lymphoma, Follicular; Mitoxantrone; Neoplasm Proteins; Nitrogen Mustard Compounds; Oligopeptides; Rabbits; Rituximab; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
2-Chloro-2'-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes.
    Leukemia, 2002, Volume: 16, Issue:1

    Topics: Alkylating Agents; Alkylation; Antimetabolites, Antineoplastic; Apoptosis; B-Lymphocytes; Caspase 3; Caspases; Cladribine; Depression, Chemical; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Humans; Hydroxyurea; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Proteins; Neoplastic Stem Cells; Phosphorylation; Prodrugs; Radiation Tolerance; Radiation-Sensitizing Agents; Thymidine; Tumor Cells, Cultured; Ultraviolet Rays

2002
Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia.
    Leukemia, 2002, Volume: 16, Issue:6

    Topics: Aged; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Chlorambucil; Cladribine; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Glucocorticoids; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Vidarabine

2002
Cladribine decreases the level of angiogenic factors in patients with chronic lymphocytic leukemia.
    Neoplasma, 2002, Volume: 49, Issue:3

    Topics: Aged; Angiogenesis Inducing Agents; Antineoplastic Agents; Cladribine; Female; Fibroblast Growth Factor 2; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Transforming Growth Factor beta

2002
Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Apr-01, Volume: 89, Issue:7

    Topics: 2-Chloroadenosine; Adenine Nucleotides; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Cell Death; Cladribine; Clofarabine; Deoxyadenosines; DNA; DNA Damage; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Mice; Mice, SCID; Monocytes

1992
Pentostatin and 2-chlorodeoxyadenosine for hairy-cell leukemia.
    The Medical letter on drugs and therapeutics, 1992, Sep-18, Volume: 34, Issue:879

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Pentostatin; Vidarabine

1992
New drugs in the treatment of chronic lymphocytic leukemia.
    Leukemia, 1992, Volume: 6 Suppl 4

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine

1992
2-Chlorodeoxyadenosine chemotherapy triggers programmed cell death in normal and malignant lymphocytes.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: 2-Chloroadenosine; Cell Death; Cladribine; Deoxyadenosines; DNA; DNA Damage; Humans; In Vitro Techniques; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Nucleosomes; Reference Values

1991