Page last updated: 2024-08-22

cladribine and Acute Lymphoid Leukemia

cladribine has been researched along with Acute Lymphoid Leukemia in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (54.55)18.2507
2000's4 (36.36)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goto, H; Goto, S; Yokosuka, T1
Badowska, W; Balcerska, A; Balwierz, W; Czyzewski, K; Debski, R; Juraszewska, E; Konatkowska, B; Kowalczyk, J; Krawczuk-Rybak, M; Kuzmicz, M; Malinowska, I; Matysiak, M; Olejnik, I; Ploszynska, A; Sońta-Jakimczyk, D; Stanczak, E; Stefaniak, J; Styczynski, J; Szczepanski, T; Wachowiak, J; Wieczorek, M; Wysocki, M1
Inanami, O; Kuwabara, M; Matsuda, A; Ohta, T; Takahashi, E1
Blakley, RL; Crom, WR; Kearns, CM; Santana, VM1
Beck, WT; Behm, FG; Blakley, RL; Campana, D; Coustan-Smith, E; Kumagai, M; Manabe, A; Raimondi, SC; Santana, VM1
Csoka, K; de la Torre, M; Fridborg, H; Kristensen, J; Larsson, R; Liliemark, J; Nygren, P1
Cohen, JD; Katz, TB; Marcel, PD; Strock, DJ; Teik, JE1
Gati, WP; Paterson, AR; Wright, AM1
Akabutu, JJ; Gati, WP; Grundy, PE; Paterson, AR; Sowa, B; Wright, AM1
Blakley, RL; Crom, W; Kearns, C; Mirro, J; Santana, VM; Schell, MJ1
Blakley, RL; Cherrie, J; Harwood, FC; Kalwinsky, D; Mirro, J; Santana, VM; Schell, M1

Trials

3 trial(s) available for cladribine and Acute Lymphoid Leukemia

ArticleYear
Pharmacokinetics of cladribine (2-chlorodeoxyadenosine) in children with acute leukemia.
    Cancer research, 1994, Mar-01, Volume: 54, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Bilirubin; Child; Child, Preschool; Cladribine; Creatinine; Drug Administration Schedule; Female; Half-Life; Humans; Infant; Infusions, Intravenous; Kidney; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests

1994
2-Chlorodeoxyadenosine produces a high rate of complete hematologic remission in relapsed acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:3

    Topics: 2-Chloroadenosine; Acute Disease; Adolescent; Adult; Antineoplastic Agents; Bone Marrow Transplantation; Child; Child, Preschool; Cladribine; Combined Modality Therapy; Deoxyadenosines; Drug Evaluation; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Regression Analysis; Remission Induction

1992
A phase I clinical trial of 2-chlorodeoxyadenosine in pediatric patients with acute leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:3

    Topics: 2-Chloroadenosine; Adolescent; Adult; Child; Child, Preschool; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Infant; Infusions, Intravenous; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1991

Other Studies

8 other study(ies) available for cladribine and Acute Lymphoid Leukemia

ArticleYear
The combination effects of bendamustine with antimetabolites against childhood acute lymphoblastic leukemia cells.
    International journal of hematology, 2016, Volume: 103, Issue:5

    Topics: Adenine Nucleotides; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Bendamustine Hydrochloride; Cell Line, Tumor; Cell Proliferation; Child; Cladribine; Clofarabine; Cytarabine; Drug Administration Schedule; Drug Synergism; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine

2016
In vitro sensitivity of leukemic cells to nucleoside derivatives in childhood acute leukemias: good activity in leukemic relapses.
    Neoplasma, 2005, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Cell Death; Child; Child, Preschool; Cladribine; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Tumor Cells, Cultured; Vidarabine

2005
Lipid raft disruption prevents apoptosis induced by 2-chloro-2'-deoxyadenosine (Cladribine) in leukemia cell lines.
    Leukemia research, 2006, Volume: 30, Issue:12

    Topics: Apoptosis; beta-Cyclodextrins; Calcium; Cell Line, Tumor; Chelating Agents; Cladribine; Drug Screening Assays, Antitumor; Egtazic Acid; Filipin; Humans; Membrane Microdomains; Nifedipine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors

2006
Use of stroma-supported cultures of leukemic cells to assess antileukemic drugs. II. Potent cytotoxicity of 2-chloro-deoxyadenosine in acute lymphoblastic leukemia.
    Leukemia, 1994, Volume: 8, Issue:7

    Topics: Adolescent; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Carrier Proteins; Cell Death; Child; Child, Preschool; Chromosome Aberrations; Cladribine; DNA Topoisomerases, Type II; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Infant; Infant, Newborn; Karyotyping; Membrane Glycoproteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Stromal Cells; Tumor Cells, Cultured

1994
In vitro activity of 2-chlorodeoxyadenosine (CdA) in primary cultures of human haematological and solid tumours.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:7

    Topics: Adrenocortical Carcinoma; Breast Neoplasms; Cladribine; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lung Neoplasms; Neoplasms; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

1994
Deoxycytidine in human plasma: potential for protecting leukemic cells during chemotherapy.
    Cancer letters, 1997, Jun-24, Volume: 116, Issue:2

    Topics: Adult; Cladribine; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine

1997
Enhancement of retention and cytotoxicity of 2-chlorodeoxyadenosine in cultured human leukemic lymphoblasts by nitrobenzylthioinosine, an inhibitor of equilibrative nucleoside transport.
    Leukemia, 2000, Volume: 14, Issue:1

    Topics: Antineoplastic Agents; Biological Transport; Chromatography, High Pressure Liquid; Cladribine; Drug Synergism; Humans; Nucleosides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioinosine; Tumor Cells, Cultured

2000
Cytotoxicity of 2-chlorodeoxyadenosine and arabinosylcytosine in leukaemic lymphoblasts from paediatric patients: significance of cellular nucleoside transporter content.
    British journal of haematology, 2002, Volume: 116, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carrier Proteins; Cell Survival; Child; Cladribine; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Immunophenotyping; Lymphocytes; Membrane Proteins; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

2002